Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Raúl Torres-Ruíz"'
Autor:
Katrin Ottersbach, Alejandra Sanjuan-Pla, Raúl Torres-Ruíz, Clara Bueno, Talia Velasco-Hernández, Pablo Menendez
Publikováno v:
HemaSphere, Vol 2, Iss 4 (2018)
Externí odkaz:
https://doaj.org/article/9c92e7963b0a412c83ccbc1c1254af41
Autor:
Álvaro Gómez-Morón, Sergio Alegre-Gómez, Rocio Ramirez-Muñoz, Alicia Hernaiz-Esteban, Carlos Carrasco-Padilla, Camila Scagnetti, Óscar Aguilar-Sopeña, Marta García-Gil, Aldo Borroto, Raul Torres-Ruiz, Sandra Rodriguez-Perales, Francisco Sánchez-Madrid, Noa Beatriz Martín-Cófreces, Pedro Roda-Navarro
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Actin dynamics control early T-cell receptor (TCR) signalling during T-cell activation. However, the precise regulation of initial actin rearrangements is not completely understood. Here, we have investigated the regulatory role of the phosp
Externí odkaz:
https://doaj.org/article/33e816e2fa6646da9973b85120678fac
Autor:
Kang Zheng, Fengjie Hao, Sandra Medrano-Garcia, Chaobo Chen, Feifei Guo, Laura Morán-Blanco, Sandra Rodríguez-Perales, Raúl Torres-Ruiz, María Isabel Peligros, Javier Vaquero, Rafael Bañares, Manuel Gómez del Moral, José R. Regueiro, Eduardo Martínez-Naves, Mohamed Ramadan Mohamed, Rocío Gallego-Durán, Douglas Maya, Javier Ampuero, Manuel Romero-Gómez, Albert Gilbert-Ramos, Sergi Guixé-Muntet, Anabel Fernández-Iglesias, Jordi Gracia-Sancho, Mar Coll, Isabel Graupera, Pere Ginès, Andreea Ciudin, Jesús Rivera-Esteban, Juan M. Pericàs, María Dolores Frutos, Bruno Ramos Molina, José María Herranz, Matías A. Ávila, Yulia A. Nevzorova, Edgar Fernández-Malavé, Francisco Javier Cubero
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-12 (2023)
Abstract Progressive hepatic damage and fibrosis are major features of chronic liver diseases of different etiology, yet the underlying molecular mechanisms remain to be fully defined. N-RAS, a member of the RAS family of small guanine nucleotide-bin
Externí odkaz:
https://doaj.org/article/01a591f664c741c59cc9c983321052fd
Publikováno v:
e_Buah Biblioteca Digital Universidad de Alcalá
instname
instname
El neuroblastoma es una enfermedad infantil caracterizada por el desarrollo de tumores a partir de células cancerígenas del tejido nervioso de las glándulas suprarrenales. Existen marcadores genéticos para caracterizar, clasificar y diagnosticar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f1482af20a9cb95c65c1c4cf537943
https://hdl.handle.net/10017/41647
https://hdl.handle.net/10017/41647
CRISPR in Animals and Animal Models, Volume 152, the latest release in the Progress in Molecular Biology and Translational Science series, explores the genome editing CRISPR system in cells and animal models, its applications, the uses of the CRISPR
Autor:
Beatriz Martín-Adrados, Stefanie K. Wculek, Sergio Fernández-Bravo, Raúl Torres-Ruiz, Ana Valle-Noguera, Maria José Gomez-Sánchez, José Carlos Hernández-Walias, Frederico Moraes Ferreira, Ana María Corraliza, David Sancho, Vanesa Esteban, Sandra Rodriguez-Perales, Aránzazu Cruz-Adalia, Helder I. Nakaya, Azucena Salas, David Bernardo, Yolanda Campos-Martín, Elena Martínez-Zamorano, Diego Muñoz-López, Manuel Gómez del Moral, Francisco Javier Cubero, Richard S. Blumberg, Eduardo Martínez-Naves
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe Unfolded Protein Response, a mechanism triggered by the cell in response to Endoplasmic reticulum stress, is linked to inflammatory responses. Our aim was to identify novel Unfolded Protein Response-mechanisms that might be involved i
Externí odkaz:
https://doaj.org/article/59dfd819e60246a9be340bee3f602a6e
Autor:
Lucía Zhu, Diana Retana, Pedro García‐Gómez, Laura Álvaro‐Espinosa, Neibla Priego, Mariam Masmudi‐Martín, Natalia Yebra, Lauritz Miarka, Elena Hernández‐Encinas, Carmen Blanco‐Aparicio, Sonia Martínez, Cecilia Sobrino, Nuria Ajenjo, Maria‐Jesus Artiga, Eva Ortega‐Paino, Raúl Torres‐Ruiz, Sandra Rodríguez‐Perales, RENACER, Riccardo Soffietti, Luca Bertero, Paola Cassoni, Tobias Weiss, Javier Muñoz, Juan Manuel Sepúlveda, Pedro González‐León, Luis Jiménez‐Roldán, Luis Miguel Moreno, Olga Esteban, Ángel Pérez‐Núñez, Aurelio Hernández‐Laín, Oscar Toldos, Yolanda Ruano, Lucía Alcázar, Guillermo Blasco, José Fernández‐Alén, Eduardo Caleiras, Miguel Lafarga, Diego Megías, Osvaldo Graña‐Castro, Carolina Nör, Michael D Taylor, Leonie S Young, Damir Varešlija, Nicola Cosgrove, Fergus J Couch, Lorena Cussó, Manuel Desco, Silvana Mouron, Miguel Quintela‐Fandino, Michael Weller, Joaquín Pastor, Manuel Valiente, Adolfo de la Lama‐Zaragoza, Lourdes Calero‐Felix, Concepcion Fiaño‐Valverde, Pedro David Delgado‐López, Antonio Montalvo‐Afonso, Mar Pascual‐Llorente, Ángela Díaz‐Piqueras, SH Nam‐Cha, Cristina Barrena López, Gerard Plans Ahicart, Elena Martínez‐Saez, Santiago Ramón y Cajal, Pilar Nicolás
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 3, Pp 1-29 (2022)
Abstract We report a medium‐throughput drug‐screening platform (METPlatform) based on organotypic cultures that allows to evaluate inhibitors against metastases growing in situ. By applying this approach to the unmet clinical need of brain metast
Externí odkaz:
https://doaj.org/article/192ccb44b2e3449a849f6353de0e50dd
Autor:
Eva G. Álvarez, Jonas Demeulemeester, Paula Otero, Clemency Jolly, Daniel García-Souto, Ana Pequeño-Valtierra, Jorge Zamora, Marta Tojo, Javier Temes, Adrian Baez-Ortega, Bernardo Rodriguez-Martin, Ana Oitaben, Alicia L. Bruzos, Mónica Martínez-Fernández, Kerstin Haase, Sonia Zumalave, Rosanna Abal, Jorge Rodríguez-Castro, Aitor Rodriguez-Casanova, Angel Diaz-Lagares, Yilong Li, Keiran M. Raine, Adam P. Butler, Iago Otero, Atsushi Ono, Hiroshi Aikata, Kazuaki Chayama, Masaki Ueno, Shinya Hayami, Hiroki Yamaue, Kazuhiro Maejima, Miguel G. Blanco, Xavier Forns, Carmen Rivas, Juan Ruiz-Bañobre, Sofía Pérez-del-Pulgar, Raúl Torres-Ruiz, Sandra Rodriguez-Perales, Urtzi Garaigorta, Peter J. Campbell, Hidewaki Nakagawa, Peter Van Loo, Jose M. C. Tubio
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Hepatitis B virus (HBV) infection and DNA integration is a frequent cause of hepatocellular carcinoma (HCC), but the consequences of this process are not fully understood. Here the authors use whole-genome and long-read sequencing data from HCC patie
Externí odkaz:
https://doaj.org/article/9d6ae04fdf164e1683ea18005b4462b3
Autor:
Juan Miguel Baquero, Carlos Benítez-Buelga, Varshni Rajagopal, Zhao Zhenjun, Raúl Torres-Ruiz, Sarah Müller, Bishoy M. F. Hanna, Olga Loseva, Olov Wallner, Maurice Michel, Sandra Rodríguez-Perales, Helge Gad, Torkild Visnes, Thomas Helleday, Javier Benítez, Ana Osorio
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The most common oxidative DNA lesion is 8-oxoguanine which is mainly recognized and excised by the 8-oxoG DNA glycosylase 1 (OGG1), initiating the base excision repair (BER) pathway. Telomeres are particularly sensitive to oxidative stress (
Externí odkaz:
https://doaj.org/article/1b489d3921bb4809ad1aa6047fd0bc20
Autor:
Juan Miguel Baquero, Erik Marchena-Perea, Rocío Mirabet, Raúl Torres-Ruiz, Carmen Blanco-Aparicio, Sandra Rodríguez-Perales, Thomas Helleday, Carlos Benítez-Buelga, Javier Benítez, Ana Osorio
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundPARP1 plays a critical role in the base excision repair (BER) pathway, and PARP1 inhibition leads to specific cell death, through a synthetic lethal interaction, in the context of BRCA1/2 deficiency. To date, up to five different PARP inhib
Externí odkaz:
https://doaj.org/article/bd4acf3e7436440d9c1a0f93ca759fae