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pro vyhledávání: '"ROCH, SEBASTIEN"'
Understanding size and scale (USS) and order-of-magnitude reasoning (OMR) are critical for scientific literacy. This study examines an educational approach to enhance these skills in high school science, considering the cognitive prerequisites and ch
Externí odkaz:
http://arxiv.org/abs/2405.16480
Autor:
Roch, Sebastien
Recent work on dissimilarity-based hierarchical clustering has led to the introduction of global objective functions for this classical problem. Several standard approaches, such as average linkage, as well as some new heuristics have been shown to p
Externí odkaz:
http://arxiv.org/abs/2207.14375
Autor:
Legried, Brandon, Roch, Sebastien
Ancestral sequence reconstruction is a key task in computational biology. It consists in inferring a molecular sequence at an ancestral species of a known phylogeny, given descendant sequences at the tip of the tree. In addition to its many biologica
Externí odkaz:
http://arxiv.org/abs/2207.12543
In applied multivariate statistics, estimating the number of latent dimensions or the number of clusters is a fundamental and recurring problem. One common diagnostic is the scree plot, which shows the largest eigenvalues of the data matrix; the user
Externí odkaz:
http://arxiv.org/abs/2108.03336
Publikováno v:
Annals of applied probability, 2022
We consider phylogeny estimation under a two-state model of sequence evolution by site substitution on a tree. In the asymptotic regime where the sequence lengths tend to infinity, we show that for any fixed $k$ no statistically consistent phylogeny
Externí odkaz:
http://arxiv.org/abs/2010.14460
We consider species tree estimation under a standard stochastic model of gene tree evolution that incorporates incomplete lineage sorting (as modeled by a coalescent process) and gene duplication and loss (as modeled by a branching process). Through
Externí odkaz:
http://arxiv.org/abs/2007.06697
Publikováno v:
Bulletin of Mathematical Biology. Vol 82 (9), 2020
We consider the problem of distance estimation under the TKF91 model of sequence evolution by insertions, deletions and substitutions on a phylogeny. In an asymptotic regime where the expected sequence lengths tend to infinity, we show that no consis
Externí odkaz:
http://arxiv.org/abs/2005.11625
Akademický článek
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Autor:
Roch, Sebastien
Publikováno v:
RECOMB-CG 2018
We consider the problem of estimating species trees from unrooted gene tree topologies in the presence of incomplete lineage sorting, a common phenomenon that creates gene tree heterogeneity in multilocus datasets. One popular class of reconstruction
Externí odkaz:
http://arxiv.org/abs/1812.08357
Respondent-driven sampling (RDS) is a popular approach to study marginalized or hard-to-reach populations. It collects samples from a networked population by incentivizing participants to refer their friends into the study. One major challenge in ana
Externí odkaz:
http://arxiv.org/abs/1812.01188