Zobrazeno 1 - 10
of 133
pro vyhledávání: '"RP Witherspoon"'
Autor:
PJ Martin, BJ Nelson, FR Appelbaum, C Anasetti, HJ Deeg, JA Hansen, GB McDonald, RA Nash, KM Sullivan, RP Witherspoon, PJ Scannon, N Friedmann, R Storb
Publikováno v:
Blood. 88:824-830
Acute graft-versus-host disease (GVHD) is most often treated with high dose glucocorticoids, but less than half of patients have durable overall improvement. Previous phase I and phase II studies suggested that treatment with a CD5-specific immunotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e727e91e160b5e3bf38abd25691dd9a
https://doi.org/10.1182/blood.v88.3.824.bloodjournal883824
https://doi.org/10.1182/blood.v88.3.824.bloodjournal883824
Autor:
Hp, Kiem, Gb, Mcdonald, David Myerson, Cl, Spurgeon, Hj, Deeg, Je, Sanders, Doney K, Fr, Appelbaum, Km, Sullivan, Rp, Witherspoon, Storb R
Publikováno v:
Europe PubMed Central
Between 1971 and 1989 we have treated 19 patients with hepatitis-associated aplastic anemia by marrow transplantation from their HLA-identical siblings following conditioning with 200 mg/kg cyclophosphamide (Cy) administered over a period of 4 days.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::097d2eec0c93976cea72f7cf51432140
https://pubmed.ncbi.nlm.nih.gov/9118304
https://pubmed.ncbi.nlm.nih.gov/9118304
Publikováno v:
Blood. 69:308-315
Upon activation, B cells express growth and differentiation receptors that permit them to proliferate and differentiate. The aim of this study is to define the nature of the intrinsic B cell defects found in marrow recipients using assays for B cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e944893499fa122d945d26c568c83bbd
https://doi.org/10.1182/blood.v69.1.308.bloodjournal691308
https://doi.org/10.1182/blood.v69.1.308.bloodjournal691308
Publikováno v:
Blood. 59:844-850
Immunoglobulin secretion was studied in 37 patients between 19 and 106 days after allogeneic HLA-identical (30 patients), allogeneic one HLA- haplotype-identical (three patients), syngeneic (three patients), or autologous (one patient) marrow graftin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9088bb0ab4b823e15798f890c73d7063
https://doi.org/10.1182/blood.v59.4.844.bloodjournal594844
https://doi.org/10.1182/blood.v59.4.844.bloodjournal594844
Autor:
PJ Martin, JA Hansen, CD Buckner, JE Sanders, HJ Deeg, P Stewart, FR Appelbaum, R Clift, A Fefer, RP Witherspoon
Publikováno v:
Blood. 66(3)
We report results of a pilot study designed to evaluate the effects of in vitro depletion of T lymphocytes from donor marrow in patients receiving HLA-identical marrow grafts for treatment of hematologic malignancies. Twenty patients aged 31 to 50 ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e546bedf9da39f6f1a38ff67aa213637
https://pubmed.ncbi.nlm.nih.gov/3896348
https://pubmed.ncbi.nlm.nih.gov/3896348
Autor:
R Storb, RL Prentice, M Banaji, RP Witherspoon, KM Sullivan, P Stewart, JE Sanders, M Mason, K Doney, J Deeg, RA Clift, CD Buckner, FR Appelbaum, ED Thomas
Publikováno v:
Blood. 61(4)
The present study in patients with aplastic anemia was undertaken to determine whether exposure of recipients to donor blood products 24 hr before preparation with cyclophosphamide (1) enhanced the rate of sustained engraftment of marrow from HLA-ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6abeca01f42d8cad87fd6475b8b810bf
https://pubmed.ncbi.nlm.nih.gov/6338970
https://pubmed.ncbi.nlm.nih.gov/6338970
Autor:
Km, Sullivan, Rp, Witherspoon, Storb R, Weiden P, Nancy Flournoy, Dahlberg S, Hj, Deeg, Je, Sanders, Kc, Doney, Fr, Appelbaum
Publikováno v:
Europe PubMed Central
We conducted a randomized, double-blind comparison of prednisone and placebo (group I) v prednisone and azathioprine (1.5 mg/kg/day) (group II) as early treatment of extensive chronic graft-v-host disease (GVHD). Patients with platelet counts less th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49dad9fcf7d6eae96b8f9ee73f956948
https://pubmed.ncbi.nlm.nih.gov/3042041
https://pubmed.ncbi.nlm.nih.gov/3042041
Autor:
KM Sullivan, HM Shulman, R Storb, PL Weiden, RP Witherspoon, GB McDonald, MM Schubert, K Atkinson, ED Thomas
Publikováno v:
Blood. 57(2)
Fifty-two of 175 (30%) survivors of allogeneic marrow transplantation developed chronic graft-versus-hose diseases (GVHD). Five with limited chronic GVHD had an indolent clinical course with involvement of only the skin and liver. Forty-seven with ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b70cddc90232f7466655426f9c2d3130
https://pubmed.ncbi.nlm.nih.gov/7004534
https://pubmed.ncbi.nlm.nih.gov/7004534
Autor:
KM Sullivan, RP Witherspoon, R Storb, HJ Deeg, S Dahlberg, JE Sanders, FR Appelbaum, KC Doney, P Weiden, C Anasetti
Publikováno v:
Blood. 72(2)
Therapy of chronic graft-v-host disease (GVHD) has been unsatisfactory in patients with platelet counts less than 100,000/microL. Survival at 5 years after marrow transplant is only 26% in such patients treated with trimethoprim-sulfamethoxazole (TMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538a9730925d0cc07a58913296a89f42
https://pubmed.ncbi.nlm.nih.gov/3042042
https://pubmed.ncbi.nlm.nih.gov/3042042
Autor:
R Storb, KC Doney, ED Thomas, F Appelbaum, CD Buckner, RA Clift, HJ Deeg, BW Goodell, R Hackman, JA Hansen, J Sanders, K Sullivan, PL Weiden, RP Witherspoon
Publikováno v:
Blood. 59(2)
Sixty-five multiply transfused patients with severe aplastic anemia were given cyclophosphamide followed by grafts anemia were given cyclophosphamide followed by grafts from HLA-identical siblings. The effect of the administration of viable donor buf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94517e52353f48042e10a9d99f82e49
https://pubmed.ncbi.nlm.nih.gov/7034811
https://pubmed.ncbi.nlm.nih.gov/7034811