Zobrazeno 1 - 10
of 4 524
pro vyhledávání: '"ROLAND L"'
Autor:
Jason S. Wasserman, Bulat Faezov, Kishan R. Patel, Alison M. Kurimchak, Seren M. Palacio, David J. Glass, Holly Fowle, Brennan C. McEwan, Qifang Xu, Ziran Zhao, Lauren Cressey, Neil Johnson, James S. Duncan, Arminja N. Kettenbach, Roland L. Dunbrack, Xavier Graña
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The Ser/Thr protein phosphatase 2 A (PP2A) regulates the dephosphorylation of many phosphoproteins. Substrate recognition are mediated by B regulatory subunits. Here, we report the identification of a substrate conserved motif [RK]-V-x-x-[VI
Externí odkaz:
https://doaj.org/article/6e9017a5c5d34b82817862a82164f6a6
Autor:
Ariana Mihai, Sang-Yun Lee, Susan Shinton, Mitchell I. Parker, Alejandra V. Contreras, Baojun Zhang, Michele Rhodes, Roland L. Dunbrack, Juan-Carlos Zúñiga-Pflücker, Maria Ciofani, Yuan Zhuang, David L. Wiest
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract T cell receptor (TCR) signaling regulates important developmental transitions, partly through induction of the E protein antagonist, Id3. Although normal γδ T cell development depends on Id3, Id3 deficiency produces different phenotypes in
Externí odkaz:
https://doaj.org/article/f10d24a302ee49119e6cd90778ad9580
Autor:
Ming-Sum Lee, Columbus Batiste, James Onwuzurike, Rachid Elkoustaf, Yi-Lin Wu, Wansu Chen, Joseph Kahwaji, Amandeep Sahota, Roland L Lee
Publikováno v:
Open Heart, Vol 11, Iss 2 (2024)
Objective Routine screening for cardiovascular disease before kidney transplantation remains controversial. This study aims to compare cardiac testing rates in patients with end-stage renal disease, referred and not referred for transplantation, and
Externí odkaz:
https://doaj.org/article/94c112ecb6eb473893bb83e88c47e7ae
Autor:
Oren Pasvolsky, Roland L. Bassett, Sassine Ghanem, Branko Cuglievan, Priti Tewari, Chitra Hosing, Samer Srour, Jeremy Ramdial, Kris M. Mahadeo, Sajad Khazal, Demetrios Petropoulos, Uday Popat, Muzaffar Qazilbash, Partow Kebriaei, Richard Champlin, Elizabeth J. Shpall, Yago Nieto
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background There is paucity of data regarding outcomes of children, adolescents and young adults (CAYA) patients with non-Hodgkin lymphoma (NHL) undergoing autologous stem cell transplantation (ASCT). Methods Patients aged 0–39 years under
Externí odkaz:
https://doaj.org/article/985e964515144e92bdd8890ac4733100
Autor:
Katharina Sporbeck, Maximilian L. Haas, Carmen J. Pastor-Maldonado, David S. Schüssele, Catherine Hunter, Zsuzsanna Takacs, Ana L. Diogo de Oliveira, Mirita Franz-Wachtel, Chara Charsou, Simon G. Pfisterer, Andrea Gubas, Patricia K. Haller, Roland L. Knorr, Manuel Kaulich, Boris Macek, Eeva-Liisa Eskelinen, Anne Simonsen, Tassula Proikas-Cezanne
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-23 (2023)
Abstract Human WIPI β-propellers function as PI3P effectors in autophagy, with WIPI4 and WIPI3 being able to link autophagy control by AMPK and TORC1 to the formation of autophagosomes. WIPI1, instead, assists WIPI2 in efficiently recruiting the ATG
Externí odkaz:
https://doaj.org/article/d0288956339a424480d31074800a3152
Autor:
Elena V. Demidova, Ilya G. Serebriiskii, Ramilia Vlasenkova, Simon Kelow, Mark D. Andrake, Tiffiney R. Hartman, Tatiana Kent, James Virtucio, Gail L. Rosen, Richard T. Pomerantz, Roland L. Dunbrack, Erica A. Golemis, Michael J. Hall, David Y. T. Chen, Mary B. Daly, Sanjeevani Arora
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Early-onset renal cell carcinoma (eoRCC) is typically associated with pathogenic germline variants (PGVs) in RCC familial syndrome genes. However, most eoRCC patients lack PGVs in familial RCC genes and their genetic risk remains
Externí odkaz:
https://doaj.org/article/79fe95141ffc4e15bbb6f4e7ed4a8c6d
Autor:
Elena V. Demidova, Ilya G. Serebriiskii, Ramilia Vlasenkova, Simon Kelow, Mark D. Andrake, Tiffiney R. Hartman, Tatiana Kent, James Virtucio, Gail L. Rosen, Richard T. Pomerantz, Roland L. Dunbrack, Erica A. Golemis, Michael J. Hall, David Y. T. Chen, Mary B. Daly, Sanjeevani Arora
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/728682ec991d400ca75db118e2b39608
Autor:
Nancy E. Hernandez, Wojciech Jankowski, Rahel Frick, Simon P. Kelow, Joseph H. Lubin, Vijaya Simhadri, Jared Adolf-Bryfogle, Sagar D. Khare, Roland L. Dunbrack, Jr., Jeffrey J. Gray, Zuben E. Sauna
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e17901- (2023)
Externí odkaz:
https://doaj.org/article/9e85b30d52f24dc1a21cd1acfeca00cb
Autor:
Jason A. Mouabbi, Akshara Singareeka Raghavendra, Roland L. Bassett, Amy Hassan, Debu Tripathy, Rachel M. Layman
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-7 (2022)
Abstract The addition of targeted therapies (TT) to endocrine therapy (ET) has improved the outcomes of patients with HR-positive, HER2-negative metastatic breast cancer (mBC). However, it is unknown whether patients with invasive lobular carcinoma (
Externí odkaz:
https://doaj.org/article/982f3e9cb56b48ee9ecd4add8542b9a0
Autor:
Nancy E. Hernandez, Wojciech Jankowski, Rahel Frick, Simon P. Kelow, Joseph H. Lubin, Vijaya Simhadri, Jared Adolf-Bryfogle, Sagar D. Khare, Roland L. Dunbrack, Jr., Jeffrey J. Gray, Zuben E. Sauna
Publikováno v:
Heliyon, Vol 9, Iss 4, Pp e15032- (2023)
The human infectious disease COVID-19 caused by the SARS-CoV-2 virus has become a major threat to global public health. Developing a vaccine is the preferred prophylactic response to epidemics and pandemics. However, for individuals who have contract
Externí odkaz:
https://doaj.org/article/ce94e33881824004b4d691d4ee80fb5c