Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Raad Z Gharaibeh"'
Autor:
Huijia Liu, John W. Birk, Anthony A. Provatas, Haleh Vaziri, Nuoxi Fan, Daniel W. Rosenberg, Raad Z. Gharaibeh, Christian Jobin
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract This study is to investigate the relationship between the intestinal microbiota and urine levels of the ellagic acid-derived polyphenols, the urolithins, in a cohort of subjects following a three-week walnut dietary intervention. We longitud
Externí odkaz:
https://doaj.org/article/6731f0e1a2b9428e82fd4de191285377
Autor:
Ross M Maltz, Jeremy Keirsey, Sandra C Kim, Amy R Mackos, Raad Z Gharaibeh, Cathy C Moore, Jinyu Xu, Vasudevan Bakthavatchalu, Arpad Somogyi, Michael T Bailey
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196961 (2018)
Stressor-exposure has been shown to exacerbate inflammation and change the composition of the gastrointestinal microbiota; however stressor-induced effects on microbiota-derived metabolites and their receptors are unknown. Thus, bacterial-produced sh
Externí odkaz:
https://doaj.org/article/4abe4e71f73e4d37a71b6601f5c24137
Autor:
Pyoung Hwa Park, Kelsey Keith, Gennaro Calendo, Jaroslav Jelinek, Jozef Madzo, Raad Z. Gharaibeh, Jayashri Ghosh, Carmen Sapienza, Christian Jobin, Jean-Pierre J. Issa
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
The intestinal microbiota is an important environmental factor implicated in CRC development. Intriguingly, modulation of DNA methylation by gut microbiota has been reported in preclinical models, although the relationship between tumor-infiltrating
Externí odkaz:
https://doaj.org/article/2856375f622b4bc5bda4e07109ea89fe
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14464 (2010)
Microarray technology is a commonly used tool for assessing global gene expression. Many models for estimation of target concentration based on observed microarray signal have been proposed, but, in general, these models have been complex and platfor
Externí odkaz:
https://doaj.org/article/cabc04960f7b457db35b8a62016184f2
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11048 (2010)
The probe percent bound value, calculated using multi-state equilibrium models of solution hybridization, is shown to be useful in understanding the hybridization behavior of microarray probes having 50 nucleotides, with and without mismatches. These
Externí odkaz:
https://doaj.org/article/7a2e79113b824478931beaad86680ccb
Autor:
Megan M. Knuth, Jing Xue, Marwa Elnagheeb, Raad Z. Gharaibeh, Sarah A. Schoenrock, Susan McRitchie, Cory Brouwer, Susan J. Sumner, Lisa Tarantino, William Valdar, R. Scott Rector, Jeremy M. Simon, Folami Ideraabdullah
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionEmerging data suggests liver disease may be initiated during development when there is high genome plasticity and the molecular pathways supporting liver function are being developed.MethodsHere, we leveraged our Collaborative Cross mouse
Externí odkaz:
https://doaj.org/article/8293d185b25b4bafb987226841c7403f
Autor:
Michael W. Dougherty, Rafael Valdés-Mas, Kevin M. Wernke, Raad Z. Gharaibeh, Ye Yang, Jason O. Brant, Alberto Riva, Marcus Muehlbauer, Eran Elinav, Jens Puschhof, Seth B. Herzon, Christian Jobin
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 43, Iss , Pp 100918- (2023)
Certain Enterobacteriaceae strains contain a 54-kb biosynthetic gene cluster referred to as “pks” encoding the biosynthesis of a secondary metabolite, colibactin. Colibactin-producing E. coli promote colorectal cancer (CRC) in preclinical models,
Externí odkaz:
https://doaj.org/article/be1c3e9769744513b42cb4dbc20b7f19
Autor:
Qin Yu, Rachel C. Newsome, Mark Beveridge, Maria C. Hernandez, Raad Z. Gharaibeh, Christian Jobin, Ryan M. Thomas
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Preclinical data demonstrate that the gut microbiota can promote pancreatic ductal adenocarcinoma (PDAC), but mechanisms remain unclear. We hypothesized that intestinal microbiota alters anti-tumor innate immunity response to facilitate PDAC progress
Externí odkaz:
https://doaj.org/article/2858803b71ee4d7daa38553db53e6d16
Autor:
Melissa Ellermann, Raad Z. Gharaibeh, Nitsan Maharshak, Ernesto Peréz-Chanona, Christian Jobin, Ian M. Carroll, Janelle C. Arthur, Scott E Plevy, Anthony A. Fodor, Cory R. Brouwer, R. Balfour Sartor
Publikováno v:
Gut Microbes, Vol 11, Iss 1, Pp 32-50 (2020)
Iron deficiency, a common comorbidity of gastrointestinal inflammatory disorders such as inflammatory bowel diseases (IBD), is often treated with oral iron supplementation. However, the safety of oral iron supplementation remains controversial becaus
Externí odkaz:
https://doaj.org/article/1fdb8904e67b42ca83844eca09989e6a
Autor:
Rachel C. Newsome, Josee Gauthier, Maria C. Hernandez, George E. Abraham, Tanya O. Robinson, Haley B. Williams, Meredith Sloan, Anna Owings, Hannah Laird, Taylor Christian, Yilianys Pride, Kenneth J. Wilson, Mohammad Hasan, Adam Parker, Michal Senitko, Sarah C. Glover, Raad Z. Gharaibeh, Christian Jobin
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
To investigate the relationship between intestinal microbiota and SARS-CoV-2-mediated pathogenicity in a United States, majority African American cohort. We prospectively collected fecal samples from 50 SARS-CoV-2 infected patients, 9 SARS-CoV-2 reco
Externí odkaz:
https://doaj.org/article/96685b2fdf614995a7d3332aa38157fb