Protein-conformational diseases in childhood: Naturally-occurring hIAPP amyloid-oligomers and early β-cell damage in obesity and diabetes.

Autor: Nelly F Altamirano-Bustamante, Eulalia Garrido-Magaña, Eugenia Morán, Aurora Calderón, Karina Pasten-Hidalgo, Rosa Angélica Castillo-Rodríguez, Gerardo Rojas, Reyna Lara-Martínez, Edgar Leyva-García, Mateo Larralde-Laborde, Guadalupe Domíguez, Chiharu Murata, Yolanda Margarita-Vazquez, Rafael Payro, Manuel Barbosa, Alejandro Valderrama, Hortencia Montesinos, Alejandra Domínguez-Camacho, Víctor H García-Olmos, Regina Ferrer, Patricia G Medina-Bravo, Fernanda Santoscoy, Cristina Revilla-Monsalve, Luis Felipe Jiménez-García, Julio Morán, Jalil Villalobos-Alva, Mario Javier Villalobos, Raúl Calzada-León, Perla Altamirano, Myriam M Altamirano-Bustamante

Publikováno v: PLoS ONE, Vol 15, Iss 8, p e0237667 (2020)

Background and aimsThis is the first time that obesity and diabetes mellitus (DM) as protein conformational diseases (PCD) are reported in children and they are typically diagnosed too late, when β-cell damage is evident. Here we wanted to investiga

Externí odkaz: https://doaj.org/article/652cb12b4c944b90bca1b0fa52f7e6ce

Emotional dysfunction associated with diabetes in Mexican adolescents and young adults with type-1 diabetes Disfunción emocional asociada a diabetes en adolescentes y adultos jóvenes mexicanos con diabetes tipo 1

Autor: Israel Lerman-Garber, Consuelo Barrón-Uribe, Raúl Calzada-León, Moisés Mercado-Atri, Rafael Vidal-Tamayo, Silvia Quintana, María Elena Hernández, María de la Luz Ruiz-Reyes, Laura Elena Tamez-Gutiérrez, Elisa Nishimura-Meguro, Antonio R Villa

Publikováno v: Salud Pública de México, Vol 45, Iss 1, Pp 13-18 (2003)

OBJECTIVE: To assess the emotional dysfunction associated with diabetes in Mexican young individuals with type-1 diabetes. MATERIAL AND METHODS: A cross-sectional survey was conducted to perform a complete clinical and psychosocial evaluation of 93 c

Externí odkaz: https://doaj.org/article/5507b12e01594535b50fd59cf193dea5

Update of variants identified in the pancreatic β‐cell K ATP channel genes KCNJ11 and ABCC8 in individuals with congenital hyperinsulinism and diabetes

Autor: Jayne A L Houghton, Elisa De Franco, Raúl Calzada‐León, Siri Atma W. Greeley, Daniela del Gaudio, Annette Rønholt Larsen, Klaus Brusgaard, Elisa Nishimura-Meguro, Christine Bellanné-Chantelot, Bradley Harman, Sarah E. Flanagan, Amy E. Knight Johnson, Jean-Baptiste Arnoux, Cécile Saint-Martin, Pamela Bowman, Thomas W Laver, May Sanyoura, Sian Ellard, Lydia Aguilar-Bryan, Henrik Thybo Christesen

Publikováno v: Human Mutation
De Franco, E, Saint-Martin, C, Brusgaard, K, Knight Johnson, A E, Aguilar-Bryan, L, Bowman, P, Arnoux, J B, Larsen, A R, May, S, Greeley, S A W, Calzada-León, R, Harman, B, Houghton, J A L, Nishimura-Meguro, E, Laver, T W, Ellard, S, del Gaudio, D, Christesen, H T, Bellanné-Chantelot, C & Flanagan, S E 2020, ' Update of variants identified in the pancreatic β-cell K ATP channel genes KCNJ11 and ABCC8 in individuals with congenital hyperinsulinism and diabetes ', Human Mutation, vol. 41, no. 5, pp. 884-905 . https://doi.org/10.1002/humu.23995

The most common genetic cause of neonatal diabetes and hyperinsulinism is pathogenic variants in ABCC8 and KCNJ11. These genes encode the subunits of the β‐cell ATP‐sensitive potassium channel, a key component of the glucose‐stimulated insulin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c66ea5e0f0a34b21f6c3f814547fb269
https://doi.org/10.1002/humu.23995

Methodology for the development of the Clinical guideline for the diagnosis and treatment of precocious puberty

Autor: Margarita, Torres-Tamayo, Jessie N, Zurita-Cruz, Blanca E, Aguilar-Herrera, América L, Miranda-Lora, Raúl, Calzada-León, Aleida J, Rivera-Hernández, Marco A, Morales-Pérez, Miriam M, Padrón-Martínez, María L, Ruiz-Reyes, Leticia M, García-Morales, Consuelo, Barrón-Uribe, Sletza L, Arguinzoniz-Valenzuela, Mayra C, Torres-Castañeda, Lorena, Lizárraga-Paulin, Jorge A, Núñez-Hernández, Judith, Cornejo-Barrera, María T, Vidal-González, María R, Martínez-Alvarado, Elisa, Nishimura-Meguro, Luz E, Bravo-Ríos, Eulalia P, Garrido-Magaña, José A, Orozco-Morales, Patricia G, Medina-Bravo, Ninel, Coyote-Estrada, M Fernanda, Castilla-Peón

Publikováno v: Boletin medico del Hospital Infantil de Mexico. 77(Supl 1)

The Mexican Society of Pediatric Endocrinology presents recommendations for the diagnosis and treatment of precocious puberty (PP), a condition defined as the development of sexual characteristics due to an increase in pituitary gonadotropin secretio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::be03730ba74950432bb9dce195b71ecc
https://pubmed.ncbi.nlm.nih.gov/32614334

Diagnosis of precocious puberty: clinical guideline for the diagnosis and treatment of precocious puberty

Autor: América L, Miranda-Lora, Margarita, Torres-Tamayo, Jessie N, Zurita-Cruz, Blanca E, Aguilar-Herrera, Raúl, Calzada-León, Aleida J, Rivera-Hernández, Marco A, Morales-Pérez, Miriam M, Padrón-Martínez, María L, Ruiz-Reyes, Leticia M, García-Morales, Consuelo, Barrón-Uribe, Sletza L, Arguinzoniz-Valenzuela, Mayra C, Torres-Castañeda, Lorena, Lizárraga-Paulin, Jorge A, Núñez-Hernández, Judith, Cornejo-Barrera, María T, Vidal-González, María R, Martínez-Alvarado, Elisa, Nishimura-Meguro, Luz E, Bravo-Ríos, Eulalia P, Garrido-Magaña, José A, Orozco-Morales, Patricia G, Medina-Bravo, Ninel, Coyote-Estrada, M Fernanda, Castilla-Peón

Publikováno v: Boletin medico del Hospital Infantil de Mexico. 77(Supl 1)

The Mexican Society of Pediatric Endocrinology developed a clinical practice guide for the diagnosis and treatment of precocious puberty. This document presents recommendations related to the diagnosis of precocious puberty. The detailed description

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::96f7d1df17bd9af71e5f060d11878f1e
https://pubmed.ncbi.nlm.nih.gov/32614333