Zobrazeno 1 - 10
of 486
pro vyhledávání: '"RRM1"'
Autor:
Linjin Fan, Yulong Wang, Hongxin Huang, Zequn Wang, Chudan Liang, Xiaofeng Yang, Pengfei Ye, Jingyan Lin, Wendi Shi, Yuandong Zhou, Huijun Yan, Zhenyu Long, Zhongyi Wang, Linna Liu, Jun Qian
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTEbola virus (EBOV) belongs to Filoviridae family possessing single-stranded negative-sense RNA genome, which is a serious threat to human health. Nowadays, no therapeutics have been proven to be successful in efficiently decreasing the mortal
Externí odkaz:
https://doaj.org/article/416fb82cdfd4451e8dc53507b3df886f
Autor:
Li Ma, Xiaolei Tao, Wangtian Wang, Jintang Jiao, Yuanyuan Pu, Gang Yang, Lijun Liu, Yan Fang, Junyan Wu, Wancang Sun
Publikováno v:
BMC Plant Biology, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background The RNA recognition motif (RRM) is primarily engaged in the processing of mRNA and rRNA following gene transcription as well as the regulation of RNA transport; it is critical in preserving RNA stability. Results In this study, we
Externí odkaz:
https://doaj.org/article/8aab3dd5ba0d4468b3c97a7f0562ed54
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8595 (2024)
Ribonucleotide reductase (RNR) is the rate-limiting enzyme in the synthesis of deoxyribonucleotides and the target of multiple chemotherapy drugs, including gemcitabine. We previously identified that inhibition of RNR in Ewing sarcoma tumors upregula
Externí odkaz:
https://doaj.org/article/44f2127aeecf4e698c2b3617c6715ff1
Akademický článek
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Akademický článek
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Publikováno v:
International Journal of General Medicine, Vol Volume 15, Pp 2607-2620 (2022)
Guochao Mao, Changyou Shan, Weimiao Li, Baobao Liang, Li Ma, Shuqun Zhang Department of Oncology, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, 710000, People’s Republic of ChinaCorrespondence: Shuqun Zhang, Depar
Externí odkaz:
https://doaj.org/article/1a0dbc93447443e281cefc8092cbc722
Akademický článek
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Autor:
Wendy Muñoz-Montaño, Sae Muñiz-Hernández, Alejandro Avilés-Salas, Rodrigo Catalán, Luis Lara-Mejía, Suraj Samtani-Bassarmal, Andres F. Cardona, Jorge Mendoza-Desión, Daniel Hernández-Cueto, Altagracia Maldonado, Guillermina Baay-Guzmán, Sara Huerta-Yepes, Oscar Arrieta
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Malignant Pleural Mesothelioma (MPM) is a rare but aggressive neoplasia that usually presents at advanced stages. Even though some advances have been achieved in the management of patients with MPM, this malignancy continuous to i
Externí odkaz:
https://doaj.org/article/4bb5fae34e0d4cf4a0b815d426954ba7
Publikováno v:
Heliyon, Vol 8, Iss 6, Pp e09643- (2022)
Purpose: This study aimed to detect the expression levels of topoisomerase IIα (TOP2A), ribonucleotide reductase catalytic subunit M1 (RRM1),c-erbB-2 (HER2) and excision repair cross complementing group 1 (ERCC1) in non-muscular invasive bladder can
Externí odkaz:
https://doaj.org/article/9e2c0911475243169e06b2a4ee2a20fc
Autor:
Jiarong Zhou, Linshi Zhang, Huilin Zheng, Wenhao Ge, Yu Huang, Yingcai Yan, Xiaohu Zhou, Wei Zhu, Yang Kong, Yuan Ding, Weilin Wang
Publikováno v:
Cancer Medicine, Vol 9, Iss 3, Pp 1115-1130 (2020)
Abstract Gemcitabine (GEM) alone and GEM‐based chemotherapy are the preferred regimens for treating advanced unresectable and metastatic pancreatic cancer (PC). However, these treatments have limited efficacy due to acquired resistance of cancer ce
Externí odkaz:
https://doaj.org/article/df25b615a550416794146ecdaeb94d30