Virtual Screening of Potential RoxS Inhibitors and Evaluation of Their Antimicrobial Activity in Combination with Antibiotics against Clinically Resistant Bacteria

Autor: Ya-Yan Huang, Jia-Hao Li, Ting-Ting Liang, Ze-An Zhao, Jun Xu, Wen-Ying Chen

Publikováno v: Antibiotics, Vol 12, Iss 9, p 1422 (2023)

Pseudomonas aeruginosa with difficult-to-treat resistance has been designated as an urgent or serious threat by the CDC in the United States; therefore, novel antibacterial drugs and combination strategies are urgently needed. The sensor kinase RoxS

Externí odkaz: https://doaj.org/article/76bf25aea8714de285349a6fa03e4767

sRNA-mediated activation of gene expression by inhibition of 5'-3’ exonucleolytic mRNA degradation

Autor: Sylvain Durand, Frédérique Braun, Anne-Catherine Helfer, Pascale Romby, Ciarán Condon

Publikováno v: eLife, Vol 6 (2017)

Post-transcriptional control by small regulatory RNA (sRNA) is critical for rapid adaptive processes. sRNAs can directly modulate mRNA degradation in Proteobacteria without interfering with translation. However, Firmicutes have a fundamentally differ

Externí odkaz: https://doaj.org/article/9d7514fd183a4110ac30ecc87d0692c2

Optimization of Cyanine Dye Stability and Analysis of FRET Interaction on DNA Microarrays

Autor: Marcel von der Haar, Christopher Heuer, Martin Pähler, Kathrin von der Haar, Patrick Lindner, Thomas Scheper, Frank Stahl

Publikováno v: Biology, Vol 5, Iss 4, p 47 (2016)

The application of DNA microarrays for high throughput analysis of genetic regulation is often limited by the fluorophores used as markers. The implementation of multi-scan techniques is limited by the fluorophores’ susceptibility to photobleaching

Externí odkaz: https://doaj.org/article/4bacf6c4497843599fe16f9bb3f27e45

Optimization of cyanine dye stability and analysis of FRET interaction on DNA microarrays

Autor: Thomas Scheper, Martin Pahler, Patrick Lindner, Kathrin von der Haar, Frank Stahl, Marcel von der Haar, Christopher Heuer

Publikováno v: BASE-Bielefeld Academic Search Engine
Biology 5 (2016), Nr. 4
Biology
Biology; Volume 5; Issue 4; Pages: 47
Biology, Vol 5, Iss 4, p 47 (2016)

The application of DNA microarrays for high throughput analysis of genetic regulation is often limited by the fluorophores used as markers. The implementation of multi-scan techniques is limited by the fluorophores’ susceptibility to photobleaching

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a74940e312baf180da920de59d4f393

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