Zobrazeno 1 - 10
of 104
pro vyhledávání: '"RUNZHI ZHU"'
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundHepatoblastoma has an unsatisfactory prognosis, and traditional chemotherapy has strong side effects. Dihydromyricetin is a flavonoid extracted from a woody vine of the genus Serpentine in the family Vitaceae, with effects such as preventin
Externí odkaz:
https://doaj.org/article/eaee87bbd74b49a6890b1d7f06641973
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
BackgroundRenal cell carcinoma (RCC) was sex-hormone responsive, and clinical trials using progesterone significantly reduced the incidence of distal metastasis after radical nephrectomy. Recently membrane-bound progesterone receptors (mPRs) were dis
Externí odkaz:
https://doaj.org/article/b5acb69c33754dd0b091a629ef27b4a7
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundHepcidin is a polypeptide hormone mainly produced by hepatocytes to modulate systemic iron balance. A drastic downregulation of the hepcidin gene was found in liver cancers. However, there is a paucity of information about the clinical sign
Externí odkaz:
https://doaj.org/article/00650277fcbe48cda07b8cf68db1139d
JS-K, a nitric oxide donor, induces autophagy as a complementary mechanism inhibiting ovarian cancer
Autor:
Bin Liu, Xiaojie Huang, Yifang Li, Weiguo Liao, Mingyi Li, Yi Liu, Rongrong He, Du Feng, Runzhi Zhu, Hiroshi Kurihara
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-15 (2019)
Abstract Background Ovarian cancer (OC) is the second most frequent gynecological cancer and is associated with a poor prognosis because OC progression is often asymptoma-tic and is detected at a late stage. There remains an urgent need for novel tar
Externí odkaz:
https://doaj.org/article/7ba8c225e2704ebcbeb5f7412d0de88d
Autor:
Runzhi Zhu, Yanjie Tu, Jingxia Chang, Haixia Xu, Jean C. Li, Wang Liu, Ahn-Dao Do, Yuxia Zhang, Jinhu Wang, Benyi Li
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundLiver cancer is a leading cause of cancer death worldwide, and novel prognostic factor is needed for early detection and therapeutic responsiveness monitoring. The orphan nuclear receptor NR0B2 was reported to suppress liver cancer developm
Externí odkaz:
https://doaj.org/article/a7e69a8767fc480c9168f6431255554f
Autor:
Yuqian Yan, Jian An, Yinhui Yang, Di Wu, Yang Bai, William Cao, Linlin Ma, Junhui Chen, Zhendong Yu, Yundong He, Xin Jin, Yunqian Pan, Tao Ma, Shangqian Wang, Xiaonan Hou, Saravut John Weroha, R Jeffrey Karnes, Jun Zhang, Jennifer J Westendorf, Liguo Wang, Yu Chen, Wanhai Xu, Runzhi Zhu, Dejie Wang, Haojie Huang
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 4, Pp 1-20 (2018)
Abstract AKT‐mTOR and androgen receptor (AR) signaling pathways are aberrantly activated in prostate cancer due to frequent PTEN deletions or SPOP mutations. A clinical barrier is that targeting one of them often activates the other. Here, we demon
Externí odkaz:
https://doaj.org/article/fe77ca9d430249659565d1429f2f9aba
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1383 (2021)
Progesterone-induced rapid non-genomic signaling events have been confirmed through several membrane progesterone receptors (mPR). Some mPRs were reported to correlate with cancer progression and patient prognosis. In this study, we conducted a compr
Externí odkaz:
https://doaj.org/article/70b4b764010a443a9ce7a259b96d5f46
Autor:
Xianglong Xu, Tao Gong, Yong Zhang, Chengbin Wu, Yao Jie Xie, Harry HX Wang, Runzhi Zhu, Wentao Li, Libin An, Yong Zhao
Publikováno v:
Tobacco Induced Diseases, Vol 13, Iss September (2015)
Background China is the largest producer and consumer of tobacco in the world. Considering the constantly growing urban proportion, persuasive tobacco control measures are important in urban communities. Television, as one of the most pervasive mass
Externí odkaz:
https://doaj.org/article/9d3275c6072c43a59b1599ee2aa1ceb8
Autor:
Lianggui Jiang, Qingyu Zhang, Hao Ren, Sheng Ma, CaiJie Lu, Bin Liu, Jie Liu, Jian Liang, Mingyi Li, Runzhi Zhu
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124994 (2015)
Chemotherapy is an effective weapon in the battle against cancer. Nedaplatin (NDP) is an improved platinum-containing drug with lower cytotoxicity than other similar drugs. However, the repeated use of NDP results in substantial hepatocyte damage as
Externí odkaz:
https://doaj.org/article/d523e7d2f89248f398adc79aefe8b07c
Autor:
Shixing Wu, Bin Liu, Qingyu Zhang, Jie Liu, Wei Zhou, Chang Wang, Mingyi Li, Shiting Bao, Runzhi Zhu
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e76886 (2013)
Dihydromyricetin (DHM) is a major active ingredient of flavonoids compounds. It exhibited anticancer activity and induced apoptosis in human hepatocellular carcinoma HepG2 cells according to our previous data. In this study, we investigated whether p
Externí odkaz:
https://doaj.org/article/6250ec867fe64c069f4a2929b443d5df