Phase I Clinical Trial on Pleural Mesothelioma Using Neoadjuvant Local Administration of Paclitaxel-Loaded Mesenchymal Stromal Cells (PACLIMES Trial): Study Rationale and Design.

Autor: Stella GM; Department of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.; Unit of Respiratory Diseases, Cardiothoracic and Vascular Department, IRCCS Policlinico San Matteo, 27100 Pavia, Italy., Lisini D; Cell Therapy Production Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy., Pedrazzoli P; Department of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.; Medical Oncology Unit, Oncology and Hematology Department, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy., Galli G; Department of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.; Medical Oncology Unit, Oncology and Hematology Department, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy., Bortolotto C; Diagnostic Imaging Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.; Radiology Unit-Diagnostic Imaging I, Department of Diagnostic Medicine, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy., Melloni G; Unit of Thoracic Surgery, Cardiothoracic and Vascular Department, IRCCS Policlinico San Matteo, 27100 Pavia, Italy., D'Ambrosio G; Pathology Unit, Department of Diagnostical Services and Imaging, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy., Klersy C; Biostatistics and Clinical Trial Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, 27100 Pavia, Italy., Grosso A; Unit of Respiratory Diseases, Cardiothoracic and Vascular Department, IRCCS Policlinico San Matteo, 27100 Pavia, Italy., Paino F; CRC StaMeTec, Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy., Tomaselli S; Unit of Respiratory Diseases, Cardiothoracic and Vascular Department, IRCCS Policlinico San Matteo, 27100 Pavia, Italy., Saracino L; Unit of Respiratory Diseases, Cardiothoracic and Vascular Department, IRCCS Policlinico San Matteo, 27100 Pavia, Italy., Alessandri G; CRC StaMeTec, Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy., Pessina A; CRC StaMeTec, Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy., Grignani E; Environmental Research Center, Istituti Clinici Scientifici Maugeri IRCCS, 27100 Pavia, Italy., Rosti V; Phase 1 Clinical Trial Unit and Experimental Therapy, IRCCS Policlinico San Matteo, 27100 Pavia, Italy., Corsico AG; Department of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.; Unit of Respiratory Diseases, Cardiothoracic and Vascular Department, IRCCS Policlinico San Matteo, 27100 Pavia, Italy., Comoli P; Cell Factory, Pediatric Hematology/Oncology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy., Agustoni F; Department of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.; Medical Oncology Unit, Oncology and Hematology Department, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.

Publikováno v: Cancers [Cancers (Basel)] 2024 Oct 04; Vol. 16 (19). Date of Electronic Publication: 2024 Oct 04.

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Biochemical properties of chromatin domains define genome compartmentalization.

Autor: Lucini F; INGM, Istituto Nazionale di Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan 20122, Italy., Petrini C; IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan 20139, Italy., Salviato E; IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan 20139, Italy., Pal K; IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan 20139, Italy., Rosti V; INGM, Istituto Nazionale di Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan 20122, Italy.; ITB-CNR, Institute of Biomedical Technologies, National Research Council, Segrate 20054, Italy., Gorini F; INGM, Istituto Nazionale di Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan 20122, Italy., Santarelli P; INGM, Istituto Nazionale di Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan 20122, Italy., Quadri R; INGM, Istituto Nazionale di Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan 20122, Italy., Lembo G; IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan 20139, Italy., Graziano G; IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan 20139, Italy., Di Patrizio Soldateschi E; INGM, Istituto Nazionale di Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan 20122, Italy.; ITB-CNR, Institute of Biomedical Technologies, National Research Council, Segrate 20054, Italy., Tagliaferri I; IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan 20139, Italy., Pinatel E; ITB-CNR, Institute of Biomedical Technologies, National Research Council, Segrate 20054, Italy., Sebestyén E; IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan 20139, Italy., Rotta L; IEO, European Institute of Oncology IRCCS, Milan 20141, Italy., Gentile F; Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Milan 20122, Italy., Vaira V; Division of Pathology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Lanzuolo C; INGM, Istituto Nazionale di Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan 20122, Italy.; ITB-CNR, Institute of Biomedical Technologies, National Research Council, Segrate 20054, Italy., Ferrari F; IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan 20139, Italy.; IGM-CNR, Institute of Molecular Genetics 'Luigi Luca Cavalli-Sforza', National Research Council, Pavia 27100, Italy.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Jul 08; Vol. 52 (12), pp. e54.

Natural history of Ras‐associated autoimmune leukoproliferative disorder: A 20‐year follow‐up of a NRAS‐mutated patient excluding a malignant progression.

Autor: Rivalta, B., Attardi, E., Cifaldi, C., Rosti, V., Pacillo, L., Hajrullaj, H., Di Cesare, S., Amodio, D., Algeri, M., Luciani, M., Barzaghi, F., Finocchi, A., Di Matteo, G., Aiuti, A., Locatelli, F., Voso, M. T., Palumbo, G., Cancrini, C.

Publikováno v: British Journal of Haematology; Jan2024, Vol. 204 Issue 1, pe6-e10, 5p

Type 1 CALR mutation allele frequency correlates with CD34/CXCR4 expression in myelofibrosis-type megakaryocyte dysplasia: A mechanism of disease progression?

Autor: Barosi G; Center for the Study of Myelofibrosis, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S. Matteo Foundation, Pavia, Italy. barosig@smatteo.pv.it., Campanelli R; Center for the Study of Myelofibrosis, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S. Matteo Foundation, Pavia, Italy., Catarsi P; Center for the Study of Myelofibrosis, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S. Matteo Foundation, Pavia, Italy., Abbà C; General Medicine 2, Center for Sistemic Amyloidosis and High Complexity Diseases, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo Foundation, Pavia, Italy., Carolei A; Center for the Study of Myelofibrosis, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S. Matteo Foundation, Pavia, Italy., Massa M; General Medicine 2, Center for Sistemic Amyloidosis and High Complexity Diseases, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo Foundation, Pavia, Italy., Gale RP; Centre for Haematology Research, Imperial College London, London, UK., Rosti V; Center for the Study of Myelofibrosis, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S. Matteo Foundation, Pavia, Italy.

Publikováno v: Blood cancer journal [Blood Cancer J] 2024 Jan 23; Vol. 14 (1), pp. 18. Date of Electronic Publication: 2024 Jan 23.