Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Raúl Delgado-Morales"'
Autor:
Olga C. Jorge-Torres, Karolina Szczesna, Laura Roa, Carme Casal, Louisa Gonzalez-Somermeyer, Marta Soler, Cecilia D. Velasco, Pablo Martínez-San Segundo, Paolo Petazzi, Mauricio A. Sáez, Raúl Delgado-Morales, Stephane Fourcade, Aurora Pujol, Dori Huertas, Artur Llobet, Sonia Guil, Manel Esteller
Publikováno v:
Cell Reports, Vol 23, Iss 6, Pp 1665-1677 (2018)
Summary: Rett syndrome (RTT) is the second leading cause of mental impairment in girls and is currently untreatable. RTT is caused, in more than 95% of cases, by loss-of-function mutations in the methyl CpG-binding protein 2 gene (MeCP2). We propose
Externí odkaz:
https://doaj.org/article/bc1437b5be294926aba3171df569a526
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-18 (2017)
Abstract Ageing is the main risk factor for human neurological disorders. Among the diverse molecular pathways that govern ageing, epigenetics can guide age-associated decline in part by regulating gene expression and also through the modulation of g
Externí odkaz:
https://doaj.org/article/4c66a3121f3b4c2f9d60cbff5651940d
El conocimiento de la base genética de la existencia ha supuesto un gran cambio en nuestra concepción de la vida y la enfermedad. Pero en las últimas décadas, los estudios en torno a una serie de modificaciones reversibles en la estructura del ge
Autor:
Raul Delgado-Morales
This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation. By focusing on major human disorders such as Alzheimer's disease, cancer, and heart disorders
Autor:
Raul Delgado-Morales
Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the “physiological epigenome” are increasingly associated with human diseases. During the last decad
Autor:
Jose Vicente, Sanchez-Mut, Holger, Heyn, Enrique, Vidal, Raúl, Delgado-Morales, Sebastian, Moran, Sergi, Sayols, Juan, Sandoval, Isidre, Ferrer, Manel, Esteller, Johannes, Gräff
Publikováno v:
Synapse (New York, N.Y.). 71(6)
The brain's neocortex is anatomically organized into grey and white matter, which are mainly composed by neuronal and glial cells, respectively. The neocortex can be further divided in different Brodmann areas according to their cytoarchitectural org
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7340151e690bcfe335565d887ea13535
https://pubmed.ncbi.nlm.nih.gov/28105729
https://pubmed.ncbi.nlm.nih.gov/28105729
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
The locus coeruleus (LC), which contains the largest group of noradrenergic neurons in the central nervous system innervating the telencephalon, is an early and constantly vulnerable region to neurofibrillary tangle (NFT) pathology in aging and Alzhe
Externí odkaz:
https://doaj.org/article/f756081e8232437cac589ef526bd16d2