Zobrazeno 1 - 10
of 45
pro vyhledávání: '"RU-FU CHEN"'
Publikováno v:
Molecular Medicine Reports. 16:4980-4986
The long noncoding RNA, homeobox transcript antisense RNA (Hotair), has been demonstrated to have an important role in regulating various biological processes in various cancers, including hepatocellular carcinoma (HCC). However, the importance of Ho
Autor:
Shangyou Zheng, Wenzhu Li, Xiaohui Zhao, Yue Zhao, Huilin Ye, Wenwei Pan, Lusheng Wei, Ru-Fu Chen, Zhihua Li, Tianwen Nong, Changhao Chen, Zhiqiang Fu
Publikováno v:
Journal of Cellular and Molecular Medicine
Hypoxia‐inducible factor‐2α (HIF‐2α) plays an important role in increasing cancer progression and distant metastasis in a variety of tumour types. We aimed to investigate its biological function and clinical significance in human pancreatic d
Publikováno v:
Oncology Letters. 13:2198-2206
Considering mucin 1-variable number tandem repeat (MUC1-VNTRn) as a novel target for pancreatic cancer immunotherapy, the present study aimed to screen and identify the pVAX1-MUC1-VNTRn DNA vaccine with the strongest immunogenicity. Following constru
Autor:
Jie Wang, Ya-Jing Chen, Xiaoping Liu, Xi Ou, Ru-Fu Chen, Qing-jia Ou, Li-Xuan Wu, Yong Xie, Pei-Kai Tian, Zewei Lin, Hua Ye, Jun Min, Chao Liu
Publikováno v:
International Journal of Medical Sciences
Objectives: To investigate the expression of transcriptional factors (TFs) T-bet, GATA-3, RORγt and FOXP in peripheral blood mononuclear cells (PBMC) of patients with hepatocellular carcinoma (HCC) and to evaluate the correlation between the imbalan
Publikováno v:
Oncology Letters.
Long non-coding RNA HOX transcript antisense RNA (HOTAIR) has been demonstrated to exhibit oncogenic activity in several types of cancer, including hepatocellular carcinoma (HCC). However, the association between HOTAIR and HCC multidrug resistance r
Publikováno v:
Hepatology research : the official journal of the Japan Society of Hepatology. 47(6)
Aberrant expression of Snail, a mediator of epithelial-mesenchymal transition (EMT), is crucial for cancer invasiveness and metastasis. Although hepatitis C virus (HCV) core protein has been implicated in hepatocarcinogenesis, the relationship betwee
Autor:
Qiaofang Liao, Di Cheng, Zhihua Li, Qing Lin, Bing Zeng, Jia-Jia Zhou, Ning Guo, Ru‑Fu Chen, Quan Bo Zhou
Publikováno v:
Journal of Cellular Biochemistry. 113:3419-3426
Previous studies showed that transient transfection of HCVc improved hTERT expression in hepatoma cell lines and it was noteworthy that phosphorylated signal transducer and activator of transcription 3 (pSTAT3) and DNA methyltransferases (DNMTs) were
Publikováno v:
Carbohydrate Polymers. 83:1499-1506
Hydrophilic amylopectin was modified by grafting hydrophobic poly (lactic acid) chains. The 13C NMR and X-ray diffraction (XRD) analyses confirmed the modification reaction. For the resultant amphiphilic derivatives with various grafting yields, thei
Autor:
Yuqing Lan, Huaisheng Zhou, Liqun Yang, Jizhou Fan, Xiang Cai, Liang-zheng Cheng, Ru-fu Chen, Li-Ming Zhang, Hui Guo
Publikováno v:
Acta Pharmacologica Sinica. 31:1625-1634
To investigate the ability of drug-loaded N,O-carboxymethyl chitosan (CMCS) hydrogels to modulate wound healing after glaucoma filtration surgery. The drug-loaded CMCS hydrogels were in situ synthesized using genipin as the crosslinker in the presenc
Publikováno v:
Journal of Gastroenterology and Hepatology. 25:1315-1320
UNLABELLED In an earlier study, we found that hepatitis C virus core protein, HCV-C, participated in the malignant transformation of HCV-C transfected normal human biliary epithelial (hBE) cells by activating telomerase. Here we further investigated