Zobrazeno 1 - 10
of 252
pro vyhledávání: '"RW Carrell"'
Autor:
Daly M, Dj, Perry, Db, Bruce, Pl, Harper, Robert Tait, Id, Walker, Ee, Mayne, Hm, Daly, Brown K, Rw, Carrell
Publikováno v:
Europe PubMed Central
The genetic basis of Type I antithrombin deficiency has been investigated in six unrelated kindred with positive histories of thrombosis using a PCR amplification/direct sequencing approach. Four frameshift mutations, all introducing premature transl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::884ddf4d2bacb9f007d51623569e3607
https://pubmed.ncbi.nlm.nih.gov/8735803
https://pubmed.ncbi.nlm.nih.gov/8735803
Publikováno v:
Blood. 69:1275-1279
Antithrombin III (AT-III) Rouen is a hereditary abnormal antithrombin with normal progressive inhibitory activity and reduced heparin cofactor activity. It was isolated from the plasma of a woman who suffered a sudden idiopathic sensorineural hearing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be1cb1e844ff70c96b5a110a15f2a439
https://doi.org/10.1182/blood.v69.5.1275.bloodjournal6951275
https://doi.org/10.1182/blood.v69.5.1275.bloodjournal6951275
Autor:
H L Gibson, RW Carrell, P Pemberton, IC Bathurst, Peter M. George, S Rosenberg, PJ Barr, RA Hallewell
Publikováno v:
Blood. 73(2)
Both congenital and acquired antithrombin-III (AT-III) deficiencies are amenable to replacement therapy. We describe two antithrombins produced by recombinant DNA techniques from human alpha 1-antitrypsin (alpha 1AT) cDNA in yeast. Alteration of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dded9b2eb4534c7e27bfcfbc708a7f5
https://pubmed.ncbi.nlm.nih.gov/2644977
https://pubmed.ncbi.nlm.nih.gov/2644977
Autor:
Dj, Perry, Me, Daly, Robert Tait, Id, Walker, Brown K, Nj, Beauchamp, Fe, Preston, Gyde H, Pl, Harper, Rw, Carrell
Publikováno v:
Europe PubMed Central
Thirty-one individuals from 18 unrelated families with antithrombin deficiency have been identified as having a single point mutation within codon 384 (13268 GCA--TCA) resulting in an alanine to serine substitution. Six families (11 individuals) were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::61dc70d7b57c68b1598a03b511c87a82
http://europepmc.org/abstract/med/9493570
http://europepmc.org/abstract/med/9493570
Autor:
Nj, Beauchamp, Rn, Pike, Daly M, Butler L, Makris M, Tim Dafforn, Zhou A, Hl, Fitton, Fe, Preston, Ir, Peake, Rw, Carrell
Publikováno v:
Europe PubMed Central
The inherent variability of conformational diseases is demonstrated by two families with different mutations of the same conserved aminoacid in antithrombin. Threonine 85 underlies the opening of the main beta-sheet of the molecule and its replacemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e45f4f9696f0ade92045fd5c17e641c6
http://europepmc.org/abstract/med/9763552
http://europepmc.org/abstract/med/9763552
Autor:
Shu Z; Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Wan J; Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Read RJ; Department of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom., Carrell RW; Department of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom., Zhou A; Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Publikováno v:
Frontiers in cardiovascular medicine [Front Cardiovasc Med] 2021 Mar 18; Vol. 8, pp. 645123. Date of Electronic Publication: 2021 Mar 18 (Print Publication: 2021).
Autor:
Carrell RW; Emeritus Professor of Haematology, Trinity College, University of Cambridge, Cambridge CB2 1TQ, UK; 1986 - 2003: Professor of Haematology, University of Cambridge & Head of Clinical Haematology, Addenbrooke's Hospital, Cambridge, UK; 1978- 1986: Professor of Molecular Pathology, Pathology Department, Christchurch School of Medicine, University of Otago, New Zealand. Electronic address: rwc1000@cam.ac.uk.
Publikováno v:
Journal of clinical epidemiology [J Clin Epidemiol] 2020 Nov; Vol. 127, pp. 223-224.
Heparin Blocks the Inhibition of Tissue Kallikrein 1 by Kallistatin through Electrostatic Repulsion.
Autor:
Ma L; Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China., Wu J; Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China., Zheng Y; Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China., Shu Z; Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China., Wei Z; Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China., Sun Y; Randall Division of Cell & Molecular Biophysics, Faculty of Life Sciences & Medicine, King's College London, New Hunt's House, Guy's Campus, London SE1 1UL, UK., Carrell RW; Department of Haematology, University of Cambridge, Cambridge CB2 0XY, UK., Zhou A; Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Publikováno v:
Biomolecules [Biomolecules] 2020 May 28; Vol. 10 (6). Date of Electronic Publication: 2020 May 28.
Autor:
Yan Y; From the Department of Haematology, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, United Kingdom and., Zhou A; the Hongqiao International Institute of Medicine, Shanghai Tongren Hospital/Faculty of Basic Medicine, Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China aiwu.zhou@googlemail.com awz20@shsmu.edu.cn., Carrell RW; From the Department of Haematology, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, United Kingdom and., Read RJ; From the Department of Haematology, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, United Kingdom and rjr27@cam.ac.uk.
Publikováno v:
The Journal of biological chemistry [J Biol Chem] 2019 Feb 15; Vol. 294 (7), pp. 2353-2364. Date of Electronic Publication: 2018 Dec 18.
Autor:
Dahabiyeh LA; Department of Pharmaceutical Sciences, School of Pharmacy, The University of Jordan, Amman, 11942, Jordan.; Centre for Analytical Bioscience, Advanced Materials and Healthcare Technologies Division, School of Pharmacy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK., Tooth D; School of Life Sciences, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, NG7 2RD, UK., Carrell RW; Department of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK., Read RJ; Department of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK., Yan Y; Department of Clinical Biochemistry, Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK., Pipkin FB; Department of Obstetrics and Gynaecology, City Hospital, University of Nottingham, Nottingham, NG5 1PB, UK., Barrett DA; Centre for Analytical Bioscience, Advanced Materials and Healthcare Technologies Division, School of Pharmacy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK. David.Barrett@nottingham.ac.uk.
Publikováno v:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2019 Jan; Vol. 411 (2), pp. 427-437. Date of Electronic Publication: 2018 Nov 21.