Dual Role of microRNA-146a in Experimental Inflammation in Human Pulmonary Epithelial and Immune Cells and Expression in Inflammatory Lung Diseases.

Autor: Gronau L; Department of Pediatrics, Division of Pneumology, Allergology, Infectious Diseases and Gastroenterology, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany., Duecker RP; Department of Pediatrics, Division of Pneumology, Allergology, Infectious Diseases and Gastroenterology, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany., Jerkic SP; Department of Pediatrics, Division of Pneumology, Allergology, Infectious Diseases and Gastroenterology, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany., Eickmeier O; Department of Pediatrics, Division of Pneumology, Allergology, Infectious Diseases and Gastroenterology, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany., Trischler J; Department of Pediatrics, Division of Pneumology, Allergology, Infectious Diseases and Gastroenterology, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany., Chiocchetti AG; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany., Blumchen K; Department of Pediatrics, Division of Pneumology, Allergology, Infectious Diseases and Gastroenterology, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany., Zielen S; Respiratory Research Institute, Medaimun GmbH, 60596 Frankfurt am Main, Germany., Schubert R; Department of Pediatrics, Division of Pneumology, Allergology, Infectious Diseases and Gastroenterology, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 13; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 13.

In Cerebellar Atrophy of 12-Month-Old ATM-Null Mice, Transcriptome Upregulations Concern Most Neurotransmission and Neuropeptide Pathways, While Downregulations Affect Prominently Itpr1, Usp2 and Non-Coding RNA.

Autor: Reichlmeir M; Goethe University Frankfurt, University Hospital, Clinic of Neurology, Exp. Neurology, Heinrich Hoffmann Str. 7, 60590 Frankfurt am Main, Germany., Canet-Pons J; Goethe University Frankfurt, University Hospital, Clinic of Neurology, Exp. Neurology, Heinrich Hoffmann Str. 7, 60590 Frankfurt am Main, Germany., Koepf G; Goethe University Frankfurt, University Hospital, Clinic of Neurology, Exp. Neurology, Heinrich Hoffmann Str. 7, 60590 Frankfurt am Main, Germany., Nurieva W; Transposition and Genome Engineering, Research Centre of the Division of Hematology, Gene and Cell Therapy, Paul Ehrlich Institute, 63225 Langen, Germany., Duecker RP; Division of Pediatrics, Pulmonology, Allergology, Infectious Diseases and Gastroenterology, Children's Hospital, University Hospital, Goethe-University, 60590 Frankfurt am Main, Germany., Doering C; Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, 60590 Frankfurt am Main, Germany., Abell K; Cell Signaling Technology, Inc., Danvers, MA 01923, USA., Key J; Goethe University Frankfurt, University Hospital, Clinic of Neurology, Exp. Neurology, Heinrich Hoffmann Str. 7, 60590 Frankfurt am Main, Germany., Stokes MP; Cell Signaling Technology, Inc., Danvers, MA 01923, USA., Zielen S; Division of Pediatrics, Pulmonology, Allergology, Infectious Diseases and Gastroenterology, Children's Hospital, University Hospital, Goethe-University, 60590 Frankfurt am Main, Germany.; Respiratory Research Institute, Medaimun GmbH, 60596 Frankfurt am Main, Germany., Schubert R; Division of Pediatrics, Pulmonology, Allergology, Infectious Diseases and Gastroenterology, Children's Hospital, University Hospital, Goethe-University, 60590 Frankfurt am Main, Germany., Ivics Z; Transposition and Genome Engineering, Research Centre of the Division of Hematology, Gene and Cell Therapy, Paul Ehrlich Institute, 63225 Langen, Germany., Auburger G; Goethe University Frankfurt, University Hospital, Clinic of Neurology, Exp. Neurology, Heinrich Hoffmann Str. 7, 60590 Frankfurt am Main, Germany.

Publikováno v: Cells [Cells] 2023 Oct 03; Vol. 12 (19). Date of Electronic Publication: 2023 Oct 03.

Liver Assessment in Patients with Ataxia-Telangiectasia: Transient Elastography Detects Early Stages of Steatosis and Fibrosis.

Autor: Donath H; Department for Children and Adolescents, Division of Allergology, Pulmonology and Cystic Fibrosis, University Hospital Frankfurt, Goethe University, Frankfurt, Germany., Wölke S; Department for Children and Adolescents, Division of Allergology, Pulmonology and Cystic Fibrosis, University Hospital Frankfurt, Goethe University, Frankfurt, Germany., Knop V; Department of Internal Medicine 1, University Hospital Frankfurt, Goethe University, Frankfurt, Germany., Heß U; Department for Children and Adolescents, Division of Allergology, Pulmonology and Cystic Fibrosis, University Hospital Frankfurt, Goethe University, Frankfurt, Germany., Duecker RP; Department for Children and Adolescents, Division of Allergology, Pulmonology and Cystic Fibrosis, University Hospital Frankfurt, Goethe University, Frankfurt, Germany., Trischler J; Department for Children and Adolescents, Division of Allergology, Pulmonology and Cystic Fibrosis, University Hospital Frankfurt, Goethe University, Frankfurt, Germany., Poynard T; Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Hepatology Department, Frankfurt, Germany., Schubert R; Department for Children and Adolescents, Division of Allergology, Pulmonology and Cystic Fibrosis, University Hospital Frankfurt, Goethe University, Frankfurt, Germany., Zielen S; Department for Children and Adolescents, Division of Allergology, Pulmonology and Cystic Fibrosis, University Hospital Frankfurt, Goethe University, Frankfurt, Germany.

Publikováno v: Canadian journal of gastroenterology & hepatology [Can J Gastroenterol Hepatol] 2023 Mar 11; Vol. 2023, pp. 2877350. Date of Electronic Publication: 2023 Mar 11 (Print Publication: 2023).

Correction to: Neurofilament Light Chain is a Biomarker of Neurodegeneration in Ataxia Telangiectasia.

Autor: Donath H; Division of Allergology, Pulmonology and Cystic Fibrosis, Department for Children and Adolescents, Goethe University, Frankfurt, Germany. Helena.Donath@kgu.de., Woelke S; Division of Allergology, Pulmonology and Cystic Fibrosis, Department for Children and Adolescents, Goethe University, Frankfurt, Germany., Schubert R; Division of Allergology, Pulmonology and Cystic Fibrosis, Department for Children and Adolescents, Goethe University, Frankfurt, Germany., Kieslich M; Division of Pediatric Neurology, Department for Children and Adolescents, Goethe University, Frankfurt, Germany., Theis M; Division of Pediatric Neurology, Department for Children and Adolescents, Goethe University, Frankfurt, Germany., Auburger G; Experimental Neurology, Medical School, Goethe University, Frankfurt, Germany., Duecker RP; Division of Allergology, Pulmonology and Cystic Fibrosis, Department for Children and Adolescents, Goethe University, Frankfurt, Germany., Zielen S; Division of Allergology, Pulmonology and Cystic Fibrosis, Department for Children and Adolescents, Goethe University, Frankfurt, Germany.

Publikováno v: Cerebellum (London, England) [Cerebellum] 2022 Feb; Vol. 21 (1), pp. 48.

Simple Measurement of IgA Predicts Immunity and Mortality in Ataxia-Telangiectasia.

Autor: Zielen S; Division of Allergology, Pulmonology and Cystic Fibrosis, Department for Children and Adolescents, Goethe University, Frankfurt, Germany., Duecker RP; Division of Allergology, Pulmonology and Cystic Fibrosis, Department for Children and Adolescents, Goethe University, Frankfurt, Germany. RuthPia.Duecker@kgu.de., Woelke S; Division of Allergology, Pulmonology and Cystic Fibrosis, Department for Children and Adolescents, Goethe University, Frankfurt, Germany., Donath H; Division of Allergology, Pulmonology and Cystic Fibrosis, Department for Children and Adolescents, Goethe University, Frankfurt, Germany., Bakhtiar S; Division for Stem Cell Transplantation, Immunology and Intensive Care Unit, Department for Children and Adolescents, Goethe University, Frankfurt, Germany., Buecker A; Division of Allergology, Pulmonology and Cystic Fibrosis, Department for Children and Adolescents, Goethe University, Frankfurt, Germany., Kreyenberg H; Division for Stem Cell Transplantation, Immunology and Intensive Care Unit, Department for Children and Adolescents, Goethe University, Frankfurt, Germany., Huenecke S; Division for Stem Cell Transplantation, Immunology and Intensive Care Unit, Department for Children and Adolescents, Goethe University, Frankfurt, Germany., Bader P; Division for Stem Cell Transplantation, Immunology and Intensive Care Unit, Department for Children and Adolescents, Goethe University, Frankfurt, Germany., Mahlaoui N; Pediatric Immunology-Hematology and Rheumatology Unit, French National Reference Center for Primary Immune Deficiencies (CEREDIH), Necker Children's University Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France., Ehl S; Institute for Immunodeficiency, Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., El-Helou SM; Institute for Immunodeficiency, Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; RESIST - Cluster of Excellence 2155 To Hanover Medical School, Satellite Center Freiburg, Freiburg, Germany.; Department of Rheumatology and Immunology, Hannover Medical School, Hannover, Germany., Pietrucha B; Department of Immunology, The Children's Memorial Health Institute, Av. Dzieci Polskich 20, 04-730, Warsaw, Poland., Plebani A; Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, Department of Clinical and Experimental Sciences, University of Brescia and ASST-Spedali Civili di Brescia, Brescia, Italy., van der Flier M; Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands., van Aerde K; Department of Pediatrics, Amalia's Children Hospital, Radboud University Medical Center, Nijmegen, the Netherlands., Kilic SS; Department of Pediatric Immunology and Rheumatology, the School of Medicine, Uludag University, Bursa, Turkey., Reda SM; Department of Pediatrics, Children's Hospital, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Kostyuchenko L; Center of Pediatric Immunology, Western Ukrainian Specialized Children's Medical Centre, Lviv, Ukraine., McDermott E; Clinical Immunology and Allergy Unit, Nottingham University Hospitals, Nottingham, UK., Galal N; Department of Pediatrics, Cairo University Specialized Pediatric Hospital, Cairo, Egypt., Pignata C; Department of Translational Medical Sciences, Section of Pediatrics, Federico II University, Naples, Italy., Pérez JLS; Infectious Diseases and Immunodeficiencies Unit, Service of Pediatrics, Hospital Universitario Virgen de Las Nieves, Granada, Spain., Laws HJ; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine University, Duesseldorf, Germany., Niehues T; Centre for Child and Adolescent Health, Helios Klinikum Krefeld, Krefeld, Germany., Kutukculer N; Faculty of Medicine, Department of Pediatric Immunology, Ege University, Izmir, Turkey., Seidel MG; Research Unit for Pediatric Hematology and Immunology, Division of Pediatric Hemato-Oncology, Department of Pediatrics and Adolescent Medicine, Medical University Graz, Graz, Austria., Marques L; Pediatric Department, Infectious Diseases and Immunodeficiencies Unit, Porto Hospital Center, Porto, Portugal., Ciznar P; Pediatric Department, Faculty of Medicine, Children University Hospital in Bratislava, Comenius University in Bratislava, Bratislava, Slovakia., Edgar JDM; The Royal Hospitals & Queen's University, Belfast, UK., Soler-Palacín P; Pediatric Infectious Diseases and Immunodeficiencies Unit, Vall D'Hebron Research Institute, Hospital Universitari Vall D'Hebron, Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain., von Bernuth H; Department of Pediatric Pneumology, Immunology and Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Department of Immunology, Labor Berlin Charité - Vivantes GmbH, Berlin, Germany.; Berlin Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, Berlin, Germany., Krueger R; Department of Pediatric Pneumology, Immunology and Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany., Meyts I; Department of Pediatrics, University Hospitals Leuven, and the Laboratory for Inborn Errors of Immunity, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium., Baumann U; Department of Paediatric Pulmonology, Allergy and Neonatology, Hannover Medical School, Hannover, Germany., Kanariou M; Department of Immunology and Histocompatibility, Centre for Primary Immunodeficiencies, 'Aghia Sophia' Children's Hospital, Athens, Greece., Grimbacher B; Institute for Immunodeficiency, Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; RESIST - Cluster of Excellence 2155 To Hanover Medical School, Satellite Center Freiburg, Freiburg, Germany.; DZIF-German Center for Infection Research, Satellite Center Freiburg, Freiburg, Germany; Centre for Integrative Biological Signalling Studies, Albert-Ludwigs University, Freiburg, Germany., Hauck F; Department of Pediatrics, Dr. Von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany., Graf D; MVZ Dr. Reising-Ackermann Und Kollegen, Leipzig, Germany., Granado LIG; Primary Immunodeficiencies Unit, Pediatrics, Hospital 12 Octubre, Complutense University School of Medicine, Madrid, Spain., Prader S; Division of Immunology and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland., Reisli I; Department of Pediatrics, Division of Pediatric Immunology and Allergy, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey., Slatter M; Primary Immunodeficiency Group, Paediatric Immunology and Haematopoietic Stem Cell Transplantation, Translational and Clinical Research Institute, Great North Childrens' Hospital, Newcastle University, Newcastle upon Tyne, UK., Rodríguez-Gallego C; Department of Immunology, Dr. Negrin University Hospital of Gran Canaria, University Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain., Arkwright PD; Lydia Becker Institute of Immunology and Inflammation, University of Manchester and Royal Manchester Children's Hospital, Manchester, UK., Bethune C; University Hospital Plymouth NHS Trust, Plymouth, UK., Deripapa E; National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia., Sharapova SO; Research Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk region, Minsk, Belarus., Lehmberg K; Division for Pediatric Stem Cell Transplantation and Immunology, Clinic for Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Davies EG; Great Ormond Street Hospital and UCL Great Ormond Street Institute of Child Health, London, UK., Schuetz C; Department of Pediatrics, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Kindle G; Institute for Immunodeficiency, Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; FREEZE Biobank, Center for Biobanking, Medical Center and Faculty of Medicine, University of Freiburg, Breisacher Str. 115, 79106, Freiburg, Germany., Schubert R; Division of Allergology, Pulmonology and Cystic Fibrosis, Department for Children and Adolescents, Goethe University, Frankfurt, Germany.

Publikováno v: Journal of clinical immunology [J Clin Immunol] 2021 Nov; Vol. 41 (8), pp. 1878-1892. Date of Electronic Publication: 2021 Sep 03.