Zobrazeno 1 - 10
of 48
pro vyhledávání: '"RW Lord"'
Autor:
Kartik Kumar, Thomas Scoones, RW Lord, Andrew M. Jones, Michael R. Loebinger, Laura Macfarlane
Publikováno v:
Clin Med (Lond)
Bronchiectasis is a heterogeneous and increasingly prevalent chronic pulmonary disease that is associated with significant morbidity. In this review, we outline how patients with bronchiectasis may present clinically and describe an approach to its d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4781ddccab931cf135e3304761a1a67e
https://pubmed.ncbi.nlm.nih.gov/34862215
https://pubmed.ncbi.nlm.nih.gov/34862215
Autor:
Valentyn Moskalenko, Nathan D. Pfeifer, Brett Haumann, Edmund J. Moran, Elad Kaufman, Glenn Crater, David A. Lombardi, David L. Bourdet, RW Lord, Ashley Woodcock, Jacky Woo, Dave Singh, Maxim Bogus, Tuan Nguyen, Rajeev Saggar, Emily Y. Weng
BackgroundLung-targeted anti-inflammatory therapy could potentially improve outcomes in patients with COVID-19. The novel inhaled pan-Janus kinase (JAK) inhibitor TD-0903 was designed to optimise delivery to the lungs while limiting systemic exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40423d33da822e5548c57baa4f6ff857
https://doi.org/10.1101/2021.03.09.21252944
https://doi.org/10.1101/2021.03.09.21252944
Autor:
RW Lord, Andrew M. Jones, Peter J. Barry, Dipesh H. Vasant, Peter J. Whorwell, Jane Wych, A.L. Brennan, Sharon Archbold, Jacky Smith
Publikováno v:
Posters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d603cb552cd6e1a8c362b178e9ca8aa
https://doi.org/10.1136/gutjnl-2020-bsgcampus.421
https://doi.org/10.1136/gutjnl-2020-bsgcampus.421
Autor:
RW Lord, Elad Kaufman, Nathan D. Pfeifer, Glenn Crater, Edmund J. Moran, Ashley Woodcock, Rajeev Saggar, Jacky Woo, Maxim Bogus, Dave Singh, David L. Bourdet, Tuan Nguyen, Emily Y. Weng, Valentyn Moskalenko, Brett Haumann, David A. Lombardi
Publikováno v:
Singh, D, Bogus, M, Moskalenko, V, Lord, R, Moran, E J, Crater, G D, Bourdet, D L, Pfeifer, N D, Woo, J, Kaufman, E, Lombardi, D A, Weng, E Y, Nguyen, T, Woodcock, A, Haumann, B & Saggar, R 2021, ' A phase 2 multiple ascending dose study of the inhaled pan-JAK inhibitor nezulcitinib (TD-0903) in severe COVID-19 ', European Respiratory Journal, vol. 58, no. 4, 2100673 . https://doi.org/10.1183/13993003.00673-2021
The inhaled lung-selective pan-JAK inhibitor nezulcitinib appears generally well tolerated in hospitalised patients with severe #COVID-19, with trends for improved oxygenation and clinical status, shortened hospitalisation, and fewer deaths versus pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d23c90bcf978bfeadaa1468946ed9e
https://doi.org/10.1183/13993003.00673-2021
https://doi.org/10.1183/13993003.00673-2021
Autor:
Joseph Elborn, RW Lord, Andrew M. Jones, A.J. Lee, Gisli G. Einarsson, Michael M. Tunney, B. Bianco, Peter J. Whorwell
Publikováno v:
Cystic fibrosis and bronchiectasis: updates and controversies.
Background It has been proposed that the increased amounts of gastro-oesophageal reflux seen in cystic fibrosis (CF) patients can lead to reflux aspiration, which in turn may influence the lung microbiome. The aim of this study was to assess microbia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc11378b8e824dcd81e6365127e5bb4c
https://doi.org/10.1136/thorax-2019-btsabstracts2019.385
https://doi.org/10.1136/thorax-2019-btsabstracts2019.385
Autor:
Gisli G. Einarsson, RW Lord, Andrew M. Jones, Joseph Elborn, A.J. Lee, Michael M. Tunney, Jacky Smith
Publikováno v:
Cystic fibrosis and bronchiectasis: updates and controversies.
Background Historically during microbiological observations sputum has been thought to represent the ‘lower’ airway or the lung environment. However, during expectoration sputum passes through the oropharynx, potentially resulting in contaminatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::743f7a8f5e1706f91ca4ccf379090b8c
https://doi.org/10.1136/thorax-2019-btsabstracts2019.393
https://doi.org/10.1136/thorax-2019-btsabstracts2019.393
Autor:
Robert J. Beynon, Victoria M. Harman, Paul S. McNamara, R.E. Maher, RW Lord, B. Bianco, Andrew M. Jones, Peter J. Whorwell, Jacky Smith
Publikováno v:
Biomarkers and treatments in cystic fibrosis.
Introduction There is potential for protein biomarkers to assist with clinical decision making in cystic fibrosis (CF) patients, such as when to commence and cease antibiotic therapy. Several small proteomic studies in CF populations have identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85ced588a85ed94335a52990b61f3d41
https://doi.org/10.1136/thorax-2019-btsabstracts2019.24
https://doi.org/10.1136/thorax-2019-btsabstracts2019.24
Autor:
Victoria M. Harman, B. Bianco, Paul S. McNamara, Rosemary Maher, Robert J. Beynon, Jacky Smith, RW Lord, Andrew M. Jones
Publikováno v:
Cystic fibrosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b0231930b283eba992b6f4b7322c1ae
https://doi.org/10.1183/13993003.congress-2019.pa974
https://doi.org/10.1183/13993003.congress-2019.pa974
Autor:
A.J. Lee, Michael M. Tunney, Gisli G. Einarsson, Stuart Elborn, RW Lord, Andrew M. Jones, Jackie Smith
Publikováno v:
Journal of Cystic Fibrosis. 19:S78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::805226c9de3b84121a724a6253973188
https://doi.org/10.1016/s1569-1993(20)30416-1
https://doi.org/10.1016/s1569-1993(20)30416-1
Autor:
Michael M. Tunney, Gisli G. Einarsson, Stuart Elborn, RW Lord, A.J. Lee, Andrew M. Jones, Jackie Smith
Publikováno v:
Journal of Cystic Fibrosis. 19:S79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b204779af0c012360555151805c1ff16
https://doi.org/10.1016/s1569-1993(20)30420-3
https://doi.org/10.1016/s1569-1993(20)30420-3