Effect of phosphorylation on a human-like osteopontin peptide

Autor: Victoria García Sakai, Samuel Lenton, Roger A. Clegg, Michael Härtlein, Carl Holt, Tilo Seydel, Marco Grimaldo, Tommy Nylander, Felix Roosen-Runge, Frank Schreiber, Susana C. M. Teixeira

Publikováno v: Biophysical Journal
Biophysical Journal, Biophysical Society, 2017, 112 (8), pp.1586-1596. ⟨10.1016/j.bpj.2017.03.005⟩
'Biophysical Journal ', vol: 112, pages: 1586-1596 (2017)

International audience; The last decade established that the dynamic properties of the phosphoproteome are central to function and its modulation. The temporal dimension of phosphorylation effects remains nonetheless poorly understood, particularly f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce1f1b7b574a6cd9e509cad40006ca9
https://eprints.gla.ac.uk/140710/1/140710.pdf

Characterisation of the N′1 isoform of the cyclic AMP-dependent protein kinase (PK-A) catalytic subunit in the nematode, Caenorhabditis elegans

Autor: Annalise V. Bicknell, Laura C. Bowen, Roger A. Clegg, Mohammad Tabish, Huw H. Rees, Michael J. Fisher, Mark C. Prescott

Publikováno v: Archives of Biochemistry and Biophysics. 519:38-45

Multiple isoforms of the cyclic AMP-dependent protein kinase (PK-A) catalytic (C) subunit, arise as a consequence of the use of alternative splicing strategies during transcription of the kin-1 gene in the nematode, Caenorhabditis elegans. N-myristoy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769f87a8bfdf2d497ab3866e32a38ecd
https://doi.org/10.1016/j.abb.2012.01.008

Characterisation of an N-terminal variant of acetyl-CoA carboxylase-α: expression in human tissues and evolutionary aspects

Autor: Nigel T. Price, Michael C. Barber, Amanda J. Vallance, Roger A. Clegg, R.Y. Thomson, Maureen T. Travers

Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1634:97-106

mRNA encoding a variant acetyl-CoA carboxylase (ACC)-alpha isozyme, transcribed from a downstream promoter, PIII, was detected in human tissues. Such exon 5A-containing transcripts (E5A-mRNA) encode ACC-alpha with a distinct N-terminus, with 15/17 re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4281ce6532378ad79f5d66daa3f2c90
https://doi.org/10.1016/j.bbalip.2003.09.005

Organization and alternative splicing of the Caenorhabditis elegans cAMP-dependent protein kinase catalytic-subunit gene (kin-1)

Autor: Mohammad Tabish, Huw H. Rees, Michael Fisher, Roger A. Clegg

Publikováno v: Biochemical Journal. 339:209-216

The cAMP-dependent protein kinase (protein kinase A, PK-A) is multifunctional in nature, with key roles in the control of diverse aspects of eukaryotic cellular activity. In the case of the free-living nematode, Caenorhabditis elegans, a gene encodin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::741ce8d1b96f28b415d5075de5d099e7
https://doi.org/10.1042/bj3390209

Phorbol ester and diacylglycerol activation of native protein kinase C species from various tissues

Autor: Kevin Connor, Roger A. Clegg, Melanie S. Johnson, Rory Mitchell, David J. MacEwan, James Simpson, Angela J. Ison

Publikováno v: Molecular and Cellular Biochemistry. 146:127-137

The characteristics of PKC activation induced by a number of compounds were investigated using PKCs, partially-purified from sources with a naturally high abundance of certain Ca2+ dependent PKC isoforms. Native isoforms were used rather than PKC iso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be28e7f46e162fe335086274bfdce301
https://doi.org/10.1007/bf00944605