Zobrazeno 1 - 10
of 29
pro vyhledávání: '"ROGER BURGUS"'
Autor:
Roger Burgus, Madalyn Butcher, Wylie Vale, Catherine Rivier, Jose Villarreal, Paul Brazeau, Marvin R. Brown
Publikováno v:
Biochemical and Biophysical Research Communications. 70:551-558
A protein has been isolated from ovine hypothalamus on the basis of its ability to stimulate release of growth hormone by in vitro cultures of dispersed pituitary cells. This protein has been identified as being myelin basic protein. With no similar
Publikováno v:
Psychoneuroendocrinology. 2:59-62
(1) α-, β-, γ-endorphins have primary structures respectively identical to those of β-lipotropin subunits [61–76], [61–91], [61–77]. (2) These peptides exhibit opiate-like activity in several assay systems. (3) A series of analogs of the na
Publikováno v:
Biochemistry. 12:5305-5310
Autor:
Nicholas Ling, Richard E. Blackwell, Jean Rivier, Madalyn Butcher, Wylie Vale, M. Monahan, Max S. Amoss, Robert E. Fellows, Roger Guillemin, Roger Burgus
Publikováno v:
Proceedings of the National Academy of Sciences. 69:278-282
The primary structure of ovine hypothalamic hypophysiotropic luteinizing hormone-releasing factor, LRF, has been established as pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH 2 by hydrolysis of the peptide with chymotrypsin or pyrrolidone-carboxylylpept
Autor:
Roger Guillemin, Roger Burgus
Publikováno v:
Annual Review of Biochemistry. 39:499-526
Publikováno v:
Neuroendocrinology. 3:34-46
Publikováno v:
Proceedings of the National Academy of Sciences. 70:684-688
Somatostatin, a peptide isolated from ovine hypothalamic tissue that inhibits the release of radioimmunoassayable growth hormone in vitro from rat or human pituitary cells or in vivo in rats, has the primary structure [Formula: see text]. The structu
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 31:109-112
Intravenous administration of synthetic TRF in doses of 250–750 μg stimulates a rise in plasma HTSH levels in normal individuals. No rise in plasma HTSH occurs following 500–750 μg of TRF in subjects on 0.3 mg of Lthyroxine or in patients with
Publikováno v:
Biochemical and Biophysical Research Communications. 44:205-210
Summary A purification sequence for the ovine hypothalamic LH-releasing factor is reported. From 300,000 sheep brains, ca. 200 μg have been obtained of a material containing ⪯ 56% peptide, of which 94% can be accounted for by the amino acids His 1
Publikováno v:
Endocrinology. 89:1485-1488
A series of synthetic analogues of TRF (thyrotropin releasing factor, pGlu-His-Pro-NH2) have been tested for biological activity. As part of this series, two dipeptide and two tripeptide derivatives were prepared which had a single methyl group on on