Zobrazeno 1 - 10
of 159
pro vyhledávání: '"ROP18"'
Autor:
Emi Hashizaki, Miwa Sasai, Daisuke Okuzaki, Tsubasa Nishi, Takashi Kobayashi, Shiroh Iwanaga, Masahiro Yamamoto
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Toxoplasma gondii secretes various virulence effector molecules into host cells to disrupt host interferon-γ (IFN-γ)-dependent immunity. Among these effectors, ROP18 directly phosphorylates and inactivates IFN-inducible GTPases, such as im
Externí odkaz:
https://doaj.org/article/8cce4e57ccc947a185c4c4f86535081e
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-14 (2020)
Abstract Background Toxoplasma gondii is an opportunistic protozoan infecting almost one-third of the world’s population. Toxoplasma gondii rhoptry protein 18 (TgROP18) is a key virulence factor determining the parasite’s acute virulence and is s
Externí odkaz:
https://doaj.org/article/e6ad8307f829401eada65dfd887f6bb7
Autor:
Keon-Woong Yoon, Ki-Back Chu, Hae-Ji Kang, Min-Ju Kim, Gi-Deok Eom, Jie Mao, Su-Hwa Lee, Md Atique Ahmed, Fu-Shi Quan
Publikováno v:
Vaccines, Vol 10, Iss 10, p 1588 (2022)
Heterologous immunization is garnering attention as a promising strategy to improve vaccine efficacy. Vaccines based on recombinant baculovirus (rBV) and virus-like particle (VLP) are safe for use, but heterologous immunization studies incorporating
Externí odkaz:
https://doaj.org/article/68ebe5c330b3471a9e9a13c35a47a7c9
Autor:
Li-Juan Zhou, Min Chen, Santhosh Puthiyakunnon, Cheng He, Jing Xia, Cynthia Y. He, Sheng-Qun Deng, Hong-Juan Peng
Publikováno v:
Parasites & Vectors, Vol 12, Iss 1, Pp 1-18 (2019)
Abstract Background Apoptosis plays a critical role in the embryonic development, homeostasis of immune system and host defense against intracellular microbial pathogens. Infection by the obligate intracellular pathogen Toxoplasma gondii can both inh
Externí odkaz:
https://doaj.org/article/cae4ce966b2d4f4182c901533eb73da2
Autor:
Kun Yin, Guihua Zhao, Chao Xu, Xiao Qiu, Biwei Wen, Hui Sun, Gongzhen Liu, Ye Liu, Qingsong Zhao, Qingkuan Wei, Bingcheng Huang, Ge Yan, Jianping Cao
Publikováno v:
Parasites & Vectors, Vol 12, Iss 1, Pp 1-14 (2019)
Abstract Background Rhoptry protein 18 (ROP18) is a key virulence factor of Toxoplasma gondii. The host’s immune responses mediated by immune-related GTPases (IRGs) could be blocked by ROP18’s kinase activity. ROP18 also interacts with various su
Externí odkaz:
https://doaj.org/article/8d1bd566d1ef45ee8751996b23711dac
Autor:
An, Ran, Tang, Yuewen, Chen, Lijian, Cai, Haijian, Lai, De-Hua, Liu, Kang, Wan, Lijuan, Gong, Linli, Yu, Li, Luo, Qingli, Shen, Jilong, Lun, Zhao-Rong, Ayala, Francisco J., Du, Jian
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Jun 01. 115(23), E5344-E5352.
Externí odkaz:
https://www.jstor.org/stable/26510341
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Toxoplasma gondii secretes a number of virulence-related effector proteins, such as the rhoptry protein 18 (ROP18). To further broaden our understanding of the molecular functions of ROP18, we examined the transcriptional response of human embryonic
Externí odkaz:
https://doaj.org/article/8b0b04427866427f9273ceb76d150e24
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Diana Alejandra Cortés, María Camila Aguilar, Hernán Andres Ríos, Francisco José Rodríguez, Kelly Verónica Montes, Jorge Enrique Gómez- Marín, Alejandra de-la-Torre
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 18, Iss , Pp - (2020)
Propose: To report two cases of severe acute multi-systemic failure with bilateral ocular toxoplasmosis in immunocompetent patients from urban settings in Colombia. Observations: We report two immunocompetent male patients aged 44- and 67-years-old w
Externí odkaz:
https://doaj.org/article/3d0a59345b914ed5b60a046475e5119e
Autor:
Alejandro Hernández-de-los-Ríos, Mateo Murillo-Leon, Luz Eliana Mantilla-Muriel, Ailan Farid Arenas, Mónica Vargas-Montes, Néstor Cardona, Alejandra de-la-Torre, Juan Carlos Sepúlveda-Arias, Jorge Enrique Gómez-Marín
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Toxoplasma gondii ROP16 and ROP18 proteins have been identified as important virulence factors for this parasite. Here, we describe the effect of ROP16 and ROP18 proteins on peripheral blood mononuclear cells (PBMCs) from individuals with different c
Externí odkaz:
https://doaj.org/article/cf10e0e1cda74e60ba333a6ba6bcaacb