Zobrazeno 1 - 10
of 336
pro vyhledávání: '"RS Chaganti"'
Publikováno v:
Blood. 86:2892-2899
The t(11;14)(q13;q32) translocation, which juxtaposes the BCL1 oncogene with the Ig heavy chain locus, has been associated with an uncommon subtype of non-Hodgkin's lymphoma (NHL) termed mantle cell lymphoma (MCL). To date, no molecular marker that s
Publikováno v:
Blood. 83:2611-2618
Deletions of the long arm of chromosome 6 have been described in acute and chronic lymphocytic leukemia (ALL and CLL) and prolymphocytic leukemia (PLL), and have been associated with t(14;18)(q32;q21) in non- Hodgkin's lymphoma (NHL). Of 55 cases of
Autor:
K Offit, NZ Parsa, G Gaidano, DA Filippa, D Louie, D Pan, SC Jhanwar, R Dalla- Favera, RS Chaganti
Publikováno v:
Blood. 82:2157-2162
Commonly observed in lymphoid neoplasms, deletions of 6q have been correlated with histologic and clinical subsets of non-Hodgkin's lymphoma (NHL). Our recent analysis of loss of heterozygosity of 6q loci in NHL showed two regions of minimal molecula
Autor:
Gianluca GAIDANO, Rs, Hauptschein, Nz, Parsa, Offit K, Ph, Rao, Lenoir G, Dm, Knowles, Rs, Chaganti, Dalla-Favera R
Publikováno v:
Europe PubMed Central
The recurrent loss of genetic material from a specific chromosomal region in a given tumor type suggests the presence of a tumor- suppressor gene, the loss or inactivation of which may be relevant for tumorigenesis. In this study, we provide molecula
Autor:
M Ladanyi, K Offit, NZ Parsa, MR Condon, N Chekka, JP Murphy, DA Filippa, SC Jhanwar, R Dalla-Favera, RS Chaganti
Publikováno v:
Blood. 79:2124-2130
The presence of the translocation t(8;14)(q24;q32) has not been well described in follicular lymphoma (FL). In a consecutive series of 278 karyotypically abnormal non-Hodgkin's lymphomas (NHL), six patients with FL showing a t(8;14) without a t(14;18
Publikováno v:
Blood. 75:1346-1355
Serial cytogenetic studies were performed on 64 patients with chronic myelogenous leukemia (CML) after T cell-depleted allogeneic bone marrow transplantation (BMT). Forty patients with CML in chronic phase (CP) received cytoreduction followed by BMT
Autor:
Vg, Dyomin, Nallasivam Palanisamy, Ko, Lloyd, Dyomina K, Sc, Jhanwar, Houldsworth J, Rs, Chaganti
Publikováno v:
Europe PubMed Central
The band 1q21 is among the most common sites affected by chromosomal translocations in lymphoid, myeloid, epithelial, and sarcomatous lesions. In non-Hodgkin's lymphoma (NHL), translocations and duplications affecting this chromosomal site are freque
Autor:
Gianluca GAIDANO, Nz, Parsa, Tassi V, Della-Latta P, Rs, Chaganti, Dm, Knowles, Dalla-Favera R
Publikováno v:
Europe PubMed Central
Lymphoma represents a major source of morbidity and mortality among AIDS patients. AIDS-associated non-Hodgkin lymphomas (AIDS-NHL) are almost invariably B-cell derived, are classified as high or intermediate grade lymphomas, and display three main h
Autor:
Offit K, Nz, Parsa, Gianluca GAIDANO, Da, Filippa, Louie D, Pan D, Sc, Jhanwar, Dalla-Favera R, Rs, Chaganti
Publikováno v:
Europe PubMed Central
Commonly observed in lymphoid neoplasms, deletions of 6q have been correlated with histologic and clinical subsets of non-Hodgkin's lymphoma (NHL). Our recent analysis of loss of heterozygosity of 6q loci in NHL showed two regions of minimal molecula
Publikováno v:
Blood. 77(5)
The configuration of the MYC gene in diffuse large cell lymphomas (DLCL) with translocations involving band 8q24 [t(8q24)] has not been systematically studied. We collected cytogenetic and clinical data on 171 consecutive cases of DLCL, including cle