Zobrazeno 1 - 10
of 232
pro vyhledávání: '"Raajit K. Rampal"'
Autor:
Pankit Vachhani, John Mascarenhas, Prithviraj Bose, Gabriela Hobbs, Abdulraheem Yacoub, Jeanne M. Palmer, Aaron T. Gerds, Lucia Masarova, Andrew T. Kuykendall, Raajit K. Rampal, Ruben Mesa, Srdan Verstovsek
Publikováno v:
Therapeutic Advances in Hematology, Vol 15 (2024)
Interferons are cytokines with immunomodulatory properties and disease-modifying effects that have been used to treat myeloproliferative neoplasms (MPNs) for more than 35 years. The initial use of interferons was limited due to difficulties with admi
Externí odkaz:
https://doaj.org/article/f914014456cf435ebd924c6e619ff22a
Publikováno v:
Therapeutic Advances in Hematology, Vol 14 (2023)
Myeloproliferative neoplasms (MPNs) are a group of clonal hematologic malignancies that include polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF). MPNs are characterized by activating mutations in the JAK/STAT pathway and
Externí odkaz:
https://doaj.org/article/ec6fb4abea7743a6a9319ac4596a0ddf
Autor:
Xiaoli Wang, Raajit K. Rampal, Cing Siang Hu, Joseph Tripodi, Noushin Farnoud, Bruce Petersen, Michael R. Rossi, Minal Patel, Erin McGovern, Vesna Najfeld, Camelia Iancu-Rubin, Min Lu, Andrew Davis, Marina Kremyanskaya, Rona Singer Weinberg, John Mascarenhas, Ronald Hoffman
Publikováno v:
JCI Insight, Vol 7, Iss 8 (2022)
Chronic myeloproliferative neoplasms (MPN) frequently evolve to a blast phase (BP) that is almost uniformly resistant to induction chemotherapy or hypomethylating agents. We explored the functional properties, genomic architecture, and cell of origin
Externí odkaz:
https://doaj.org/article/7d3e09d68f224b1fb0cde749aceeada5
Autor:
Dan Liu, Zefeng Xu, Peihong Zhang, Tiejun Qin, Xiujuan Sun, Shiqiang Qu, Lijuan Pan, Jiao Ma, Wenyu Cai, Jinqin Liu, Huijun Wang, Qi Sun, Zhongxun Shi, Huijun Huang, Gang Huang, Robert Peter Gale, Bing Li, Raajit K. Rampal, Zhijian Xiao
Publikováno v:
Haematologica, Vol 107, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/bd6b9167748c48d5b416fb97f8f0e086
Autor:
Anastasia Navitski, Duaa H. Al-Rawi, Ying Liu, Maria M. Rubinstein, Claire F. Friedman, Raajit K. Rampal, Diana L. Mandelker, Karen Cadoo, Roisin E. O'Cearbhaill
Publikováno v:
Gynecologic Oncology Reports, Vol 38, Iss , Pp 100873- (2021)
Poly(ADP-ribose) polymerase inhibitors (PARPi) are FDA approved as frontline maintenance for BRCA-associated advanced stage high-grade ovarian cancer (HGOC), having demonstrated an unprecedented improvement in relapse-free survival. Myelodysplastic s
Externí odkaz:
https://doaj.org/article/5dec3a4009954488a69ec3bc6e83b29d
Autor:
Amber C. King, Eli L. Diamond, Jennifer S. Orozco, Hannah R. Morse, Linda L. Ouyang, Heiko Schöder, Raajit K. Rampal
Publikováno v:
Clinical Case Reports, Vol 7, Iss 10, Pp 1989-1993 (2019)
Abstract Our rechallenge of cobimetinib in an Erdheim‐Chester Disease (ECD) patient for the rare adverse effect, “dropped head syndrome,” with a previously unexplored cobimetinib regimen was successful. Similar to other experiences with targete
Externí odkaz:
https://doaj.org/article/9e1e6f10b4fd4244b1452a2eef66da91
Publikováno v:
Biomarker Research, Vol 7, Iss 1, Pp 1-8 (2019)
Abstract The discovery of JAK2V617F and the demonstration that BCR-ABL-negative myeloproliferative neoplasms (MPNs) are driven by abnormal JAK2 activation have led to advances in diagnostic algorithms, prognosis and ultimately also treatment strategi
Externí odkaz:
https://doaj.org/article/e6b4d6190d854b8d8cac22be14914690
Autor:
Brian J. Chernak, Filiz Sen, Noushin Farnoud, Jad Bou Ayache, Yanming Zhang, Susan DeWolf, Raajit K. Rampal
Publikováno v:
HemaSphere, Vol 4, Iss 4, p e411 (2020)
Externí odkaz:
https://doaj.org/article/4f291b955f004f3ba2e3bc40e7974a23
Autor:
Gabriela S. Hobbs, Amritha Varshini Hanasoge Somasundara, Maria Kleppe, Rivka Litvin, Maria Arcila, Jihae Ahn, Anna Sophia McKenney, Kristina Knapp, Ryan Ptashkin, Howard Weinstein, Murk-Hein Heinemann, Jasmine Francis, Suzanne Chanel, Ellin Berman, Michael Mauro, Martin S. Tallman, Mark L. Heaney, Ross L. Levine, Raajit K. Rampal
Publikováno v:
Haematologica, Vol 103, Iss 1 (2018)
Externí odkaz:
https://doaj.org/article/562c84fe1892430fb07bda7a916c5530
Autor:
Catherine C. Coombs, David A. Sallman, Sean M. Devlin, Shweta Dixit, Abhinita Mohanty, Kristina Knapp, Najla H. Al Ali, Jeffrey E. Lancet, Alan F. List, Rami S. Komrokji, Eric Padron, Maria E. Arcila, Virginia M. Klimek, Marcel R. M. van den Brink, Martin S. Tallman, Ross L. Levine, Raajit K. Rampal, Franck Rapaport
Publikováno v:
Haematologica, Vol 101, Iss 11 (2016)
Externí odkaz:
https://doaj.org/article/164d8500288c4318ae19e0d3e8421161