Zobrazeno 1 - 10 of 67 pro vyhledávání: '"ROBERT SELLERS"'
1
Akademický článek
The small inhibitor WM-1119 effectively targets KAT6A-rearranged AML, but not KMT2A-rearranged AML, despite shared KAT6 genetic dependency
Autor: Mathew Sheridan, Muhammad Ahmad Maqbool, Anne Largeot, Liam Clayfield, Jingru Xu, Natalia Moncaut, Robert Sellers, Jessica Whittle, Jerome Paggetti, Mudassar Iqbal, Romain Aucagne, Laurent Delva, Syed Murtuza Baker, Michael Lie-a-Ling, Valerie Kouskoff, Georges Lacaud
Publikováno v: Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-18 (2024)
Abstract Background The epigenetic factors KAT6A (MOZ/MYST3) and KMT2A (MLL/MLL1) interact in normal hematopoiesis to regulate progenitors’ self-renewal. Both proteins are recurrently translocated in AML, leading to impairment of critical different
Externí odkaz: https://doaj.org/article/9e06903917c740ddb71ed8f77ed9c4dd
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2
Akademický článek
A KRAS-responsive long non-coding RNA controls microRNA processing
Autor: Lei Shi, Peter Magee, Matteo Fassan, Sudhakar Sahoo, Hui Sun Leong, Dave Lee, Robert Sellers, Laura Brullé-Soumaré, Stefano Cairo, Tiziana Monteverde, Stefano Volinia, Duncan D. Smith, Gianpiero Di Leva, Francesca Galuppini, Athanasios R. Paliouras, Kang Zeng, Raymond O’Keefe, Michela Garofalo
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Wild-type KRAS amplification is known to induce KRAS activation in cancer leading to poor prognostic outcomes. Here the authors identify a KRAS-responsive lncRNA, KIMAT1 that maintains KRAS signalling in lung cancer, suggesting that its targeting may
Externí odkaz: https://doaj.org/article/befd75df391041c7bcbc529acaf3af0c
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3
Akademický článek
Eating behaviors and related cultural attitudes of African American men and women
Autor: Christina Oney, Daniel DePaulo, Rebecca Lewis, Robert Sellers
Publikováno v: Health Psychology Open, Vol 2 (2015)
Cultural groups often participate in traditions and activities surrounding food and eating, which contribute to group differences in maladaptive eating-related patterns and outcomes. This study explored the relationships between cultural attitudes an
Externí odkaz: https://doaj.org/article/248c939ddab049e6a6a0887914b95eb0
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