The complex HLA-E-nonapeptide in Behçet disease

Autor: Ángel Luís Castaño-Núñez, Marco-Antonio Montes-Cano, José-Raúl García-Lozano, Norberto Ortego-Centeno, Francisco José García-Hernández, Gerard Espinosa, Genaro Graña-Gil, Juan Sánchez-Bursón, María Rosa Juliá, Roser Solans, Ricardo Blanco, Ana-Celia Barnosi-Marín, Ricardo Gómez de la Torre, Patricia Fanlo, Mónica Rodríguez-Carballeira, Luis Rodríguez-Rodríguez, Teresa Camps, Santos Castañeda, Juan-Jose Alegre-Sancho, Javier Martín, María Francisca González-Escribano

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

IntroductionThe knowledge of the aetiology of Behçet disease (BD), an immune-mediated vasculitis, is limited. HLA-B, mainly HLA-B51, and HLA-A molecules are associated with disease, but the ultimate cause of this association remains obscure. There i

Externí odkaz: https://doaj.org/article/79971d0e6149449ab809dbe2149f9a0a

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Neonatal Screening for Sickle Cell Disease in Western Andalusia: Results and Lessons Learnt after 3 Years of Implementation

Autor: David Núñez-Jurado, Salvador Payán-Pernía, Ana I. Álvarez-Ríos, Margarita Jiménez-Jambrina, Inmaculada Concepcion Pérez-De-Soto, Antonio José Palma-Vallellano, Rocío Zapata-Bautista, José Carlos Hernández-Castellet, Mari Paz Garrastazul-Sánchez, Víctor Arqueros-Martínez, María del Mar Urbano-Ramos, Mohamed Abdelkader-Maanan, José Raúl García-Lozano, Carmen Delgado-Pecellín

Publikováno v: American Journal of Perinatology.

The aim of this study was to present the results obtained in the Newborn Screening Program (NSP) for sickle cell disease (SCD) in western Andalusia and the autonomous city of Ceuta in the first 3 years of implementation, and to describe the discrepan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9c46242467c0b39f4067baf2648f89
https://doi.org/10.1055/s-0042-1759646

Protein and functional isoform levels and genetic variants of the BAFF and APRIL pathway components in systemic lupus erythematosus

Autor: Pilar Ortiz-Aljaro, Marco Antonio Montes-Cano, José-Raúl García-Lozano, Virginia Aquino, Rosario Carmona, Javier Perez-Florido, Francisco José García-Hernández, Joaquín Dopazo, María Francisca González-Escribano

Systemic lupus erythematosus (SLE) is the prototype of an autoimmune disease. Belimumab, a monoclonal antibody targets BAFF, is the only biologic approved for SLE and active lupus nephritis. BAFF is a cytokine with a key-regulatory role in the B cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2200f8a0161dc0b9bc391a77d5ac5977
https://hdl.handle.net/10668/19615

Development and Validation of a Clinical-Genetic Risk Score to Predict Hepatic Encephalopathy in Patients With Liver Cirrhosis

Autor: Rubén Francés, María Carmen Rico, R. Millan, Javier Ampuero, Ángela Rojas, Rocío Gallego-Durán, Antonio Gil-Gómez, Manuel Romero-Gómez, Germán Soriano, Rocío Muñoz-Hernández, Raúl García-Lozano

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
AMERICAN JOURNAL OF GASTROENTEROLOGY
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Am J Gastroenterol

[Introduction] We aimed to define the impact of the genetic background on overt hepatic encephalopathy (HE) in patients with liver cirrhosis by developing a combined clinical-genetic risk score.
[Methods] Patients suffering from liver cirrhosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f8d11e83a05cbc69b7376579340f13
http://hdl.handle.net/10261/265389