Zobrazeno 1 - 10
of 24
pro vyhledávání: '"ROCK, Rho kinase"'
Autor:
Kaatje Lenaerts, Joep Grootjans, Anna M. Kip, Marco Manca, Steven W.M. Olde Damink, Bas Boonen, Cornelis H. C. Dejong, Wim A. Buurman, M'hamed Hadfoune, Joep P. M. Derikx, Erik A.L. Biessen
Publikováno v:
CMGH, 13(3), 681-694. Elsevier Inc.
Cellular and Molecular Gastroenterology and Hepatology : CMGH 13(3), 681-694 (2022). doi:10.1016/j.jcmgh.2021.11.001
Cellular and molecular gastroenterology and hepatology, 13(3), 681-694. Elsevier Inc.
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology : CMGH 13(3), 681-694 (2022). doi:10.1016/j.jcmgh.2021.11.001
Cellular and molecular gastroenterology and hepatology, 13(3), 681-694. Elsevier Inc.
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Intestinal ischemia-reperfusion injury is a serious and life-threatening condition. A better understanding of molecular mechanisms related to intestinal ischemia-reperfusion injury in human beings is imperative to find therapeutic t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ba4ffc78867321b72f85db21a76d04
http://www.scopus.com/inward/record.url?scp=85121206348&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85121206348&partnerID=8YFLogxK
Autor:
Yueshui Zhao, Shengpeng Wang, Jun Pang, Bin Wei, Fukuan Du, Parham Jabbarzadeh Kaboli, Qinglian Wen, Xiaoxiao Wu, Mingxing Li, Xu Wu, Zhangang Xiao, Qijie Zhao, Meijuan Chen, Yitao Wang, Jing Li, Chi Hin Cho, Jing Shen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1360-1381 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Long-term primary culture of mammalian cells has been always difficult due to unavoidable senescence. Conventional methods for generating immortalized cell lines usually require manipulation of genome which leads to change of important biological and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a64733f7c067f16e149ca513254392a
http://www.sciencedirect.com/science/article/pii/S2211383519311153
http://www.sciencedirect.com/science/article/pii/S2211383519311153
Publikováno v:
Regenerative Therapy
Regenerative Therapy, Vol 12, Iss, Pp 20-26 (2019)
Regenerative Therapy, Vol 12, Iss, Pp 20-26 (2019)
Introduction Maintaining the pluripotency and homogeneity of human induced pluripotent stem cells (hiPSCs) requires stable culture conditions with consistent medium change. In this study, we evaluated the performance of medium change by machine vs. m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3b9fa6c398592f2cba5384b26533b4
https://pubmed.ncbi.nlm.nih.gov/31890763
https://pubmed.ncbi.nlm.nih.gov/31890763
Autor:
Maria Fernanda de Paula Werner, Karin Scheschowitsch, Jamil Assreuy, Luisa Mota da Silva, Priscila de Souza, José Eduardo da Silva-Santos, Karla L. Guarido
Publikováno v:
Redox Biology, Vol 10, Iss C, Pp 140-147 (2016)
Redox Biology
Redox Biology
We investigated long-lasting changes in endothelial and vascular function in adult rat survivors of severe sepsis induced by cecal ligation and puncture (CLP) model. For this, male Wistar rats (200–350 g) had their cecum punctured once (non-transfi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f683d0498c4a1ae5e694f26e46daa2d5
http://www.sciencedirect.com/science/article/pii/S2213231716301409
http://www.sciencedirect.com/science/article/pii/S2213231716301409
Publikováno v:
Biochemical Journal
Rho GTPases are critical for platelet function. Although the roles of RhoA, Rac and Cdc42 are characterized, platelets express other Rho GTPases, whose activities are less well understood. This review summarizes our understanding of the roles of plat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8dee12c58f70730a3a55910e7d6987a6
http://europepmc.org/articles/PMC4357237
http://europepmc.org/articles/PMC4357237
Autor:
Michelle Peckham, Kirsten Riches, Marlys L. Koschinsky, Matthew Adams, Stephen G. Ball, Philip Warburton, Karen E. Porter, Neil A. Turner, Larissa Franklin, Azhar Maqbool, David J. O'Regan, Jacquelyn Bond, Nicole T. Feric
Publikováno v:
The International Journal of Biochemistry & Cell Biology
Graphical abstract
Highlights • Acute application of apo(a) to smooth muscle cells induced chemorepulsion. • Chronic application (>24 h) induced stress fibre formation and cell spreading. • Effects of apo(a) were mediated by integrin αVβ
Highlights • Acute application of apo(a) to smooth muscle cells induced chemorepulsion. • Chronic application (>24 h) induced stress fibre formation and cell spreading. • Effects of apo(a) were mediated by integrin αVβ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b2df38c175b6a8a1ca877d409722a4a
Autor:
Maria Deak, Dario R. Alessi, Nicolas Dzamko, Fayçal Hentati, Alan R. Prescott, R. Jeremy Nichols, Alastair D. Reith
Publikováno v:
Biochemical Journal
LRRK2 (leucine-rich repeat protein kinase 2) is mutated in a significant number of Parkinson's disease patients. Since a common mutation that replaces Gly2019 with a serine residue enhances kinase catalytic activity, small-molecule LRRK2 inhibitors m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71374cd2d22b2908102a9ec439d4eb39
https://doi.org/10.1042/bj20100784
https://doi.org/10.1042/bj20100784
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Haifei Zhang, Patricia Murray, Kristina L. Parry, Daniel J. Antoine, David Edgar, Nicola Wells, Isabel Hopp, Andrew I. Cooper, Robert D. Short, Marina Prewitz
Publikováno v:
The International Journal of Biochemistry & Cell Biology
Mouse embryonic stem cells (mESCs) undergo self-renewal in the presence of the cytokine, leukaemia inhibitory factor (LIF). Following LIF withdrawal, mESCs differentiate, and this is accompanied by an increase in cell-substratum adhesion and cell spr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01496d31fdb676561c915c496b88e806