Zobrazeno 1 - 10
of 49
pro vyhledávání: '"RT-QuIC assay"'
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Prion diseases are rapidly progressive, invariably fatal, transmissible neurodegenerative disorders associated with the accumulation of the amyloidogenic form of the prion protein in the central nervous system (CNS). In humans, prion diseases are hig
Externí odkaz:
https://doaj.org/article/607b833ff69b49488b34ca60c791d22a
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Prion diseases, synucleinopathies and tauopathies are neurodegenerative disorders characterized by deposition of abnormal protein aggregates in brain and other tissues. These aggregates consist of misfolded forms of prion, α-synuclein (αSyn), or ta
Externí odkaz:
https://doaj.org/article/5df5f6ef9a154dabb2b6c3d09bddb2ed
Autor:
Thi-Thu-Trang Dong, Akio Akagi, Toshiaki Nonaka, Takehiro Nakagaki, Ban Mihara, Masaki Takao, Yasushi Iwasaki, Noriyuki Nishida, Katsuya Satoh
Publikováno v:
Neurobiology of Disease, Vol 159, Iss , Pp 105504- (2021)
Background: The neuropathology of sporadic Creutzfeldt–Jakob disease (sCJD) is usually investigated using formalin-fixed and formic acid-treated brain tissue. However, formalin and formic acid treatment can interfere with immunostaining of abnormal
Externí odkaz:
https://doaj.org/article/27f56fdc9bb7432c983b4875971edbda
Publikováno v:
Pathogens, Vol 10, Iss 6, p 750 (2021)
The possibilities for diagnosing prion diseases have shifted significantly over the last 10 years. The RT-QuIC assay option has been added for neuropsychiatric symptoms, supporting biomarkers and final post-mortem confirmation. Samples of brain homog
Externí odkaz:
https://doaj.org/article/862522c0c3f944ff90aa53b2b9b4cccc
Autor:
Weiguanliu Zhang, Xiangzhu Xiao, Mingxuan Ding, Jue Yuan, Aaron Foutz, Mohammed Moudjou, Tetsuyuki Kitamoto, Jan P. M. Langeveld, Li Cui, Wen-Quan Zou
Publikováno v:
Pathogens, Vol 10, Iss 5, p 513 (2021)
Prion is an infectious protein (PrPSc) that is derived from a cellular glycoprotein (PrPC) through a conformational transition and associated with a group of prion diseases in animals and humans. Characterization of proteinase K (PK)-resistant PrPSc
Externí odkaz:
https://doaj.org/article/6fd16ee78a354f4f852a06da72790eb3
Autor:
Thi-Thu-Trang Dong, Katsuya Satoh
Publikováno v:
Pathogens, Vol 10, Iss 3, p 305 (2021)
The misfolding of proteins such as the prion protein, α-synuclein, and tau represents a key initiating event for pathogenesis of most common neurodegenerative disorders, and its presence correlates with infectivity. To date, the diagnosis of these d
Externí odkaz:
https://doaj.org/article/0d11b7a484a0431ab8027e2be4d834bd
Autor:
DONG, THI THU TRANG
Background: The neuropathology of sporadic Creutzfeldt–Jakob disease (sCJD) is usually investigated using formalin-fixed and formic acid-treated brain tissue. However, formalin and formic acid treatment can interfere with immunostaining of abnormal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1e53eaf857b898199d1e6722c6542849
https://nagasaki-u.repo.nii.ac.jp/records/27699
https://nagasaki-u.repo.nii.ac.jp/records/27699
Autor:
Gianluigi Zanusso, Elisa Colaizzo, Anna Poleggi, Carlo Masullo, Raffaello Romeo, Sergio Ferrari, Matilde Bongianni, Michele Fiorini, Dorina Tiple, Luana Vaianella, Marco Sbriccoli, Flavia Porreca, Michele Equestre, Maurizio Pocchiari, Franco Cardone, Anna Ladogana
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 18; Pages: 10210
Genetic Creutzfeldt–Jakob disease (gCJD) associated with the V180I mutation in the prion protein (PrP) gene (PRNP) in phase with residue 129M is the most frequent cause of gCJD in East Asia, whereas it is quite uncommon in Caucasians. We report on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8680df6a747a0d4f2ef599e0469a7fa
http://hdl.handle.net/11562/1076993
http://hdl.handle.net/11562/1076993
Autor:
Akio Akagi, Takehiro Nakagaki, Noriyuki Nishida, Toshiaki Nonaka, Katsuya Satoh, Masaki Takao, Ban Mihara, Thi-Thu-Trang Dong, Yasushi Iwasaki
Publikováno v:
Neurobiology of Disease, Vol 159, Iss, Pp 105504-(2021)
Background The neuropathology of sporadic Creutzfeldt–Jakob disease (sCJD) is usually investigated using formalin-fixed and formic acid-treated brain tissue. However, formalin and formic acid treatment can interfere with immunostaining of abnormal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53424cd7d0f521332a852f149dbc9e1
https://pubmed.ncbi.nlm.nih.gov/34509607
https://pubmed.ncbi.nlm.nih.gov/34509607
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