Zobrazeno 1 - 7
of 7
pro vyhledávání: '"RP, regulatory particle"'
Autor:
Juliana Bragazzi Cunha, Jordan A. Shavit, Herbert L. Bonkovsky, Dhiman Maitra, Jared S. Elenbaas, M. Bishr Omary
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 4, Pp 535-548 (2019)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Genetic porphyrias comprise eight diseases caused by defects in the heme biosynthetic pathway that lead to accumulation of heme precursors. Consequences of porphyria include photosensitivity, liver damage and increased risk of hepatocellular carcinom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0af3ebb574e4ee6cf3f3b54e0ba117c
https://doi.org/10.1016/j.jcmgh.2019.06.006
https://doi.org/10.1016/j.jcmgh.2019.06.006
Publikováno v:
The Journal of Biological Chemistry
The proteasome is a large protease complex that degrades many different cellular proteins. In eukaryotes, the 26S proteasome contains six different subunits of the ATPases associated with diverse cellular activities family, Rpt1–Rpt6, which form a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613d312374996d43ddc183de820a3ad0
http://europepmc.org/articles/PMC8134078
http://europepmc.org/articles/PMC8134078
Publikováno v:
The Journal of Biological Chemistry
Changing physiological conditions can increase the need for protein degradative capacity in eukaryotic cells. Both the ubiquitin-proteasome system and autophagy contribute to protein degradation. However, these processes can be differently regulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91cf769d42b57519d86297cd9d2eeafb
https://doi.org/10.1016/j.jbc.2021.101494
https://doi.org/10.1016/j.jbc.2021.101494
Publikováno v:
The Journal of Biological Chemistry
The ubiquitin (Ub)-proteasome system is the primary mechanism for maintaining protein homeostasis in eukaryotes, yet the underlying signaling events and specificities of its components are poorly understood. Proteins destined for degradation are tagg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4c60b13a61d842e3397a7c43c4d339
https://doi.org/10.1016/j.jbc.2021.101052
https://doi.org/10.1016/j.jbc.2021.101052
Publikováno v:
The Journal of Biological Chemistry
The proteasome selectively degrades proteins. It consists of a core particle (CP), which contains proteolytic active sites that can associate with different regulators to form various complexes. How these different complexes are regulated and affecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586c1f16e192297ca41c552e98e8f86a
https://doi.org/10.1016/j.jbc.2021.100468
https://doi.org/10.1016/j.jbc.2021.100468
Autor:
Haojie Lu, Yana Ma, Fuqiang Yuan, Qilin Ma, Tao Tao, Pengyuan Yang, Yinhua Yu, Wenbo Lin, Xiaomin Wang, Jie Jiang, Pan You
Publikováno v:
Bioscience Reports
p27Kip1 is a key cell-cycle regulator whose level is primarily regulated by the ubiquitin–proteasome degradation pathway. Its β1 subunit is one of seven β subunits that form the β-ring of the 20S proteasome, which is responsible for degradation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083062fa4699d5b4e52cd28dfe234fb9
https://doi.org/10.1042/bsr20130013
https://doi.org/10.1042/bsr20130013
Autor:
Paola Pietroni, David M. Roberts, Rasmus Hartmann-Petersen, Jonathan Cook, Nishi Vasisht, Robert A. Spooner, Lynne M. Roberts, J. Michael Lord
Publikováno v:
Biochemical Journal
The plant cytotoxin ricin enters mammalian cells by receptor-mediated endocytosis, undergoing retrograde transport to the ER (endoplasmic reticulum) where its catalytic A chain (RTA) is reductively separated from the holotoxin to enter the cytosol an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48fbc80942f1b6de98004cc1014b8f84
http://wrap.warwick.ac.uk/54947/1/WRAP_Pietroni_4530435.pdf
http://wrap.warwick.ac.uk/54947/1/WRAP_Pietroni_4530435.pdf
