Výsledky vyhledávání - "Raül Rigo-Bonnin"

Akademický článek

Comparative Efficacy of Continuous Ceftazidime Infusion vs. Intermittent Bolus against In Vitro Ceftazidime-Susceptible and -Resistant Pseudomonas aeruginosa Biofilm

Autor: Cristina El Haj, Eugènia Agustí, Eva Benavent, Laura Soldevila-Boixader, Raül Rigo-Bonnin, Fe Tubau, Benjamín Torrejón, Jaime Esteban, Oscar Murillo

Publikováno v: Antibiotics, Vol 13, Iss 4, p 344 (2024)

Background: As the anti-biofilm pharmacokinetic/pharmacodynamic (PK/PD) properties of antibiotics are not well-defined, we have evaluated the PK/PD indices for different regimens of ceftazidime (CAZ; with/without colistin) against Pseudomonas aerugin

Externí odkaz: https://doaj.org/article/a5718c5305c743fd93ffad1b8f37c169

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Akademický článek

The Effect of Intracellular Tacrolimus Exposure on Calcineurin Inhibition in Immediate- and Extended-Release Tacrolimus Formulations

Autor: Pere Fontova, Lisanne N. van Merendonk, Anna Vidal-Alabró, Raül Rigo-Bonnin, Gema Cerezo, Stefaan van Oevelen, Oriol Bestard, Edoardo Melilli, Nuria Montero, Ana Coloma, Anna Manonelles, Joan Torras, Josep M. Cruzado, Josep M. Grinyó, Helena Colom, Nuria Lloberas

Publikováno v: Pharmaceutics, Vol 15, Iss 5, p 1481 (2023)

Despite intensive monitoring of whole blood tacrolimus concentrations, acute rejection after kidney transplantation occurs during tacrolimus therapy. Intracellular tacrolimus concentrations could better reflect exposure at the site of action and its

Externí odkaz: https://doaj.org/article/17151f14f7b844a0abfe1718be0a1db2

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Akademický článek

Predictive Factors of Piperacillin Exposure and the Impact on Target Attainment after Continuous Infusion Administration to Critically Ill Patients

Autor: Javier Martínez-Casanova, Erika Esteve-Pitarch, Helena Colom-Codina, Víctor Daniel Gumucio-Sanguino, Sara Cobo-Sacristán, Evelyn Shaw, Kristel Maisterra-Santos, Joan Sabater-Riera, Xosé L. Pérez-Fernandez, Raül Rigo-Bonnin, Fe Tubau-Quintano, Jordi Carratalà, Ariadna Padullés-Zamora

Publikováno v: Antibiotics, Vol 12, Iss 3, p 531 (2023)

Critically ill patients undergo significant pathophysiological changes that affect antibiotic pharmacokinetics. Piperacillin/tazobactam administered by continuous infusion (CI) improves pharmacokinetic/pharmacodynamic (PK/PD) target attainment. This

Externí odkaz: https://doaj.org/article/7d332f6e743a44688ac604b8a5c70ea0

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Akademický článek

Influence of the Circadian Timing System on Tacrolimus Pharmacokinetics and Pharmacodynamics After Kidney Transplantation

Autor: Pere Fontova, Helena Colom, Raül Rigo-Bonnin, Lisanne N. van Merendonk, Anna Vidal-Alabró, Nuria Montero, Edoardo Melilli, Maria Meneghini, Anna Manonelles, Josep M. Cruzado, Juan Torras, Josep Maria Grinyó, Oriol Bestard, Nuria Lloberas

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Introduction: Tacrolimus is the backbone immunosuppressant after solid organ transplantation. Tacrolimus has a narrow therapeutic window with large intra- and inter-patient pharmacokinetic variability leading to frequent over- and under-immunosuppres

Externí odkaz: https://doaj.org/article/919fc8842deb4744a8f2acf7f43d07ac

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Therapeutic Drug Monitoring of Lacosamide: Is 10 to 20 mg/L a Suitable Reference Range for Patients With Epilepsy?

Autor: Sara, Otero Torres, Roser, Juvany Roig, Mercè, Falip Centellas, Miriam, Casellas Gibert, Mónica, Estopiñá Antolí, Raül, Rigo Bonnin, Jacint Xavier, Sala-Padro, Ramón, Jódar Massanés

Publikováno v: Clinical Neuropharmacology. 46:39-42

The reference range for lacosamide (LCM) has been updated from 1 to 10 mg/L to 10 to 20 mg/L. Historically, LCM range was defined from trough-level measurements, but the newer ranges were obtained from peak-level measurements. The purpose of the stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102a3b047254cfd8eb3f00af0e78249e
https://doi.org/10.1097/wnf.0000000000000537

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EVEROLIMUS THERAPEUTIC DRUG MONITORING IN A CANCER RENAL CANCER PATIENT WHEN DOUBLE DRUG-DRUG INTERACTION IS DETECTED AND A REVIEW OF THE LITERATURE

Autor: Eduard Fort Casamartina, Carme Muñoz Sanchez, Raül Rigo-Bonnin, Núria Gonzalo Diego, Sara Otero Torres, Carmen Bleda Perez, Judith Prats Jimenez, Sandra Fontanals Martínez

Everolimus is an inhibitor of mammalian target of rapamycin (mTOR) widely used as an immunosuppressant in transplant patients. In transplantation setting, several recommendations for therapeutic drug monitoring are available, due to potential drug-dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54953d7a4c519b52fd6aef6f292ba9cb
https://doi.org/10.22541/au.167985365.54839192/v1

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Individual outcome prediction models for patients with COVID-19 based on their first day of admission to the intensive care unit

Autor: Xavier Solanich, Xose-Luís Pérez-Fernández, Luisa Corral-Ansa, Salvador Ventura-Pedret, Merce Gasa, Víctor-Daniel Gumucio-Sanguino, Enric Boza-Hernandez, Enrique Hernández-Jiménez, Joan Sabater-Riera, Raül Rigo-Bonnin, Maria Pons-Serra, MariPaz Fuset-Cabanes

Publikováno v: Clinical Biochemistry

Graphical abstract
Background Currently, good prognosis and management of critically ill patients with COVID-19 are crucial for developing disease management guidelines and providing a viable healthcare system. We aimed to propose individual out

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676df28e31e436803b36de030a57f34f
https://doi.org/10.1016/j.clinbiochem.2021.11.001

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Continuous Infusion of Piperacillin/Tazobactam and Meropenem in ICU Patients Without Renal Dysfunction: Are Patients at Risk of Underexposure?

Autor: Fe Tubau-Quintano, Jordi Carratalà, Víctor Daniel Gumucio-Sanguino, Xose L. Perez-Fernandez, Erika Esteve-Pitarch, Kristel Maisterra-Santos, Sara Cobo-Sacristán, Evelyn Shaw, Helena Colom-Codina, Joan Sabater-Riera, Raül Rigo-Bonnin, Ariadna Padullés-Zamora

Publikováno v: European Journal of Drug Metabolism and Pharmacokinetics. 46:527-538

Morbidity and mortality from serious infections are common in intensive care units (ICUs). The appropriateness of the antibiotic treatment is essential to combat sepsis. We aimed to evaluate pharmacokinetic/pharmacodynamic target attainment of merope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e79757ff741ee6cee70274235c0c36d0
https://doi.org/10.1007/s13318-021-00694-0

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Akademický článek

Guiding the starting dose of the once-daily formulation of tacrolimus in 'de novo' adult renal transplant patients: a population approach

Autor: Beatriz Fernández-Alarcón, Oscar Nolberger, Anna Vidal-Alabró, Raul Rigo-Bonnin, Josep M. Grinyó, Edoardo Melilli, Nuria Montero, Anna Manonelles, Ana Coloma, Alex Favà, Sergi Codina, Josep M. Cruzado, Helena Colom, Nuria Lloberas

Publikováno v: Frontiers in Pharmacology, Vol 15 (2024)

AimsThe once-daily extended-release tacrolimus formulation (ER-Tac) has demonstrated similar efficacy and safety to the twice-daily immediate-release formulation (IR-Tac), but few population-based pharmacokinetic models have been developed in de novo

Externí odkaz: https://doaj.org/article/e1e7a764787d4907916c5088a819c282

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