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Akademický článek

A systematic assessment of mitochondrial function identified novel signatures for drug-induced mitochondrial disruption in cells.

Autor: Li N; Department of Comparative Biology and Safety Sciences, Amgen, Amgen Court West 1201, Seattle, Washington 98119., Oquendo E; MitoSciences Inc., Eugene, Oregon 97403., Capaldi RA; MitoSciences Inc., Eugene, Oregon 97403., Robinson JP; Purdue University Cytometry Laboratories, Department of Basic Medical Sciences, Purdue University, West Lafayette, Indiana 47907., He YD; Department of Comparative Biology and Safety Sciences, Amgen, Amgen Court West 1201, Seattle, Washington 98119., Hamadeh HK; Department of Comparative Biology and Safety Sciences, Amgen, 1 Amgen Center Dr, Thousand Oaks, California 91320-1799., Afshari CA; Department of Comparative Biology and Safety Sciences, Amgen, 1 Amgen Center Dr, Thousand Oaks, California 91320-1799., Lightfoot-Dunn R; Department of Comparative Biology and Safety Sciences, Amgen, 1 Amgen Center Dr, Thousand Oaks, California 91320-1799., Narayanan PK; Department of Comparative Biology and Safety Sciences, Amgen, Amgen Court West 1201, Seattle, Washington 98119 padman@amgen.com.

Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2014 Nov; Vol. 142 (1), pp. 261-73. Date of Electronic Publication: 2014 Aug 27.

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Akademický článek

Uniform nomenclature for the mitochondrial contact site and cristae organizing system.

Autor: Pfanner N; Institut für Biochemie und Molekularbiologie, Zentrum für Biochemie und Molekulare Zellforschung, and 2 BIOSS Centre for Biological Signalling Studies, Universität Freiburg, 79104 Freiburg, Germany., van der Laan M, Amati P, Capaldi RA, Caudy AA, Chacinska A, Darshi M, Deckers M, Hoppins S, Icho T, Jakobs S, Ji J, Kozjak-Pavlovic V, Meisinger C, Odgren PR, Park SK, Rehling P, Reichert AS, Sheikh MS, Taylor SS, Tsuchida N, van der Bliek AM, van der Klei IJ, Weissman JS, Westermann B, Zha J, Neupert W, Nunnari J

Publikováno v: The Journal of cell biology [J Cell Biol] 2014 Mar 31; Vol. 204 (7), pp. 1083-6.

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Akademický článek

ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import.

Autor: Li Q; Department of Neurology, Hope Center for Neurological Disorders, The Washington University School of Medicine, St Louis, MO 63110, USA., Vande Velde C, Israelson A, Xie J, Bailey AO, Dong MQ, Chun SJ, Roy T, Winer L, Yates JR, Capaldi RA, Cleveland DW, Miller TM

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2010 Dec 07; Vol. 107 (49), pp. 21146-51. Date of Electronic Publication: 2010 Nov 15.

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Akademický článek

Novel antibody-based strategies for the rapid diagnosis of mitochondrial disease and dysfunction.

Autor: Marusich MF; MitoSciences, Inc., 1850 Millrace Dr., Eugene, OR 97403, USA., Murray J, Xie J, Capaldi RA

Publikováno v: The international journal of biochemistry & cell biology [Int J Biochem Cell Biol] 2009 Oct; Vol. 41 (10), pp. 2081-8. Date of Electronic Publication: 2009 May 19.

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Akademický článek

Isolated deficiencies of OXPHOS complexes I and IV are identified accurately and quickly by simple enzyme activity immunocapture assays.

Autor: Willis JH; MitoSciences, Inc. Eugene, OR 97403, USA., Capaldi RA, Huigsloot M, Rodenburg RJ, Smeitink J, Marusich MF

Publikováno v: Biochimica et biophysica acta [Biochim Biophys Acta] 2009 May; Vol. 1787 (5), pp. 533-8. Date of Electronic Publication: 2008 Nov 10.

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Akademický článek

Lateral-flow immunoassay for detecting drug-induced inhibition of mitochondrial DNA replication and mtDNA-encoded protein synthesis.

Autor: Nadanaciva S; MitoSciences Inc., Eugene, OR 97403, USA. sashi.nadanaciva@pfizer.com, Willis JH, Barker ML, Gharaibeh D, Capaldi RA, Marusich MF, Will Y

Publikováno v: Journal of immunological methods [J Immunol Methods] 2009 Mar 31; Vol. 343 (1), pp. 1-12. Date of Electronic Publication: 2009 Jan 17.

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Akademický článek

Screening for the metabolic basis of neurodegeneration: developing a focused proteomic approach.

Autor: Murray J; Mitosciences Inc, Eugene, OR, USA., Capaldi RA

Publikováno v: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2008 Dec; Vol. 1147, pp. 348-57.

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Akademický článek

Monitoring oxidative and nitrative modification of cellular proteins; a paradigm for identifying key disease related markers of oxidative stress.

Autor: Murray J; Mitosciences Inc, Eugene OR 97403-2095, USA. jmurray@mitosciences.com, Oquendo CE, Willis JH, Marusich MF, Capaldi RA

Publikováno v: Advanced drug delivery reviews [Adv Drug Deliv Rev] 2008 Oct-Nov; Vol. 60 (13-14), pp. 1497-503. Date of Electronic Publication: 2008 Jul 04.

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Akademický článek

Mitochondrial oxidative phosphorylation protein levels in peripheral blood mononuclear cells correlate with levels in subcutaneous adipose tissue within samples differing by HIV and lipoatrophy status.

Autor: Shikuma CM; Hawaii AIDS Clinical Research Program, John A. Burns School of Medicine, University of Hawaii-Manoa, Honolulu, Hawaii 96816, USA. shikuma@hawaii.edu, Gerschenson M, Chow D, Libutti DE, Willis JH, Murray J, Capaldi RA, Marusich M

Publikováno v: AIDS research and human retroviruses [AIDS Res Hum Retroviruses] 2008 Oct; Vol. 24 (10), pp. 1255-62.

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