Výsledky vyhledávání

Relationship between plasma rabbit anti‐thymocyte globulin concentration and immunosuppressive therapy response in patients with severe aplastic anemia

Autor: Asahito Hama, Nozomu Kawashima, Motoharu Hamada, Nobuhiro Nishio, Seiji Kojima, Eri Nishikawa, Shinji Nakao, Yusuke Okuno, Daisuke Ichikawa, Hideki Muramatsu, Kyogo Suzuki, Hirohito Yamazaki, Yoshiyuki Takahashi, Atsushi Narita

Publikováno v: European Journal of Haematology. 107:255-264

Objectives Patients with acquired aplastic anemia (AA) without HLA-matched sibling donors or aged >40 years receive immunosuppressive therapy (IST) with anti-thymocyte globulin (ATG). We investigated the relationship between plasma rabbit ATG (r-ATG)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc77462ccfff4d97e125eb13f94e48f
https://doi.org/10.1111/ejh.13644

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Long-term outcomes of 172 children with severe aplastic anemia treated with rabbit antithymocyte globulin and cyclosporine

Autor: Lixian Chang, Li-Peng Liu, Ye Guo, Meihui Yi, Yuanyuan Ren, Aoli Zhang, Chao Liu, Jing Feng, Shu-Chun Wang, Yang Lan, Yuli Cai, Xiaofan Zhu, Jingliao Zhang, Xiao-Yan Chen

Publikováno v: Annals of Hematology. 100:53-61

This study retrospectively analyzed the clinical outcome of 172 children with newly diagnosed severe aplastic anemia (SAA) between January 2008 and April 2018, who received rabbit antithymocyte globulin (ATG) and cyclosporine (CsA) as first-line trea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc76211cb34b41d2bdb6f5b49dbbe257
https://doi.org/10.1007/s00277-020-04296-9

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Efficacy and safety of porcine ALG compared to rabbit ATG as first‐line treatment for children with acquired aplastic anemia

Autor: G X Peng, Fengkui Zhang, L P Jing, Yuan Li, Song L, W R Yang, L Ye, Yangmin Zhu, Xin Zhao, Kang Zhou, H H Fan, Jianping Li, Yang Yang, Li Zhang, Yang Li

Publikováno v: European Journal of Haematology. 104:562-570

Objective To assess the outcomes of children with acquired aplastic anemia (AA) treated in China with first-line porcine anti-lymphocyte immunoglobulin (p-ALG)/rabbit anti-thymocyte immunoglobulin (r-ATG) combined with cyclosporine A (CSA). Methods W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67954b8ea6e429cff2b0299ce2927352
https://doi.org/10.1111/ejh.13398

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Impact of Two Different Types of Rabbit ATG on Immune Reconstitution and Overall Results after Allogeneic Hematopoetic Stem Cell Transplantation for Acute Lymphoblastic Leukemia in Children

Autor: Sylvie Chevret, Valérie Guérin, Mony Fahd, Jean-Hugues Dalle, Karima Yakouben, André Baruchel, Lou le Mouel, Camille Feltesse, Jérôme Le Goff, Marie Ouachee, Guislaine Carcelain

Publikováno v: Blood. 136:24-25

Introduction Thymoglobulin® and Grafalon® are 2 polyclonal rabbit anti-thymocyte globulin (ATG) used in allogeneic hematopoietic stem cell transplantation (allo-HSCT) to prevent graft rejection and graft-versus-host disease (GvHD). Differences in m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ca02515f21767c7490e94d9db3d4ad7
https://doi.org/10.1182/blood-2020-142374

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Prospective randomized trial comparing two doses of rabbit anti-thymocyte globulin in patients with severe aplastic anaemia

Autor: Hirohito Yamazaki, Shinji Nakao, Fang Liu, Seiji Kojima, Jong Wook Lee, Atsushi Narita, Wenyu Yang, Xiaojuan Chen, Hoon Kook, Kensuke Usuki, Jingliao Zhang, Yoshiyuki Takahashi, Jun H Jang, Xiaofan Zhu, Hawk Kim, Hideki Muramatsu, Ye Guo

Publikováno v: British journal of haematologyReferences. 187(2)

The treatment of choice for patients with severe aplastic anaemia (SAA) includes immunosuppressive therapy (IST) with anti-thymocyte globulin (ATG) and ciclosporin A. However, the optimal dose for rabbit ATG has yet to be established. We herein repor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b772e48327387bd951aa7962ef8147
https://pubmed.ncbi.nlm.nih.gov/31206607

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Akademický článek

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Diagnosis and management of childhood aplastic anaemia

Autor: Sujith Samarasinghe, Neha Bhatnagar

Publikováno v: Paediatrics and Child Health. 25:343-349

Aplastic anaemia is a rare disorder in children. ∼20% of cases are inherited, whilst the rest are considered as acquired or idiopathic where no cause can be found. Diagnosis of the inherited causes of aplastic anaemia can be challenging but it is i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::92f726747ef3b3d55610050abcaabe35
https://doi.org/10.1016/j.paed.2015.04.001

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Modified immunosuppressive therapy with porcine antilymphocyte globulin plus delayed cyclosporine A in children with severe aplastic anemia

Autor: Long-Mei Qin, Zhaoyue Wang, Hongshi Shen, Pingping Sha, Qing-Ya Cui, Tianqin Wu, Haifei Chen, Zhengyang Li

Publikováno v: International journal of hematology. 107(1)

Immunosuppressive therapy (IST) with antithymocyte globulin (ATG) and cyclosporine (CsA) is the standard treatment for children with severe aplastic anemia (SAA) with no human leukocyte antigen-matched siblings. Due to the unavailability of horse ATG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44da71bbf13c759e39e519306badcdd
https://pubmed.ncbi.nlm.nih.gov/28900860

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A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Rabbit ATG in the Prophylaxis of Acute Rejection in Lung Transplantation

Autor: Gregory I Snell, Charles W. Hoopes, Glen P. Westall, Bronwyn Levvey, Atul C. Mehta, Shaf Keshavjee, Peter Jaksch, Elbert P. Trulock, Vivek N. Ahya

Publikováno v: American Journal of Transplantation. 14:1191-1198

ATG-Fresenius S (ATG-F) is a polyclonal anti-human-T-lymphocyte immunoglobulin preparation that has been clinically developed to prevent episodes of acute cellular rejection. This study evaluated the efficacy and safety of ATG-F at doses of 5 and 9 m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc8b71244b9b65d90dc91bbcf691fffc
https://doi.org/10.1111/ajt.12663

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Rabbit Antithymocyte Globulin Treatment in Childhood Acquired Severe Aplastic Anemia

Autor: Kaan Kavakli, Nihal Karadaş, Deniz Yilmaz Karapinar, Can Balkan, Yilmaz Ay, Yesim Aydinok, Mehmet Akin

Publikováno v: Pediatric Hematology and Oncology. 31:20-28

Acquired severe aplastic anemia (SAA) is a life threatening bone marrow failure characterized by pancytopenia and hypocellular bone marrow. Matched sibling donor is not available for majority of the patients and many children receive immunosuppressiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c604e05acfdc9ec817e860a624361fe2
https://doi.org/10.3109/08880018.2013.792894

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