Zobrazeno 1 - 10
of 557
pro vyhledávání: '"ROSCOE O. BRADY"'
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Individuals with schizophrenia are 10 times more likely to have a tobacco use disorder than the general population. Up to 80% of those with schizophrenia smoke tobacco regularly, a prevalence three-times that of the general population. Despite the st
Externí odkaz:
https://doaj.org/article/585dfb6eeaa64750bcadab60a5e0d249
Autor:
Heather Burrell Ward, Adam Beermann, Uzma Nawaz, Mark A. Halko, Amy C. Janes, Lauren V. Moran, Roscoe O. Brady
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Tobacco use is the top preventable cause of early mortality in schizophrenia. Over 60% of people with schizophrenia smoke, three times the general prevalence. The biological basis of this increased risk is not understood, and existing interventions d
Externí odkaz:
https://doaj.org/article/a926e4e0ff5843d5be366433d7d9ae7b
Publikováno v:
Biomarkers in Neuropsychiatry, Vol 4, Iss , Pp 100032- (2021)
Instead of matching neuroimaging to static clinical targets, it is currently possible to use dynamic biobehavioral markers of cognition, functioning, behavior, and symptoms captured through a person’s smartphone. This paper reviews the published li
Externí odkaz:
https://doaj.org/article/2b7cbfb00d4d4c4991b83a28b9020d77
Autor:
Melissa Hwang, Youkyung S. Roh, Jessica Talero, Bruce M. Cohen, Justin T. Baker, Roscoe O. Brady, Dost Öngür, Ann K. Shinn
Publikováno v:
NeuroImage: Clinical, Vol 32, Iss , Pp 102893- (2021)
Background: Auditory hallucinations (AH) are typically associated with schizophrenia (SZ), but they are also prevalent in bipolar disorder (BD). Despite the large body of research on the neural correlates of AH in SZ, the pathophysiology underlying A
Externí odkaz:
https://doaj.org/article/8c4ddf8bb402439c9a4922ec0b1caedb
Autor:
Roscoe O. Brady, Adam Beermann, Madelaine Nye, Shaun M. Eack, Raquelle Mesholam-Gately, Matcheri S. Keshavan, Kathryn E. Lewandowski
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Background: Psychotic disorders are characterized by impairment in social cognitive processing, which is associated with poorer community functioning. However, the neural mechanisms of social impairment in psychosis remain unclear. Social impairment
Externí odkaz:
https://doaj.org/article/a3e9435734484b91a97e5cfd11b7370d
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 9, Pp 2808-2817 (2010)
Fabry disease is an X-linked disorder caused by mutations in the GLA gene encoding for α-galactosidase A (AGA, EC 3.2.1.22). Measurement of AGA enzyme activity using cell homogenates can easily identify men with Fabry disease, but in women, the degr
Externí odkaz:
https://doaj.org/article/140f540b3f1c4633aedda7fa464f405a
Autor:
Maja Di Rocco, Fiorina Giona, Francesca Carubbi, Silvia Linari, Fabrizio Minichilli, Roscoe O. Brady, Giuliano Mariani, Maria Domenica Cappellini
Publikováno v:
Haematologica, Vol 93, Iss 8 (2008)
Background Gaucher disease is the first lysosomal storage disease for which specific therapy became available. Over 4800 patients have been treated with enzyme replacement therapy. Analysis of Gaucher disease registry data has outlined the clinical h
Externí odkaz:
https://doaj.org/article/25bf3da6495447008c58b770cd19c5e0
Publikováno v:
Journal of Lipid Research, Vol 4, Iss 2, Pp 144-150 (1963)
Tetrolyl-CoA and propiolyl-CoA have been shown to be strong noncompetitive inhibitors of fatty acid synthesis. Acrylyl-CoA and isocrotonyl-CoA also inhibit, but much higher concentrations are required. It is suggested that this inhibition occurs thro
Externí odkaz:
https://doaj.org/article/2982e2e61f974778be38d70fa4210338
Publikováno v:
Journal of Lipid Research, Vol 3, Iss 2, Pp 243-245 (1962)
An enzyme preparation obtained from brain tissue catalyzes the stereospecific reduction of crotonyl CoA to butyrate. Tritium from TPNH3 was localized predominantly on the β-carbon of recovered butyric acid. Both this enzyme and a preparation from ad
Externí odkaz:
https://doaj.org/article/53658d5c22ac451586da2494867328d9
Autor:
Amy Farabaugh, Albert Yeung, George I. Papakostas, Nhi-Ha Trinh, Laura E. Dichtel, Cristina Cusin, Christina Dording, Benjamin G. Shapero, Emily Hahn, Trina E. Chang, Maren Nyer, Justin A. Chen, Elizabeth M Rao, Linda L. Carpenter, David A. Schoenfeld, Roscoe O. Brady, Paolo Cassano, Audrey R. Tyrka, Karen K. Miller, Lawrence H. Price, Darin D. Dougherty, Allison Kimball, Lauren B. Fisher, Thilo Deckersbach, Ravinder J. Singh, Maurizio Fava, Paola Pedrelli, David Mischoulon
Publikováno v:
American Journal of Psychiatry. 177:965-973
Low-dose testosterone has been shown to improve depression symptom severity, fatigue, and sexual function in small studies in women not formally diagnosed with major depressive disorder. The authors sought to determine whether adjunctive low-dose tra