Zobrazeno 1 - 10
of 203
pro vyhledávání: '"ROBERT T. SCHIMKE"'
Autor:
Rakesh C. Sharma, Robert T. Schimke
Publikováno v:
BioTechniques, Vol 20, Iss 1, Pp 42-44 (1996)
Externí odkaz:
https://doaj.org/article/4765a74e8c50486ea8462c9a10bc91b6
Autor:
Enrico Mihich, Robert T. Schimke
The fifth Annual Pezcoller Symposium entitled, Apoptosis, was held in Trento, Italy, June 9-1I, 1993 and was focused on the specific phenomena leading to Programmed Cell Death (PCD) or Apoptosis, and the mechanisms involved. With presentations at the
Publikováno v:
Analytical Biochemistry. 235:195-201
The tetracycline-controlled gene expression system utilizes the control elements of the tetracycline resistance operon encoded in TnlO of Escherichia coli to control gene expression in eukaryotic cells. Here we demonstrate the quantitative control of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b98b77c76876c5defc672a27a4f61e7
https://doi.org/10.1006/abio.1996.0112
https://doi.org/10.1006/abio.1996.0112
Publikováno v:
Proceedings of the National Academy of Sciences. 93:1238-1242
P-glycoprotein (Pgp), a transmembrane efflux pump encoded by the MDR1 gene, transports various lipophilic drugs that enter the cell by passive diffusion through the lipid bilayer. Pgp-expressing multidrug-resistant cell lines are not usually cross-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8a6fb9b9189115de7113f4bcabb074
https://doi.org/10.1073/pnas.93.3.1238
https://doi.org/10.1073/pnas.93.3.1238
Publikováno v:
Experimental Cell Research. 219:159-168
We have studied the effect of the cell synchronization agents compactin, ciclopirox olamine, mimosine, aphidicolin, ALLN, and colcemid on several parameters of cell cycle progression in mitotically synchronized HeLa S3 cells. Using cell size and cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a525f305a3666d086626c82d4068002
https://doi.org/10.1006/excr.1995.1216
https://doi.org/10.1006/excr.1995.1216
Autor:
Randy Legerski, Pamela S. Russell, Adam Sartiel, Roger L. Eddy, Yael Ziv, Robert T. Schimke, Anat Bar-Shira, Manuel Buchwald, Yosef Shiloh, Timothy J. Jorgensen, Thomas B. Shows
Publikováno v:
Somatic Cell and Molecular Genetics. 21:99-111
Genes responsible for genetic diseases with increased sensitivity to DNA-damaging agents can be identified using complementation cloning. This strategy is based on in vitro complementation of the cellular sensitivity by gene transfer. Ataxia-telangie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36e5340335c060cf6d08abeca4f10d7
https://doi.org/10.1007/bf02255785
https://doi.org/10.1007/bf02255785
Publikováno v:
Experimental Cell Research. 215:373-379
We have studied the relationship between apoptosis and drug-induced cell cycle perturbation in HeLa S3 cells when treated with the anti-tubulin drug colcemid. We found that at least two distinct mechanisms contributed to colcemid cytotoxicity and apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6f2172e05d6e773296c28dfc62c3eb
https://doi.org/10.1006/excr.1994.1354
https://doi.org/10.1006/excr.1994.1354
Publikováno v:
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 345:311-317
HeLaS3 cells undergo apoptosis after 18-24 h of cell cycle stasis irrespective of the agent employed (colcemid, aphidicolin, cis-platin). At high drug concentrations apoptosis occurs in cells arrested in the cell cycle in which the drug is applied an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c25a48c4a54c7f7f6eec8376db5b288c
https://doi.org/10.1098/rstb.1994.0111
https://doi.org/10.1098/rstb.1994.0111
Publikováno v:
Experimental Cell Research. 211:275-281
Using a procedure to stain cells simultaneously for cyclin B1 protein and DNA, we have examined cyclin B1 expression by flow cytometry in human cells under a variety of perturbing and nonperturbing conditions. The method described is useful for measu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e6b17c02d8646aad0d22d64b621aa4
https://doi.org/10.1006/excr.1994.1087
https://doi.org/10.1006/excr.1994.1087
Publikováno v:
Journal of Biological Chemistry. 268:23072-23080
We have shown previously that there are significant differences between mammalian cell lines in response to disruption of the assembly of the mitotic spindle apparatus (Kung, A. L., Sherwood, S. W., and Schimke, R. T. (1990) Proc. Natl. Acad. Sci. U.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::582a276b3597b7d1329e5a530a2962be
https://doi.org/10.1016/s0021-9258(19)49427-1
https://doi.org/10.1016/s0021-9258(19)49427-1