Novel Budesonide Suppository and Standard Budesonide Rectal Foam Induce High Rates of Clinical Remission and Mucosal Healing in Active Ulcerative Proctitis: a Randomised, Controlled, Non-inferiority Trial

Autor: Wolfgang Kruis, Britta Siegmund, Konrad Lesniakowski, Vladimir Simanenkov, Ludmila Khimion, Marcin Sobon, Glebs Delmans, Svetlana V Maksyashina, Oleg A Sablin, Juris Pokrotnieks, Yuriy Mostovoy, Olena Datsenko, Sayar Abdulkhakov, Andriy Dorofeyev, Olena Levchenko, Olga Alexeeva, Pavel Andreev, Ivan P Kolesnik, Emese Mihaly, Orest Abrahamovych, Malgorzata Baluta, Nataliia Kharchenko, Neshta Viacheslav, Yury Uspenskiy, Michael Vieth, Ralf Mohrbacher, Ralph Mueller, Roland Greinwald

Publikováno v: Journal of Crohn's and Colitis. 16:1714-1724

Background and Aims Proctitis is the least extensive type of ulcerative colitis, for which rectal therapy is rarely studied and is underused. This study evaluated the efficacy, safety, and patient’s preference of a novel formulation of budesonide s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3794e8633fa89d63de34dc3343619a74
https://doi.org/10.1093/ecco-jcc/jjac081

Budesonide as induction therapy for incomplete microscopic colitis: A randomised, placebo‐controlled multicentre trial

Autor: Andreas Münch, Roland Greinwald, Jordi Guardiola, Ralf Mohrbacher, Daniela E. Aust, Lars Kristian Munck, Ferenc Nagy, Ahmed Madisch, Johan Bohr, Gerd Bouma, Blanca Belloc, Stephan Miehlke, Emese Mihály, Juozas Kupcinskas, Chunliang Shi

Publikováno v: United European Gastroenterology Journal
Münch, A, Mihaly, E, Nagy, F, Madisch, A, Kupčinskas, J, Miehlke, S, Bohr, J, Bouma, G, Guardiola, J, Belloc, B, Shi, C, Aust, D, Mohrbacher, R, Greinwald, R & Munck, L K 2021, ' Budesonide as induction therapy for incomplete microscopic colitis: A randomised, placebo-controlled multicentre trial ', United European Gastroenterology Journal, vol. 9, no. 7, pp. 837-847 . https://doi.org/10.1002/ueg2.12131
Münch, A, Mihaly, E, Nagy, F, Madisch, A, Kupčinskas, J, Miehlke, S, Bohr, J, Bouma, G, Guardiola, J, Belloc, B, Shi, C, Aust, D, Mohrbacher, R, Greinwald, R & Munck, L K 2021, ' Budesonide as induction therapy for incomplete microscopic colitis : A randomised, placebo-controlled multicentre trial ', United European Gastroenterology Journal, vol. 9, no. 7, pp. 837-847 . https://doi.org/10.1002/ueg2.12131
Dipòsit Digital de la UB
Universidad de Barcelona
United European Gastroenterology Journal, 9(7), 837-847. SAGE Publications Inc.

Background and aims: Incomplete microscopic colitis (MCi) is a subtype of microscopic colitis (MC). Budesonide is recommended as a first-line treatment for MC. However, randomised trials on efficacy of treatment in MCi are missing. We therefore perfo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2659d961f7db571839807342e224a9
http://europepmc.org/articles/PMC8435258

Double-Blind, Randomized, Placebo-Controlled Multi-Center Phase III Study Followed by Open-Label Phase on the Efficacy and Tolerability of Budesonide in Patients with Resistant Oral Chronic GVHD: Part 2 – Pain, Subjective Measures and Safety Analysis

Autor: SHARON ELAD, RENATE SCHMELZ, EVA WAGNER, ALBERTO BOSI, JANA BABATZ, RALF MEYER, IRENE DONNINI, DOMINIK HEIM, JÖRG HALTER, DANIEL WOLF WOLFF, MICHAEL KOLDEHOFF, KERSTIN SCHÄFER-ECKARDT, HILDEGARD GREINIX, GUISEPPE IRRERA, GÜLSAN SUCAK, HEDWIG KASPARU, GUIDO KOBBE, ULRICH DUENZINGER, LADISLAV JEBAVY, TIMOTHY MEILLER, JOEL EPSTEIN, YEHUDA ZADIK, RALF MOHRBACHER, ROLAND GREINWALD, MICHAEL SHAPIRA

Publikováno v: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 135:e43-e44

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3512002eba18cffe54b1524f30d3c3a4
https://doi.org/10.1016/j.oooo.2022.09.029

Distribution of histopathological features along the colon in microscopic colitis

Autor: Ralf Mohrbacher, Stephan Miehlke, Roland Greinwald, Anne-Marie Kanstrup Fiehn, Ralph Mueller, Ahmed Madisch, Ole K. Bonderup, Tanju Nacak, Andreas Münch, Michael Vieth, Fernando Fernández-Bañares, Lars Kristian Munck, Daniela E. Aust, Emese Mihály, Juozas Kupcinskas

Publikováno v: Fiehn, A-M K, Miehlke, S, Aust, D, Vieth, M, Bonderup, O, Fernández-Bañares, F, Mihaly, E, Kupcinskas, J, Madisch, A, Munck, L K, Nacak, T, Mohrbacher, R, Mueller, R, Greinwald, R & Münch, A 2021, ' Distribution of histopathological features along the colon in microscopic colitis ', International Journal of Colorectal Disease, vol. 36, no. 1, pp. 151-159 . https://doi.org/10.1007/s00384-020-03747-z

PURPOSE: The diagnosis microscopic colitis (MC) consisting of collagenous colitis (CC) and lymphocytic colitis (LC) relies on histological assessment of mucosal biopsies from the colon. The optimal biopsy strategy for reliable diagnosis of MC is cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68975f72b9e385441d6e24eaa430874e
https://doi.org/10.1007/s00384-020-03747-z

Eine 12-wöchige Induktionstherapie mit der Budesonid-Schmelztablette führt zu einer signifikanten Verbesserung sowohl der inflammatorischen als auch der fibrotischen endoskopischen Zeichen bei Erwachsenen mit aktiver eosinophiler Ösophagitis und inkompletter Response nach 6 Wochen

Autor: S Miehlke, Alfredo J. Lucendo, Stephan I. Brückner, Christoph Schlag, Roland Greinwald, Alain M. Schoepfer, Stefan Schubert, Christoph Schmöcker, R Müller, U von Arnim, Stephen Attwood, Ahmed Madisch, A. Straumann

Publikováno v: Viszeralmedizin 2021 Gemeinsame Jahrestagung Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS), Sektion Endoskopie der DGVS, Deutsche Gesellschaft für Allgemein und Viszeralchirurgie (DGAV).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b9f89d1cb69efc7f64bed34be386449
https://doi.org/10.1055/s-0041-1733503