Zobrazeno 1 - 10
of 229
pro vyhledávání: '"RYUICHI KIKKAWA"'
Autor:
Takaaki Nakamura, Alison Fox-Robichaud, Ryuichi Kikkawa, Astunori Kashiwagi, Hideto Kojima, Mineko Fujimiya, Norman C.W. Wong
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 9, Pp 1709-1718 (1999)
Apolipoprotein (apo)A-I alone or as a component of high density lipoprotein particles has antiatherogenic properties. The age-dependent decline in abundance of this protein may underlie the higher risk for developing occlusive coronary artery disease
Externí odkaz:
https://doaj.org/article/524efa26957c41adb5fdbd8ad0f1cf60
Autor:
Yasuo Ohashi, Atsushi Araki, Junya Ako, Kenzo Oba, Hirohito Sone, Nobuhiro Yamada, Tadasumi Nakano, Hisayuki Miura, Koichi Yokono, Ryuichi Kikkawa, Atsunori Kashiwagi, Takashi Sakurai, Satoshi Iimuro, Hiroyuki Umegaki, Katsuya Iijima, Hideki Ito, Yukio Yoshimura, Koichi Kozaki, Hiroshi Nakano
Publikováno v:
Geriatrics & Gerontology International. 12:18-28
Aims: To evaluate the association of low-density lipoprotein, high-density lipoprotein and non-high-density lipoprotein cholesterol with the risk of stroke, diabetes-related vascular events and mortality in elderly diabetes patients. Methods: This st
Autor:
Nobuhiro Yamada, Hideki Ito, Takashi Sakurai, Koichi Yokono, Hisayuki Miura, Ryuichi Kikkawa, Kenzo Oba, Hirohito Sone, Katsuya Iijima, Atsushi Araki, Yasuo Ohashi, Satoshi Iimuro, Junya Ako, Hiroshi Nakano, Yukio Yoshimura, Koichi Kozaki, Tadasumi Nakano, Atsunori Kashiwagi, Hiroyuki Umegaki
Publikováno v:
Geriatrics & Gerontology International. 12:7-17
Aim: To evaluate long-term, multiple risk factor intervention on physical, psychological and mental prognosis, and development of complications and cardiovascular disease in elderly type 2 diabetes patients. Methods: Our randomized, controlled, multi
Autor:
Keiji Isshiki, Shin-ichi Araki, Hiroshi Maegawa, Ryuichi Kikkawa, Atsunori Kashiwagi, Yasuo Kida, Daisuke Koya, Takashi Uzu, Masakazu Haneda, Shinji Kume, Atsushi Yamauchi
Publikováno v:
Journal of the American Society of Hypertension. 6:124-131
There is little evidence regarding the target blood pressure level in patients with type 2 diabetes mellitus without overt proteinuria.We followed 608 Japanese patients with type 2 diabetes without apparent cardiovascular disease and overt proteinuri
Autor:
Jiro Nakamura, Takayoshi Toyota, Yoshiyuki Ohno, Yasuhiko Iwamoto, Ryuichi Kikkawa, Masato Kasuga, Nigishi Hotta
Publikováno v:
Journal of Diabetes Investigation. 1:66-76
We collated and analysed data from hospital records regarding the cause of death of 18,385 patients with diabetes who died in 282 medical institutions throughout Japan over the 10-year period between 1991 and 2000. Autopsy was carried out in 1750 cas
Autor:
Torben Hansen, Michiaki Kubo, Annelli Sandbæk, Knut Borch-Johnsen, Shiro Maeda, Oluf Pedersen, Tatsuhiko Tsunoda, Torben Jørgensen, Daniel P.K. Ng, Johan Holmkvist, Tetsuya Babazono, Hiroyuki Unoki, Naoyuki Kamatani, Yasuhiko Iwamoto, Hiroshi Hirose, Momoko Horikoshi, Gitte Andersen, Siti Nurbaya, Atsushi Takahashi, Takahisa Kawaguchi, Torsten Lauritzen, Ryuichi Kikkawa, Yusuke Nakamura, Atsunori Kashiwagi, Kazuo Hara, Matsuhiko Hayashi, Takashi Kadowaki, Ryuzo Kawamori, Kohei Kaku, E. Shyong Tai
Publikováno v:
Unoki, H, Takahashi, A, Kawaguchi, T, Hara, K, Horikoshi, M, Ng, D P K, Holmkvist, J, Borch-Johnsen, K, Jørgensen, T, Sandbaek, A, Lauritzen, T, Hansen, T, Nurbaya, S, Tsunoda, T, Kubo, M, Babazono, T, Hirose, H, Hayashi, M, Iwamoto, Y, Kashiwagi, A, Kaku, K, Kawamori, R, Tai, E S, Pedersen, O, Kamatani, N, Kadowaki, T, Kikkawa, R, Nakamura, Y & Maeda, S 2008, ' SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations ', Nature Genetics, vol. 40, no. 9, pp. 1098-102 . https://doi.org/10.1038/ng.208
Udgivelsesdato: 2008-Sep We conducted a genome-wide association study using 207,097 SNP markers in Japanese individuals with type 2 diabetes and unrelated controls, and identified KCNQ1 (potassium voltage-gated channel, KQT-like subfamily, member 1)
Autor:
Toshiro Sugimoto, Hiroyuki Mori, Takashi Sato, Masakazu Haneda, Daisuke Koya, Motohide Isono, Atsunori Kashiwagi, Ken Inoki, Baofeng Yang, Ryuichi Kikkawa, Baoliang Guo, Satoshi Akiba, Keizo Kanasaki
Publikováno v:
Kidney International. 68(3):972-984
MAPK/AP-1-dependent regulation of PAI-1 gene expression by TGF-β in rat mesangial cells. Background Receptor-regulated Smads and/or mitogen-activated protein kinases (MAPKs) are involved in transforming growth factor-β (TGF-β)-nduced expression of
Autor:
Aritoshi Iida, Shiro Maeda, Yusuke Nakamura, Atsunori Kashiwagi, Tetsuya Babazono, Yasuhiko Iwamoto, Yoshihiro Kawamura, Tatsuhiko Tsunoda, Masafumi Matsuda, Masahito Imanishi, Akio Kanazawa, T. Iiizumi, Akihiro Sekine, Koichi Kawai, Tomoaki Fujioka, Yasutaka Tanaka, Ryuichi Kikkawa, Kohei Kaku, Ryuzo Kawamori
Publikováno v:
Diabetologia. 48:1315-1322
Although genetic susceptibility plays an important role in the pathogenesis of type 2 diabetes, most of the genes that influence susceptibility to type 2 diabetes have yet to be identified. Krüppel-like transcription factors are known to play import
Autor:
Kohei Kaku, Tetsuya Babazono, Yasuhiko Iwamoto, Akio Kanazawa, Shiro Maeda, Yusuke Nakamura, Atsunori Kashiwagi, Yasushi Tanaka, Tatsuhiko Tsunoda, Syuuichi Tsukada, Ryuzo Kawamori, Masafumi Matsuda, Ryuichi Kikkawa, Akihiro Sekine, Atsushi Takahashi
Publikováno v:
The American Journal of Human Genetics. 75(5):832-843
Recent reports have suggested that WNT signaling is an important regulator for adipogenesis or insulin secretion and might be involved in the pathogenesis of type 2 diabetes. To investigate possible roles of the WNT genes in conferring susceptibility