Zobrazeno 1 - 10
of 11
pro vyhledávání: '"RONALD E. HURD"'
Autor:
Bo Chang, Bernie Fitzmaurice, Ronald E. Hurd, Patsy M. Nishina, Ye Liu, Xiaojie Ji, Jieping Wang
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Retinal detachments (RDs), a separation of the light-sensitive tissue of the retina from its supporting layers in the posterior eye, isolate retinal cells from their normal supply of nourishment and can lead to their deterioration and death.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97b5bafe53134384afadb7c51245753
http://europepmc.org/articles/PMC4794085
http://europepmc.org/articles/PMC4794085
Autor:
C. Herbert Pratt, Britt A. Johnson, Juergen K Naggert, Bo Chang, Akihiro Ikeda, Patsy M. Nishina, Sakae Ikeda, Gayle B. Collin, Lindsay S. Shopland, Dennis M. Maddox, Ronald E. Hurd, Mark P. Krebs
Publikováno v:
Investigative ophthalmologyvisual science. 56(6)
SYNE2 (formerly Nesprin 2 and NUANCE), the second reported member of a family of giant scaffolding proteins,1 is an ortholog of the Drosophila melanogaster muscle protein Msp-300.2 SYNE2 is a component of the linker of nucleoskeleton and cytoskeleton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e53133fd0a7b4d14347bb7e2fe4a8e
https://pubmed.ncbi.nlm.nih.gov/26066746
https://pubmed.ncbi.nlm.nih.gov/26066746
Autor:
Akihiro Ikeda, Kirstan A. Vessey, Ronald E. Hurd, Britt A. Johnson, Neal S. Peachey, S. Nusinowitz, Catherine W. Morgans, Bo Chang, John R. Heckenlively, Nicholas C. Brecha, Ronald G. Gregg, Maureen A. McCall, Muriel T. Davisson, Philippa R. Bayley, Arlene A. Hirano, Dennis S. Rice, Norm L. Hawes
Publikováno v:
Visual Neuroscience. 23:11-24
Glutamate release from photoreceptor terminals is controlled by voltage-dependent calcium channels (VDCCs). In humans, mutations in theCacna1fgene, encoding the α1Fsubunit of VDCCs, underlie the incomplete form of X-linked congenital stationary nigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c7cb25e75ce500d2e3418b556d5a13
https://doi.org/10.1017/s095252380623102x
https://doi.org/10.1017/s095252380623102x
Autor:
D. Howell, Steven Nusinowitz, Norm L. Hawes, Ronald E. Hurd, T H Roderick, J. Wang, John R. Heckenlively, Muriel T. Davisson, Bo Chang
Publikováno v:
Visual Neuroscience. 22:587-593
The Jackson Laboratory, having the world's largest collection of mouse mutant stocks and genetically diverse inbred strains, is an ideal place to discover genetically determined eye variations and disorders. In this paper, we list and describe mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb69fd2c14f73346b516d48d3146ca9
https://doi.org/10.1017/s0952523805225075
https://doi.org/10.1017/s0952523805225075
Autor:
Susan L. Ackerman, Chantal M. Longo-Guess, Kevin L. Seburn, Ronald E. Hurd, Jeff Klein, Roderick T. Bronson, Marlies P. Rossmann, Wayne N. Frankel
Publikováno v:
Nature. 419:367-374
Harlequin (Hq) mutant mice have progressive degeneration of terminally differentiated cerebellar and retinal neurons. We have identified the Hq mutation as a proviral insertion in the apoptosis-inducing factor (Aif) gene, causing about an 80% reducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1102f3bbfe30c8dfaf2f643418155890
https://doi.org/10.1038/nature01034
https://doi.org/10.1038/nature01034
Autor:
Patsy M. Nishina, Bo Chang, Jungyeon Won, Ronald E. Hurd, Jieping Wang, Wanda L. Hicks, Jürgen K. Naggert, Lan Ying Shi
Publikováno v:
Journal of Ophthalmology, Vol 2011 (2011)
Journal of Ophthalmology
Journal of Ophthalmology
The need for mouse models, with their well-developed genetics and similarity to human physiology and anatomy, is clear and their central role in furthering our understanding of human disease is readily apparent in the literature. Mice carrying mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ea7873e205990d0c5fb0916d60691a
https://doaj.org/article/617d422c88ef4639bad5debaedc7f95a
https://doaj.org/article/617d422c88ef4639bad5debaedc7f95a
Autor:
Norman L. Hawes, Nawajes A. Mandal, Naheed W. Khan, Ronald E. Hurd, Ronald Klein, Radha Ayyagari, Barbara E.K. Klein, Muriel L. Davisson, Laura J. Kopplin, John R. Heckenlively, Bo Chang, Richard S. Smith, Sudha K. Iyengar, Venkata R M Chavali
Publikováno v:
Human molecular genetics. 17(24)
We observed that a naturally occurring mouse strain developed age-related retinal degeneration (arrd2). These mice had normal fundi, electroretinograms (ERGs) and retinal histology at 6 months of age; vessel attenuation, RPE atrophy and pigmentary ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052d01679480363dac1ffb2dc43235a4
https://pubmed.ncbi.nlm.nih.gov/18805803
https://pubmed.ncbi.nlm.nih.gov/18805803
Autor:
Ji-Jing, Pang, Bo, Chang, Norman L, Hawes, Ronald E, Hurd, Muriel T, Davisson, Jie, Li, Syed M, Noorwez, Ritu, Malhotra, J Hugh, McDowell, Shalesh, Kaushal, William W, Hauswirth, Steven, Nusinowitz, Debra A, Thompson, John R, Heckenlively
Publikováno v:
Molecular vision. 11
To report the phenotype and characterization of a new, naturally occurring mouse model of hereditary retinal degeneration (rd12).The retinal phenotype of rd12 mice were studied using serial indirect ophthalmoscopy, fundus photography, electroretinogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b7f0197c446e3296674fbfaefc2576e
https://pubmed.ncbi.nlm.nih.gov/15765048
https://pubmed.ncbi.nlm.nih.gov/15765048
Autor:
Steven Nusinowitz, John R. Heckenlively, Bo Chang, Norman L. Hawes, Ronald E. Hurd, Muriel T. Davisson, Martin Friedlander
Publikováno v:
Retina (Philadelphia, Pa.). 23(4)
Purpose To characterize the phenotype and report a reliable genetic model of retinal angiogenesis and subretinal neovascularization in the mouse. Methods The mouse phenotype was characterized using ophthalmoscopy, fundus photography, fluorescein angi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64f88f713bbaf3771ffaf3828ff2a43
https://pubmed.ncbi.nlm.nih.gov/12972764
https://pubmed.ncbi.nlm.nih.gov/12972764
Autor:
Alberto C.S. Costa, Jonah J. Scott-McKean, Bo Chang, Cecilia Schmidt, Ronald E. Hurd, Steven Nusinowitz, Muriel T. Davisson
Publikováno v:
Investigative Opthalmology & Visual Science. 51:3300
The Ts65Dn mouse is the most complete widely available animal model of Down syndrome (DS). Quantitative information was generated about visual function in the Ts65Dn mouse by investigating their visual capabilities by means of electroretinography (ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4dee943ccbc05723d4c085929e432e
https://doi.org/10.1167/iovs.09-4465
https://doi.org/10.1167/iovs.09-4465