Zobrazeno 1 - 10
of 123
pro vyhledávání: '"ROMAN PEREZ-FERNANDEZ"'
Autor:
Maria J. Gonzalez-Rellan, Marcos F. Fondevila, Uxia Fernandez, Amaia Rodríguez, Marta Varela-Rey, Christelle Veyrat-Durebex, Samuel Seoane, Ganeko Bernardo, Fernando Lopitz-Otsoa, David Fernández-Ramos, Jon Bilbao, Cristina Iglesias, Eva Novoa, Cristina Ameneiro, Ana Senra, Daniel Beiroa, Juan Cuñarro, Maria DP Chantada-Vazquez, Maria Garcia-Vence, Susana B. Bravo, Natalia Da Silva Lima, Begoña Porteiro, Carmen Carneiro, Anxo Vidal, Sulay Tovar, Timo D. Müller, Johan Ferno, Diana Guallar, Miguel Fidalgo, Guadalupe Sabio, Stephan Herzig, Won Ho Yang, Jin Won Cho, Maria Luz Martinez-Chantar, Roman Perez-Fernandez, Miguel López, Carlos Dieguez, Jose M. Mato, Oscar Millet, Roberto Coppari, Ashwin Woodhoo, Gema Fruhbeck, Ruben Nogueiras
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
p53 regulates signalling pathways involved in metabolic homeostasis. Here the authors show that O-GlcNAcylation of p53 in the liver plays a key role in the physiological regulation of glucose homeostasis, potentially via controlling the expression of
Externí odkaz:
https://doaj.org/article/9769f87dfa1c4d5b90bfa5688f97fb4c
Autor:
Manuela Gago-Dominguez, Carmen M. Redondo, Manuel Calaza, Marcos Matabuena, Maria A. Bermudez, Roman Perez-Fernandez, María Torres-Español, Ángel Carracedo, J. Esteban Castelao
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Experimental data showed that endothelial lipase (LIPG) is a crucial player in breast cancer. However, very limited data exists on the role of LIPG on the risk of breast cancer in humans. We examined the LIPG-breast cancer association within
Externí odkaz:
https://doaj.org/article/8a818072829441788ab4a112069dbab0
Autor:
Xurxo García-Otero, Cristina Mondelo-García, Francisco González, Roman Perez-Fernandez, Leandro Avila, Jose Ramón Antúnez-López, Miguel González-Barcia, Alfredo Adan, Pablo Aguiar, Francisco J. Otero-Espinar, Maria A. Bermúdez, Anxo Fernández-Ferreiro
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1737 (2021)
Background: Uveitis is an infrequent disease which constitutes a major cause of ocular morbidity. Correct management is essential, being corticosteroids its cornerstone. In case of contraindication to corticosteroids or treatment failure, the use of
Externí odkaz:
https://doaj.org/article/c1cdfd300ece4df6b05e6b8da159b144
Autor:
Juan Sendon-Lago, Lorena Garcia-del Rio, Noemi Eiro, Patricia Diaz-Rodriguez, Leandro Avila, Luis O. Gonzalez, Francisco J. Vizoso, Roman Perez-Fernandez, Mariana Landin
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1127 (2021)
Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is increasingly prevalent and current therapies are not completely effective. Mesenchymal stem cells are emerging as a promising therapeutic option. Here,
Externí odkaz:
https://doaj.org/article/b6300ef3bec74cb687fc87830552521a
Autor:
Marcos Fondevila, Eva María Novoa, Maria Jesús Gonzalez-Rellan, Uxia Fernandez, Violeta Heras, Begoña Porteiro, Tamara Parracho, Marta Varela-Rey, Valentina Dorta, Natalia da Silva, Samuel Seoane, Maria Garcia-Vence, Maria Chantada-Vazquez, Susana Bravo, Ana Senra, Magdalena Leiva, Miguel Marcos, Guadalupe Sabio, Roman Perez-Fernandez, Carlos Dieguez, Vincent Prevot, Markus Schwaninger, Maria Martinez-Chantar, Robert Schwabe, Francisco Cubero, Javier Crespo, Paula Iruzubieta, Ruben Nogueiras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e878bb0a5346851d8f561211e1a50f15
https://doi.org/10.2139/ssrn.4362562
https://doi.org/10.2139/ssrn.4362562
Autor:
Juan Sendon-Lago, Samuel Seoane, Noemi Eiro, Maria A. Bermudez, Manuel Macia, Tomas Garcia-Caballero, Francisco J. Vizoso, Roman Perez-Fernandez
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-3 (2017)
Externí odkaz:
https://doaj.org/article/730e1a900a66434ab234a2474c0ebfc5
Autor:
JUAN SENDON-LAGO, SAMUEL SEOANE, FATIMA SALEH, LUCIA GARCIA-CABALLERO, MARIA E. ARIAS, NOEMI EIRO, MANUEL MACIA, FRANCISCO J. VIZOSO, ROMAN PEREZ-FERNANDEZ, JOSE SCHNEIDER
Publikováno v:
Cancer Genomics Proteomics
Background/Aim: Ovarian cancer is the most lethal of all gynecological cancers, despite advances in surgical techniques and medical treatments. During the last years, therapies based on mesenchymal stem cells and particularly their secretome (conditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ac11d142a6f4da7aabb0a477d45989
https://europepmc.org/articles/PMC9353723/
https://europepmc.org/articles/PMC9353723/
Autor:
Noemí Gómez-Lado, Manuel Macia, Efigenia Arias, Anxo Martinez-Ordoñez, Noemi Eiro, Tomás García-Caballero, Fabio Pereira, Samuel Seoane, Pablo Aguiar, Leandro Avila, Roman Perez-Fernandez, Francisco J. Vizoso
Publikováno v:
Oncogene
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Metabolic reprogramming is considered hallmarks of cancer. Aerobic glycolysis in tumors cells has been well-known for almost a century, but specific factors that regulate lactate generation and the effects of lactate in both cancer cells and stroma a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a358d1462b424fffacaaaf3dad9744f0
https://doi.org/10.1038/s41388-021-01740-6
https://doi.org/10.1038/s41388-021-01740-6
Autor:
Noemi Eiro, Juan Sendon-Lago, Sandra Cid, Jorge Saa, Nagore de Pablo, Belen Vega, Maria A. Bermudez, Roman Perez-Fernandez, Francisco J. Vizoso
Publikováno v:
Ophthalmic research. 65(5)
Introduction: Retinal homeostasis is essential to avoid retinal pigment epithelium (RPE) damage resulting in photoreceptor death and blindness. Mesenchymal stem cells-based cell therapy could contribute to the maintenance of the retinal homeostasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077f5e15782b2e8a486b7e679e21fa47
https://pubmed.ncbi.nlm.nih.gov/35584686
https://pubmed.ncbi.nlm.nih.gov/35584686
p53 regulates several signaling pathways to maintain the metabolic homeostasis of cells and modulates the cellular response to stress. Deficiency or excess of nutrients causes cellular metabolic stress, and we hypothesized that p53 could be linked to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cfc79c9066505cd025abb9f7064a5f7