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Akademický článek

Chinese medicine PaBing-II protects human iPSC-derived dopaminergic neurons from oxidative stress

Autor: Shouhai Wu, Cuiping Rong, Ruishan Lin, Kaiyuan Ji, Tongxiang Lin, Weimin Chen, Wei Mao, Yang Xu

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

BackgroundPaBing-II Formula (PB-II) is a traditional Chinese medicine for treating Parkinson’s disease (PD). However, owing to the complexity of PB-II and the difficulty in obtaining human dopaminergic neurons (DAn), the mechanism of action of PB-I

Externí odkaz: https://doaj.org/article/153f9207006b4ae0969a684d734cb4ca

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Investigation of antitumor mechanism of the chiral ruthenium complex Λ-[Ru(phen) 2 p-MOPIP] 2+ in human gastric cancer MGC-803 cells

Autor: Xiaonian Zhang, Zhujuan Huang, Jie Liu, Ruishan Lin, Shaofeng Wu, Ning Su

Publikováno v: Inorganic Chemistry Communications. 72:1-6

There has been a vast increase in telomerase inhibition research over the past several years, which was demonstrated as an attractive anti-tumor strategy. Our previous study found that the chiral ruthenium complex, [Ru(phen)2p-MOPIP]2 + (Phen = 1,10-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a2fa18751940722c91456c0fba341544
https://doi.org/10.1016/j.inoche.2016.07.018

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Upregulation of glutamate metabolism by BYHWD in cultured astrocytes following oxygen-glucose deprivation/reoxygenation in part depends on the activation of p38 MAPK

Autor: Ruixian Guo, Ruishan Lin, Wei Liu, Peng Yu, Lequan Zhou, Xiaoying Li, Li Guan, Wenting Ding, Jianchao Guo

Recent studies have demonstrated that Buyang Huanwu Decoction (BYHWD) decreased glutamate levels subsequent to cerebral ischemia. Glutamate transporter-1 (GLT-1) and glutamine synthetase (GS), which are located in astrocytes, mainly contribute to glu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4466bfc706134f29c8f0eddd403540c
https://europepmc.org/articles/PMC5450553/

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Buyang Huanwu decoction increases the expression of glutamate transporter-1 and glutamate synthetase in association with PACAP-38 following focal ischemia

Autor: Lequan Zhou, Li Guan, Ruishan Lin, Peng Yu, Wei Liu, Wenting Ding

Publikováno v: Biomedical reports. 3(5)

The neuroprotective role of Buyang Huanwu decoction (BYHWD) in focal ischemia is associated with decreasing glutamate concentration. However, the mechanisms are not fully understood. The present study aimed to explore whether glutamate transporter-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce04abdf082673c7d03b1b8de6cd3788
https://pubmed.ncbi.nlm.nih.gov/26405540

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