Zobrazeno 1 - 10
of 1 065
pro vyhledávání: '"ROCK2"'
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract The Rho GTPase signaling pathway is responsible for cell-specific processes, including actin cytoskeleton organization, cell motility, cell division, and the transcription of specific genes. The implications of RhoA and the downstream effect
Externí odkaz:
https://doaj.org/article/b34eb8627a054c44a41af5e1628e9554
Autor:
Ying Wang, Depei Wu, Xiang Zhang, Yuhua Li, Yanjie He, Qifa Liu, Li Xuan, Zhenyu Li, Kunming Qi, Yuqian Sun, Shunqing Wang, Wenjian Mo, Lei Gao, Ye Hua, Yu Wang, Ying Zhang
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Chronic graft-versus-host disease (cGVHD) is an immune-related disorder that is the most common complication post-allogenic hematopoietic stem cell transplant. Corticosteroids with or without calcineurin inhibitors (CNIs) remain t
Externí odkaz:
https://doaj.org/article/89ae62927273414496e688973dfd1906
Akademický článek
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Autor:
Xi‐Xi Li, Jia‐Kun Xu, Wei‐Jie Su, Hong‐Lin Wu, Kun Zhao, Chang‐Ming Zhang, Xiang‐Kun Chen, Li‐Xuan Yang
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 2, Pp 161-174 (2024)
Abstract Temozolomide (TMZ) resistance presents a significant challenge in the treatment of gliomas. Although lysine demethylase 4A (KDM4A) has been implicated in various cancer‐related processes, its role in TMZ resistance remains unclear. This st
Externí odkaz:
https://doaj.org/article/c53c18a5173743f79d4628eec81121c0
Publikováno v:
Journal of Physiological Sciences, Vol 74, Iss 1, Pp 1-15 (2024)
Abstract Background Sepsis-induced acute lung injury (ALI) accounts for about 40% of ALI, accompanied by alveolar epithelial injury. The study aimed to reveal the role of circular RNA_0114428 (circ_0114428) in sepsis-induced ALI. Methods Human pulmon
Externí odkaz:
https://doaj.org/article/f6c72c7447b34667b01db5a72e516669
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 39, Iss 7, Pp 675-687 (2023)
Abstract Myocardial ischemia–reperfusion injury (MIRI) was often observed after surgeries, causing a lot of suffering to patients. Inflammation and apoptosis were critical determinants during MIRI. We conveyed experiments to reveal the regulatory f
Externí odkaz:
https://doaj.org/article/1d2329d364234dafac17b14d4d03f81e
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
Background: Nonalcoholic fatty liver disease (NAFLD) is the most common hepatic disorders worldwide. The mitophagy is suggested to be repressed in NAFLD, but the mechanism remains to be elucidated. Methods: NAFLD cell and mouse models were establishe
Externí odkaz:
https://doaj.org/article/22cb7b9d79444cb5a42e22dcb4401a15
Publikováno v:
Journal of Investigative Surgery, Vol 36, Iss 1 (2023)
Objective: Septic patients are especially vulnerable to acute lung injury (ALI). Calycosin (CAL) has various promising pharmacological activities. This paper aims to expound on the role of CAL in mice with sepsis-induced ALI and the associated mechan
Externí odkaz:
https://doaj.org/article/83e001dc6d5b447185deecd4f85d7540
Publikováno v:
Adipocyte, Vol 12, Iss 1 (2023)
ABSTRACTThe healing of skin wounds is a highly coordinated multi-step process that occurs after trauma including surgical incisions, thermal burns, and chronic ulcers. In this study, the authors investigated lncRNA FOXD2-AS1 function in adipose mesen
Externí odkaz:
https://doaj.org/article/2b2b31181a3545a6be60a2430693cf71
Autor:
Giovanni Fulvio, Chiara Baldini, Marta Mosca, Antonello di Paolo, Guido Bocci, Giuseppe Alberto Palumbo, Emma Cacciola, Paola Migliorini, Rossella Cacciola, Sara Galimberti
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
In this article, we reviewed the possible mechanisms linking the clonal hematopoiesis of indeterminate potential (CHIP) to chronic myeloproliferative neoplasms (MPNs), autoimmune diseases (ADs), and cardiovascular diseases (CADs). CHIP is characteriz
Externí odkaz:
https://doaj.org/article/c74c4682f9b84b2ca560a46b7004c88c