Zobrazeno 1 - 10
of 403
pro vyhledávání: '"RONAN ROUSSEL"'
Autor:
Sarah Meulebrouck, Judith Merrheim, Gurvan Queniat, Cyril Bourouh, Mehdi Derhourhi, Mathilde Boissel, Xiaoyan Yi, Alaa Badreddine, Raphaël Boutry, Audrey Leloire, Bénédicte Toussaint, Souhila Amanzougarene, Emmanuel Vaillant, Emmanuelle Durand, Hélène Loiselle, Marlène Huyvaert, Aurélie Dechaume, Victoria Scherrer, Piero Marchetti, Beverley Balkau, Guillaume Charpentier, Sylvia Franc, Michel Marre, Ronan Roussel, Raphaël Scharfmann, Miriam Cnop, Mickaël Canouil, Morgane Baron, Philippe Froguel, Amélie Bonnefond
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Functional genetics has identified drug targets for metabolic disorders. Opioid use impacts metabolic homeostasis, although mechanisms remain elusive. Here, we explore the OPRD1 gene (encoding delta opioid receptor, DOP) to understand its im
Externí odkaz:
https://doaj.org/article/78b374b3ff9b43728d9fb6ee8aab174e
Autor:
Iulia Petria, Samuel Albuquerque, Gaël Varoquaux, Jill-Jênn Vie, Nicolas Venteclef, Kamel Mohammedi, Ronan Roussel, Marion Camoin, Gianluca Perseghin, Gilberto Velho, Louis Potier
Publikováno v:
Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-8 (2022)
Abstract Background Cardiovascular risk and body-weight management are both emerging challenges of type 1 diabetes care. We evaluated the association between intraindividual variability of body-weight and risk of cardiovascular events in people with
Externí odkaz:
https://doaj.org/article/88ee4c63f0ea4a568823f7151378b58d
Autor:
Manuel Sanchez, Caroline Kannengiesser, Sophie Hoang, Louis Potier, Frédéric Fumeron, Nicolas Venteclef, André Scheen, Jean-François Gautier, Samy Hadjadj, Michel Marre, Ronan Roussel, Kamel Mohammedi, Gilberto Velho
Publikováno v:
Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-10 (2022)
Abstract Background Type 1 diabetes is associated with accelerated vascular aging and advanced atherosclerosis resulting in increased rates of cardiovascular disease and premature death. We evaluated associations between Leukocyte telomere length (LT
Externí odkaz:
https://doaj.org/article/1f8da084f67f431cb678c0931f3188f9
Autor:
Marion Camoin, Gilberto Velho, Pierre-Jean Saulnier, Louis Potier, Yawa Abouleka, Charlyne Carpentier, Severine Dubois, Alice Larroumet, Vincent Rigalleau, Elise Gand, Olivier Bourron, Lyse Bordier, André Scheen, Samy Hadjadj, Ronan Roussel, Michel Marre, Kamel Mohammedi
Publikováno v:
Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-10 (2022)
Abstract Background Cardiovascular disease (CVD) and nontraumatic lower-limb amputation (LLA) each results in reduced life expectancy in patients with type 1 diabetes, but the differential burden between these conditions is unknown. We compared the e
Externí odkaz:
https://doaj.org/article/d6f13f70e4d54db38bcbda099fa4d735
Autor:
Adrien Joseph, Hui Chen, Gerasimos Anagnostopoulos, Léa Montégut, Antoine Lafarge, Omar Motiño, Maria Castedo, Maria Chiara Maiuri, Karine Clément, Safae Terrisse, Anne Laure Martin, Ines Vaz-Luis, Fabrice Andre, Franziska Grundler, Françoise Wilhelmi de Toledo, Frank Madeo, Laurence Zitvogel, François Goldwasser, Benoit Blanchet, Frédéric Fumeron, Ronan Roussel, Isabelle Martins, Guido Kroemer
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-14 (2021)
Abstract In mice, the plasma concentrations of the appetite-stimulatory and autophagy-inhibitory factor acyl-coenzyme A binding protein (ACBP, also called diazepam-binding inhibitor, DBI) acutely increase in response to starvation, but also do so upo
Externí odkaz:
https://doaj.org/article/87eab42d99e743b7ae47f07c8dddc3bc
Autor:
Fawaz Alzaid, Jean‐Baptiste Julla, Marc Diedisheim, Charline Potier, Louis Potier, Gilberto Velho, Bénédicte Gaborit, Philippe Manivet, Stéphane Germain, Tiphaine Vidal‐Trecan, Ronan Roussel, Jean‐Pierre Riveline, Elise Dalmas, Nicolas Venteclef, Jean‐François Gautier
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 10, Pp 1-12 (2020)
Abstract Early in the COVID‐19 pandemic, type 2 diabetes (T2D) was marked as a risk factor for severe disease and mortality. Inflammation is central to the aetiology of both conditions where variations in immune responses can mitigate or aggravate
Externí odkaz:
https://doaj.org/article/7c72d6f547d64ae5b2a37caae2a48163
Publikováno v:
Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-3 (2021)
Abstract In a recent meta-analysis of randomized controlled trials of sodium glucose co-transporter 2 inhibitors (SGLT2i) in patients with diabetes, Lin and colleagues showed a positive association between SGLT2i-induced blood pressure and weight red
Externí odkaz:
https://doaj.org/article/3e86893b93414487b33e28b85d2229da
Autor:
Marie Mortreux, Ewout Foppen, Raphaël G. Denis, Mireia Montaner, Nadim Kassis, Jessica Denom, Mylène Vincent, Frédéric Fumeron, Margaux Kujawski-Lafourcade, Fabrizio Andréelli, Beverley Balkau, Michel Marre, Ronan Roussel, Christophe Magnan, Hirac Gurden, Stéphanie Migrenne-Li
Publikováno v:
Molecular Metabolism, Vol 29, Iss , Pp 182-196 (2019)
Objective: Prokineticin 2 (PROK2) is a hypothalamic neuropeptide that plays a critical role in the rhythmicity of physiological functions and inhibits food intake. PROK2 is also expressed in the main olfactory bulb (MOB) as an essential factor for ne
Externí odkaz:
https://doaj.org/article/0f8f9f566bed4889bbea5fd285ea8c91
Autor:
Amand F. Schmidt, Michael V. Holmes, David Preiss, Daniel I. Swerdlow, Spiros Denaxas, Ghazaleh Fatemifar, Rupert Faraway, Chris Finan, Dennis Valentine, Zammy Fairhurst-Hunter, Fernando Pires Hartwig, Bernardo Lessa Horta, Elina Hypponen, Christine Power, Max Moldovan, Erik van Iperen, Kees Hovingh, Ilja Demuth, Kristina Norman, Elisabeth Steinhagen-Thiessen, Juri Demuth, Lars Bertram, Christina M. Lill, Stefan Coassin, Johann Willeit, Stefan Kiechl, Karin Willeit, Dan Mason, John Wright, Richard Morris, Goya Wanamethee, Peter Whincup, Yoav Ben-Shlomo, Stela McLachlan, Jackie F. Price, Mika Kivimaki, Catherine Welch, Adelaida Sanchez-Galvez, Pedro Marques-Vidal, Andrew Nicolaides, Andrie G. Panayiotou, N. Charlotte Onland-Moret, Yvonne T. van der Schouw, Giuseppe Matullo, Giovanni Fiorito, Simonetta Guarrera, Carlotta Sacerdote, Nicholas J. Wareham, Claudia Langenberg, Robert A. Scott, Jian’an Luan, Martin Bobak, Sofia Malyutina, Andrzej Pająk, Ruzena Kubinova, Abdonas Tamosiunas, Hynek Pikhart, Niels Grarup, Oluf Pedersen, Torben Hansen, Allan Linneberg, Tine Jess, Jackie Cooper, Steve E. Humphries, Murray Brilliant, Terrie Kitchner, Hakon Hakonarson, David S. Carrell, Catherine A. McCarty, Kirchner H. Lester, Eric B. Larson, David R. Crosslin, Mariza de Andrade, Dan M. Roden, Joshua C. Denny, Cara Carty, Stephen Hancock, John Attia, Elizabeth Holliday, Rodney Scott, Peter Schofield, Martin O’Donnell, Salim Yusuf, Michael Chong, Guillaume Pare, Pim van der Harst, M. Abdullah Said, Ruben N. Eppinga, Niek Verweij, Harold Snieder, Lifelines Cohort authors, Tim Christen, D. O. Mook-Kanamori, the ICBP Consortium, Stefan Gustafsson, Lars Lind, Erik Ingelsson, Raha Pazoki, Oscar Franco, Albert Hofman, Andre Uitterlinden, Abbas Dehghan, Alexander Teumer, Sebastian Baumeister, Marcus Dörr, Markus M. Lerch, Uwe Völker, Henry Völzke, Joey Ward, Jill P. Pell, Tom Meade, Ingrid E. Christophersen, Anke H. Maitland-van der Zee, Ekaterina V. Baranova, Robin Young, Ian Ford, Archie Campbell, Sandosh Padmanabhan, Michiel L. Bots, Diederick E. Grobbee, Philippe Froguel, Dorothée Thuillier, Ronan Roussel, Amélie Bonnefond, Bertrand Cariou, Melissa Smart, Yanchun Bao, Meena Kumari, Anubha Mahajan, Jemma C. Hopewell, Sudha Seshadri, the METASTROKE Consortium of the ISGC, Caroline Dale, Rui Providencia E. Costa, Paul M. Ridker, Daniel I. Chasman, Alex P. Reiner, Marylyn D. Ritchie, Leslie A. Lange, Alex J. Cornish, Sara E. Dobbins, Kari Hemminki, Ben Kinnersley, Marc Sanson, Karim Labreche, Matthias Simon, Melissa Bondy, Philip Law, Helen Speedy, James Allan, Ni Li, Molly Went, Niels Weinhold, Gareth Morgan, Pieter Sonneveld, Björn Nilsson, Hartmut Goldschmidt, Amit Sud, Andreas Engert, Markus Hansson, Harry Hemingway, Folkert W. Asselbergs, Riyaz S. Patel, Brendan J. Keating, Naveed Sattar, Richard Houlston, Juan P. Casas, Aroon D. Hingorani
Publikováno v:
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background We characterised the phenotypic consequence of genetic variation at the PCSK9 locus and compared findings with recent trials of pharmacological inhibitors of PCSK9. Methods Published and individual participant level data (300,000+
Externí odkaz:
https://doaj.org/article/6496ec7ef17e440a938a2e70da19e20c
Autor:
Marc Diedisheim, Elena Carcarino, Claire Vandiedonck, Ronan Roussel, Jean-François Gautier, Nicolas Venteclef
Publikováno v:
Molecular Metabolism, Vol 41, Iss , Pp 101041- (2020)
Background: Diabetes is one of the greatest public health challenges worldwide, and we still lack complementary approaches to significantly enhance the efficacy of preventive and therapeutic approaches. Genetic and environmental factors are the culpr
Externí odkaz:
https://doaj.org/article/00a1b5a4fd344b18ae1d926d938ab7d6