Identification of constrained sequence elements across 239 primate genomes.

Autor: Kuderna LFK; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Ulirsch JC; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Rashid S; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Ameen M; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Sundaram L; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Hickey G; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA., Cox AJ; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Gao H; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Kumar A; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Aguet F; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Christmas MJ; Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden., Clawson H; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA., Haeussler M; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA., Janiak MC; School of Science, Engineering and Environment, University of Salford, Salford, UK., Kuhlwilm M; Department of Evolutionary Anthropology, University of Vienna, Vienna, Austria.; Human Evolution and Archaeological Sciences (HEAS), University of Vienna, Vienna, Austria., Orkin JD; Département d'Anthropologie, Université de Montréal, Montréal, Quebec, Canada., Bataillon T; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark., Manu S; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; Laboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India., Valenzuela A; IBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain., Bergman J; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.; Section for Ecoinformatics and Biodiversity, Department of Biology, Aarhus University, Aarhus, Denmark., Rouselle M; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark., Silva FE; Research Group on Primate Biology and Conservation, Mamirauá Institute for Sustainable Development, Tefé, Brazil.; Evolutionary Biology and Ecology (EBE), Département de Biologie des Organismes, Université libre de Bruxelles (ULB), Brussels, Belgium., Agueda L; Centro Nacional de Analisis Genomico (CNAG), Barcelona, Spain., Blanc J; Centro Nacional de Analisis Genomico (CNAG), Barcelona, Spain., Gut M; Centro Nacional de Analisis Genomico (CNAG), Barcelona, Spain., de Vries D; School of Science, Engineering and Environment, University of Salford, Salford, UK., Goodhead I; School of Science, Engineering and Environment, University of Salford, Salford, UK., Harris RA; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Raveendran M; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Jensen A; Department of Ecology and Genetics, Animal Ecology, Uppsala University, Uppsala, Sweden., Chuma IS; Tanzania National Parks, Arusha, Tanzania., Horvath JE; North Carolina Museum of Natural Sciences, Raleigh, NC, USA.; Department of Biological and Biomedical Sciences, North Carolina Central University, Durham, NC, USA.; Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA.; Department of Evolutionary Anthropology, Duke University, Durham, NC, USA.; Renaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Hvilsom C; Copenhagen Zoo, Frederiksberg, Denmark., Juan D; IBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain., Frandsen P; Copenhagen Zoo, Frederiksberg, Denmark., Schraiber JG; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., de Melo FR; Universidade Federal de Viçosa, Viçosa, Brazil., Bertuol F; Universidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL), Manaus, Brazil., Byrne H; Department of Anthropology, University of Utah, Salt Lake City, UT, USA., Sampaio I; Universidade Federal do Para, Bragança, Brazil., Farias I; Universidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL), Manaus, Brazil., Valsecchi J; Research Group on Terrestrial Vertebrate Ecology, Mamirauá Institute for Sustainable Development, Tefé, Brazil.; Rede de Pesquisa em Diversidade, Conservação e Uso da Fauna da Amazônia - RedeFauna, Manaus, Brazil.; Comunidad de Manejo de Fauna Silvestre en la Amazonía y en Latinoamérica-ComFauna, Iquitos, Peru., Messias M; Universidade Federal de Rondônia, Porto Velho, Brazil., da Silva MNF; Instituto Nacional de Pesquisas da Amazônia, Manaus, Brazil., Trivedi M; Laboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India., Rossi R; Instituto de Biociências, Universidade Federal do Mato Grosso, Cuiabá, Brazil., Hrbek T; Universidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL), Manaus, Brazil.; Department of Biology, Trinity University, San Antonio, TX, USA., Andriaholinirina N; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga, Mahajanga, Madagascar., Rabarivola CJ; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga, Mahajanga, Madagascar., Zaramody A; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga, Mahajanga, Madagascar., Jolly CJ; Department of Anthropology, New York University, New York, NY, USA., Phillips-Conroy J; Department of Neuroscience, Washington University School of Medicine in St Louis, St Louis, MO, USA., Wilkerson G; Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center, Bastrop, TX, USA., Abee C; Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center, Bastrop, TX, USA., Simmons JH; Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center, Bastrop, TX, USA., Fernandez-Duque E; Department of Anthropology, Yale University, New Haven, CT, USA., Kanthaswamy S; School of Interdisciplinary Forensics, Arizona State University, Phoenix, AZ, USA.; California National Primate Research Center, University of California, Davis, CA, USA., Shiferaw F; Guinea Worm Eradication Program, The Carter Center Ethiopia, Addis Ababa, Ethiopia., Wu D; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China., Zhou L; Center for Evolutionary and Organismal Biology, Zhejiang University School of Medicine, Hangzhou, China., Shao Y; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China., Zhang G; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.; Center for Evolutionary and Organismal Biology, Zhejiang University School of Medicine, Hangzhou, China.; Villum Centre for Biodiversity Genomics, Section for Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen, Denmark.; Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, China.; Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Keyyu JD; Tanzania Wildlife Research Institute (TAWIRI), Arusha, Tanzania., Knauf S; Institute of International Animal Health/One Health, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.; Professorship for International Animal Health/One Health, Faculty of Veterinary Medicine, Justus Liebig University, Giessen, Germany., Le MD; Department of Environmental Ecology, Faculty of Environmental Sciences, University of Science and Central Institute for Natural Resources and Environmental Studies, Vietnam National University, Hanoi, Vietnam., Lizano E; IBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.; Institut Català de Paleontologia Miquel Crusafont, Universitat Autònoma de Barcelona, Barcelona, Spain., Merker S; Department of Zoology, State Museum of Natural History Stuttgart, Stuttgart, Germany., Navarro A; IBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain., Nadler T; Cuc Phuong Commune, Nho Quan District, Vietnam., Khor CC; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore., Lee J; Mandai Nature, Singapore, Singapore., Tan P; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.; SingHealth Duke-NUS Institute of Precision Medicine (PRISM), Singapore, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore., Lim WK; SingHealth Duke-NUS Institute of Precision Medicine (PRISM), Singapore, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore.; SingHealth Duke-NUS Genomic Medicine Centre, Singapore, Singapore., Kitchener AC; Department of Natural Sciences, National Museums Scotland, Edinburgh, UK.; School of Geosciences, Edinburgh, UK., Zinner D; Cognitive Ethology Laboratory, Germany Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany.; Department of Primate Cognition, Georg-August-Universität Göttingen, Göttingen, Germany.; Leibniz ScienceCampus Primate Cognition, Göttingen, Germany., Gut I; Centro Nacional de Analisis Genomico (CNAG), Barcelona, Spain., Melin AD; Department of Anthropology and Archaeology, University of Calgary, Calgary, Alberta, Canada.; Department of Medical Genetics, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada., Guschanski K; Department of Ecology and Genetics, Animal Ecology, Uppsala University, Uppsala, Sweden.; Institute of Ecology and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh, UK., Schierup MH; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark., Beck RMD; School of Science, Engineering and Environment, University of Salford, Salford, UK., Karakikes I; Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Department of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA., Wang KC; Department of Cancer Biology, Stanford University, Stanford, CA, USA.; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, USA.; Veterans Affairs Palo Alto Healthcare System, Palo Alto, CA, USA., Umapathy G; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; Laboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India., Roos C; Gene Bank of Primates and Primate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany., Boubli JP; School of Science, Engineering and Environment, University of Salford, Salford, UK., Siepel A; Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Kundaje A; Department of Computer Science, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA., Paten B; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA., Lindblad-Toh K; Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Rogers J; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA. jr13@bcm.edu., Marques Bonet T; IBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain. tomas.marques@upf.edu.; Centro Nacional de Analisis Genomico (CNAG), Barcelona, Spain. tomas.marques@upf.edu.; Institut Català de Paleontologia Miquel Crusafont, Universitat Autònoma de Barcelona, Barcelona, Spain. tomas.marques@upf.edu.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain. tomas.marques@upf.edu.; Universitat Pompeu Fabra, Barcelona, Spain. tomas.marques@upf.edu., Farh KK; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA. kfarh@illumina.com.

Publikováno v: Nature [Nature] 2024 Jan; Vol. 625 (7996), pp. 735-742. Date of Electronic Publication: 2023 Nov 29.

The landscape of tolerated genetic variation in humans and primates.

Autor: Gao H; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA., Hamp T; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA., Ede J; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA., Schraiber JG; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA., McRae J; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA., Singer-Berk M; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Boston, MA, 02142, USA., Yang Y; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA., Dietrich ASD; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA., Fiziev PP; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA., Kuderna LFK; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA.; Institute of Evolutionary Biology (UPF-CSIC), PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain., Sundaram L; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA., Wu Y; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA., Adhikari A; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA., Field Y; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA., Chen C; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA., Batzoglou S; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA., Aguet F; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA., Lemire G; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Boston, MA, 02142, USA.; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Reimers R; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA., Balick D; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA.; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Janiak MC; School of Science, Engineering & Environment, University of Salford, Salford M5 4WT, UK., Kuhlwilm M; Institute of Evolutionary Biology (UPF-CSIC), PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.; Department of Evolutionary Anthropology, University of Vienna, Djerassiplatz 1, 1030 Vienna, Austria.; Human Evolution and Archaeological Sciences (HEAS), University of Vienna, 1030 Vienna, Austria., Orkin JD; Institute of Evolutionary Biology (UPF-CSIC), PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.; Département d'anthropologie, Université de Montréal, 3150 Jean-Brillant, Montréal, QC H3T 1N8, Canada., Manu S; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.; Laboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology, Hyderabad 500007, India., Valenzuela A; Institute of Evolutionary Biology (UPF-CSIC), PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain., Bergman J; Bioinformatics Research Centre, Aarhus University, Aarhus 8000, Denmark.; Section for Ecoinformatics & Biodiversity, Department of Biology, Aarhus University, 8000 Aarhus, Denmark., Rousselle M; Bioinformatics Research Centre, Aarhus University, Aarhus 8000, Denmark., Silva FE; Research Group on Primate Biology and Conservation, Mamirauá Institute for Sustainable Development, Estrada da Bexiga 2584, Tefé, Amazonas, CEP 69553-225, Brazil.; Evolutionary Biology and Ecology (EBE), Département de Biologie des Organismes, Université libre de Bruxelles (ULB), Av. Franklin D. Roosevelt 50, CP 160/12, B-1050 Brussels, Belgium., Agueda L; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Baldiri i Reixac 4, 08028 Barcelona, Spain., Blanc J; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Baldiri i Reixac 4, 08028 Barcelona, Spain., Gut M; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Baldiri i Reixac 4, 08028 Barcelona, Spain., de Vries D; School of Science, Engineering & Environment, University of Salford, Salford M5 4WT, UK., Goodhead I; School of Science, Engineering & Environment, University of Salford, Salford M5 4WT, UK., Harris RA; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Raveendran M; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Jensen A; Department of Ecology and Genetics, Animal Ecology, Uppsala University, SE-75236 Uppsala, Sweden., Chuma IS; Tanzania National Parks, Arusha, Tanzania., Horvath JE; North Carolina Museum of Natural Sciences, Raleigh, NC 27601, USA.; Department of Biological and Biomedical Sciences, North Carolina Central University, Durham, NC 27707, USA.; Department of Biological Sciences, North Carolina State University, Raleigh, NC 27695, USA.; Department of Evolutionary Anthropology, Duke University, Durham, NC 27708, USA.; Renaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Hvilsom C; Copenhagen Zoo, 2000 Frederiksberg, Denmark., Juan D; Institute of Evolutionary Biology (UPF-CSIC), PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain., Frandsen P; Copenhagen Zoo, 2000 Frederiksberg, Denmark., de Melo FR; Universidade Federal de Viçosa, Viçosa, 36570-900, Brazil., Bertuol F; Universidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL), Manaus, Amazonas, 69080-900, Brazil., Byrne H; Department of Anthropology, University of Utah, Salt Lake City, UT 84102, USA., Sampaio I; Universidade Federal do Para, Guamá, Belém - PA, 66075-110, Brazil., Farias I; Universidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL), Manaus, Amazonas, 69080-900, Brazil., do Amaral JV; Research Group on Terrestrial Vertebrate Ecology, Mamirauá Institute for Sustainable Development, Tefé, Amazonas, 69553-225, Brazil.; Rede de Pesquisa para Estudos sobre Diversidade, Conservação e Uso da Fauna na Amazônia - RedeFauna, Manaus, Amazonas, 69080-900, Brazil.; Comunidad de Manejo de Fauna Silvestre en la Amazonía y en Latinoamérica - ComFauna, Iquitos, Loreto, 16001, Peru., Messias M; Universidade Federal de Rondonia, Porto Velho, Rondônia, 78900-000, Brazil.; PPGREN - Programa de Pós-Graduação 'Conservação e Uso dos Recursos Naturais and BIONORTE - Programa de Pós-Graduação em Biodiversidade e Biotecnologia da Rede BIONORTE, Universidade Federal de Rondonia, Porto Velho, Rondônia, 78900-000, Brazil., da Silva MNF; Instituto Nacional de Pesquisas da Amazonia, Petrópolis, Manaus - AM, 69067-375, Brazil., Trivedi M; Laboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology, Hyderabad 500007, India., Rossi R; Universidade Federal do Mato Grosso, Boa Esperança, Cuiabá - MT, 78060-900, Brazil., Hrbek T; Universidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL), Manaus, Amazonas, 69080-900, Brazil.; Department of Biology, Trinity University, San Antonio, TX 78212, USA., Andriaholinirina N; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga, Mahajanga, 401, Madagascar., Rabarivola CJ; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga, Mahajanga, 401, Madagascar., Zaramody A; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga, Mahajanga, 401, Madagascar., Jolly CJ; New York University, New York City, NY 10012, USA., Phillips-Conroy J; Washington University in St. Louis, St. Louis, MO 63130, USA., Wilkerson G; Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center, Houston, TX 77030, USA., Abee C; Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center, Houston, TX 77030, USA., Simmons JH; Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center, Houston, TX 77030, USA., Fernandez-Duque E; Yale University, New Haven, CT 06520, USA.; Universidad Nacional de Formosa, Argentina Fundacion ECO, Formosa, Argentina., Kanthaswamy S; Arizona State University, Tempe, AZ 85281, USA., Shiferaw F; Guinea Worm Eradication Program, The Carter Center Ethiopia, PoB 16316, Addis Ababa 1000, Ethiopia., Wu D; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China., Zhou L; Center for Evolutionary & Organismal Biology, Zhejiang University School of Medicine, Hangzhou 310058, China., Shao Y; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China., Zhang G; Center for Evolutionary & Organismal Biology, Zhejiang University School of Medicine, Hangzhou 310058, China.; Villum Center for Biodiversity Genomics, Section for Ecology and Evolution, Department of Biology, University of Copenhagen, DK-2100 Copenhagen, Denmark.; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, Hangzhou 311121, China.; Women's Hospital, School of Medicine, Zhejiang University, 1 Xueshi Road, Shangcheng District, Hangzhou 310006, China., Keyyu JD; Tanzania Wildlife Research Institute (TAWIRI), Head Office, P.O. Box 661, Arusha, Tanzania., Knauf S; Institute of International Animal Health/One Health, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald - Insei Riems, Germany., Le MD; Department of Environmental Ecology, Faculty of Environmental Sciences, University of Science and Central Institute for Natural Resources and Environmental Studies, Vietnam National University, Hanoi 100000, Vietnam., Lizano E; Institute of Evolutionary Biology (UPF-CSIC), PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.; Catalan Institution of Research and Advanced Studies (ICREA), Passeig de Lluís Companys, 23, 08010 Barcelona, Spain., Merker S; Department of Zoology, State Museum of Natural History Stuttgart, 70191 Stuttgart, Germany., Navarro A; Institute of Evolutionary Biology (UPF-CSIC), PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.; Institut Català de Paleontologia Miquel Crusafont, Universitat Autònoma de Barcelona, Edifici ICTA-ICP, c/ Columnes s/n, 08193 Cerdanyola del Vallès, Barcelona, Spain.; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Av. Doctor Aiguader, N88, 08003 Barcelona, Spain.; BarcelonaBeta Brain Research Center, Pasqual Maragall Foundation, C. Wellington 30, 08005 Barcelona, Spain., Bataillon T; Bioinformatics Research Centre, Aarhus University, Aarhus 8000, Denmark., Nadler T; Cuc Phuong Commune, Nho Quan District, Ninh Binh Province 430000, Vietnam., Khor CC; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), 60 Biopolis Street, Genome, Singapore 138672, Republic of Singapore., Lee J; Mandai Nature, 80 Mandai Lake Road, Singapore 729826, Republic of Singapore., Tan P; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), 60 Biopolis Street, Genome, Singapore 138672, Republic of Singapore.; SingHealth Duke-NUS Institute of Precision Medicine (PRISM), Singapore 168582, Republic of Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore 168582, Republic of Singapore., Lim WK; SingHealth Duke-NUS Institute of Precision Medicine (PRISM), Singapore 168582, Republic of Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore 168582, Republic of Singapore.; SingHealth Duke-NUS Genomic Medicine Centre, Singapore 168582, Republic of Singapore., Kitchener AC; Department of Natural Sciences, National Museums Scotland, Chambers Street, Edinburgh EH1 1JF, UK.; School of Geosciences, University of Edinburgh, Drummond Street, Edinburgh EH8 9XP, UK., Zinner D; Cognitive Ethology Laboratory, Germany Primate Center, Leibniz Institute for Primate Research, 37077 Göttingen, Germany.; Department of Primate Cognition, Georg-August-Universität Göttingen, 37077 Göttingen, Germany.; Leibniz Science Campus Primate Cognition, 37077 Göttingen, Germany., Gut I; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Baldiri i Reixac 4, 08028 Barcelona, Spain.; Universitat Pompeu Fabra, Pg. Luís Companys 23, 08010 Barcelona, Spain., Melin A; Department of Anthropology & Archaeology, University of Calgary, 2500 University Dr NW, Calgary, AB T2N 1N4, Canada.; Department of Medical Genetics, 3330 Hospital Drive NW, HMRB 202, Calgary, AB T2N 4N1, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, 2500 University Dr NW, Calgary, AB T2N 1N4, Canada., Guschanski K; Department of Ecology and Genetics, Animal Ecology, Uppsala University, SE-75236 Uppsala, Sweden.; Institute of Ecology and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh EH8 9XP, UK., Schierup MH; Bioinformatics Research Centre, Aarhus University, Aarhus 8000, Denmark., Beck RMD; School of Science, Engineering & Environment, University of Salford, Salford M5 4WT, UK., Umapathy G; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.; Laboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology, Hyderabad 500007, India., Roos C; Gene Bank of Primates and Primate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research, Kellnerweg 4, 37077 Göttingen, Germany., Boubli JP; School of Science, Engineering & Environment, University of Salford, Salford M5 4WT, UK., Lek M; Department of Genetics, Yale School of Medicine, New Haven, CT 06520, USA., Sunyaev S; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA.; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA., O'Donnell-Luria A; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Boston, MA, 02142, USA.; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02115, USA., Rehm HL; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Boston, MA, 02142, USA.; Department of Genetics, Yale School of Medicine, New Haven, CT 06520, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA., Xu J; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA.; Toyota Technological Institute at Chicago, Chicago, IL 60637, USA., Rogers J; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Marques-Bonet T; Institute of Evolutionary Biology (UPF-CSIC), PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Baldiri i Reixac 4, 08028 Barcelona, Spain.; Catalan Institution of Research and Advanced Studies (ICREA), Passeig de Lluís Companys, 23, 08010 Barcelona, Spain.; Institut Català de Paleontologia Miquel Crusafont, Universitat Autònoma de Barcelona, Edifici ICTA-ICP, c/ Columnes s/n, 08193 Cerdanyola del Vallès, Barcelona, Spain., Farh KK; Illumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA, 94404, USA.

Publikováno v: Science (New York, N.Y.) [Science] 2023 Jun 02; Vol. 380 (6648), pp. eabn8153. Date of Electronic Publication: 2023 Jun 02.

Variation in predicted COVID-19 risk among lemurs and lorises.

Autor: Melin AD; Department of Anthropology and Archaeology, University of Calgary, Alberta, Canada.; Department of Medical Genetics, University of Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Alberta, Canada., Orkin JD; Experimental and Health Sciences Department (DCEXS), Institut de Biologia Evolutiva, Universitat Pompeu Fabra-CSIC, Barcelona, Spain., Janiak MC; School of Science, Engineering & Environment, University of Salford, Salford, UK., Valenzuela A; Experimental and Health Sciences Department (DCEXS), Institut de Biologia Evolutiva, Universitat Pompeu Fabra-CSIC, Barcelona, Spain., Kuderna L; Experimental and Health Sciences Department (DCEXS), Institut de Biologia Evolutiva, Universitat Pompeu Fabra-CSIC, Barcelona, Spain., Marrone F 3rd; Department of Chemistry, New York University, New York, USA., Ramangason H; Department of Anthropology and Archaeology, University of Calgary, Alberta, Canada., Horvath JE; Genomics & Microbiology Research Laboratory, North Carolina Museum of Natural Sciences, Raleigh, North Carolina, USA.; Department of Biological and Biomedical Sciences, North Carolina Central University, Durham, North Carolina, USA.; Department of Evolutionary Anthropology, Duke University, Durham, North Carolina, USA.; Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA., Roos C; Gene Bank of Primates and Primate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research, Göettingen, Germany., Kitchener AC; Department of Natural Sciences, National Museums Scotland and School of Geosciences, University of Edinburgh, Edinburgh, UK., Khor CC; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore., Lim WK; SingHealth Duke-NUS Institute of Precision Medicine, Singapore Health Services, Singapore.; SingHealth Duke-NUS Genomic Medicine Centre, Singapore Health Services, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Lee JGH; Department of Conservation, Research and Veterinary Services, Wildlife Reserves Singapore, Singapore., Tan P; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore.; SingHealth Duke-NUS Institute of Precision Medicine, Singapore Health Services, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Umapathy G; CSIR-Laboratory for the Conservation of Endangered Species, Centre for Cellular and Molecular Biology, Hyderabad, India., Raveendran M; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA., Alan Harris R; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA., Gut I; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Gut M; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Lizano E; Experimental and Health Sciences Department (DCEXS), Institut de Biologia Evolutiva, Universitat Pompeu Fabra-CSIC, Barcelona, Spain., Nadler T; Cuc Phuong Commune, Nho Quan District, Ninh Binh Province, Vietnam., Zinner D; Cognitive Ethology Laboratory, German Primate Center, Leibniz Institute for Primate Research, Goettingen, Germany.; Leibniz Science Campus Primate Cognition, Goettingen, Germany.; Department of Primate Cognition, Georg-August-University, Goettingen, Germany., Le MD; Department of Environmental Ecology, University of Science and Central Institute for Natural Resources and Environmental Studies, Vietnam National University, Hanoi, Vietnam., Manu S; CSIR-Laboratory for the Conservation of Endangered Species, Centre for Cellular and Molecular Biology, Hyderabad, India., Rabarivola CJ; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga, Mahajanga, Madagascar., Zaramody A; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga, Mahajanga, Madagascar., Andriaholinirina N; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga, Mahajanga, Madagascar., Johnson SE; Department of Anthropology and Archaeology, University of Calgary, Alberta, Canada., Jarvis ED; The Vertebrate Genomes Lab, The Rockefeller University, New York, New York, USA.; Laboratory of Neurogenetics of Language, The Rockefeller University, New York, United States.; Howard Hughes Medical Institute, Chevy Chase, Maryland, USA., Fedrigo O; The Vertebrate Genomes Lab, The Rockefeller University, New York, New York, USA.; Howard Hughes Medical Institute, Chevy Chase, Maryland, USA., Wu D; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.; Kunming Natural History Museum of Zoology, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China., Zhang G; Villum Center for Biodiversity Genomics, Section for Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen, Denmark.; China National Genebank, BGI-Shenzhen, Shenzhen, China.; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, China., Farh KK; Artificial Intelligence Lab, Illumina Inc, San Diego, California, USA., Rogers J; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA., Marques-Bonet T; Experimental and Health Sciences Department (DCEXS), Institut de Biologia Evolutiva, Universitat Pompeu Fabra-CSIC, Barcelona, Spain.; Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain.; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Institut Català de Paleontologia Miquel Crusafont, Universitat Autònoma de Barcelona, Barcelona, Spain., Navarro A; Experimental and Health Sciences Department (DCEXS), Institut de Biologia Evolutiva, Universitat Pompeu Fabra-CSIC, Barcelona, Spain.; Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain.; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Juan D; Experimental and Health Sciences Department (DCEXS), Institut de Biologia Evolutiva, Universitat Pompeu Fabra-CSIC, Barcelona, Spain., Arora PS; Department of Chemistry, New York University, New York, USA., Higham JP; Department of Anthropology, New York University, New York, New York, USA.; New York Consortium in Evolutionary Primatology, New York, New York, USA.

Publikováno v: American journal of primatology [Am J Primatol] 2021 Jun; Vol. 83 (6), pp. e23255. Date of Electronic Publication: 2021 Apr 01.