Zobrazeno 1 - 10
of 201
pro vyhledávání: '"ROBERT A. PHILIBERT"'
Autor:
Steven R. H. Beach, Mei Ling Ong, Man-Kit Lei, Sierra E. Carter, Ronald L. Simons, Frederick X. Gibbons, Robert A. Philibert
Publikováno v:
Epigenetics, Vol 17, Iss 9, Pp 982-1002 (2022)
Methylation of FKBP5 is involved in the regulation of the stress response and is influenced by early stress exposure. Two CpG sites, cg20813374 and cg00130530, have been identified as potential reporters of early stress. We examined whether FKBP5 met
Externí odkaz:
https://doaj.org/article/6793196c326c4243963c2c59f9ff723f
Autor:
Ronald L. Simons, Man-Kit Lei, Sierra Carter, Steven R.H. Beach, Frederick X. Gibbons, Meg Gerrard, Robert A. Philibert
Publikováno v:
SSM: Population Health, Vol 7, Iss , Pp - (2019)
Objective: Chronic inflammation and expression of the TP53 gene are two biomarkers that have been identified as particularly important in the etiology and progression of cancer. While much is known about the determinants of inflammation, there is cur
Externí odkaz:
https://doaj.org/article/a98f463a3dfb4dbf8c89b9c7c7e37203
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Differential methylation at MTHFR (mMTHFR) has been examined previously as a moderator of changes in methylation among nascent smokers, but the effects of mMTHFR on genomewide patterns of methylation among established smokers in middle age are unknow
Externí odkaz:
https://doaj.org/article/988c0cc067c34b43beda3f0c729de5f1
Publikováno v:
Frontiers in Psychology, Vol 6 (2015)
The current investigation was designed to examine the association of parenting during late childhood and early adolescence, a time of rapid physical development, with biological propensity for inflammation. Based on life course theory, it was hypothe
Externí odkaz:
https://doaj.org/article/0e8d55585cfb4db89ac9caee39d33b16
Publikováno v:
Frontiers in Genetics, Vol 3 (2012)
Peripheral mononuclear cell preparations are commonly used as proxies for other tissues, such as brain, in studies of the role of gene expression and methylation in human disease. Using these materials, a number of investigators have demonstrated tha
Externí odkaz:
https://doaj.org/article/e6d36d2a6726452e81747d5f9afe457c
Autor:
Robert A. Philibert, Rachel A. Reimer, Eric A. Hoffman, Allan M. Andersen, Kelsey Dawes, Shelly Miller, James A. Mills, Jeffrey D. Long
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Numerous studies have shown that cg05575921 methylation decreases in response to smoking. However, secondary to methodological issues, the magnitude and dose dependency of that response is as of yet unclear. This lack of certainty is a barrier to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0877794ea9c0c8b4d26e1bc03391e1
https://doaj.org/article/f9a2397189974920a5250144371a2f3c
https://doaj.org/article/f9a2397189974920a5250144371a2f3c
Autor:
Steven R. H. Beach, Eric T. Klopack, Sierra E. Carter, Robert A. Philibert, Ronald L. Simons, Frederick X. Gibbons, Mei Ling Ong, Meg Gerrard, Man-Kit Lei
Publikováno v:
International Journal of Environmental Research and Public Health; Volume 19; Issue 20; Pages: 13421
In a sample of 685 late middle-aged Black adults (M age at 2019 = 57.17 years), we examined the effects of loneliness and per capita income on accelerated aging using a newly developed DNA-methylation based index: the DunedinPACE. First, using linear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d16fae1425c2406dc39f902257a3aa71
Publikováno v:
Epigenomics
Aim: The Framingham Risk Score (FRS) and atherosclerotic cardiovascular disease (ASCVD) Pooled Cohort Equation (PCE) for predicting risk for incident coronary heart disease (CHD) work poorly. To improve risk stratification for CHD, we developed a nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a72607b8a1b775227181fc89e7fb8bf
https://doi.org/10.2217/epi-2021-0123
https://doi.org/10.2217/epi-2021-0123
Autor:
Steven R. H. Beach, Mei Ling Ong, Frederick X. Gibbons, Meg Gerrard, Man-Kit Lei, Kelsey Dawes, Robert A. Philibert
Publikováno v:
Genes; Volume 13; Issue 10; Pages: 1888
Excessive alcohol consumption (EAC) has a generally accepted effect on morbidity and mortality, outcomes thought to be reflected in measures of epigenetic aging (EA). As the association of self-reported EAC with EA has not been consistent with these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d61b46167d565c361f627bfac8785e32
https://pubmed.ncbi.nlm.nih.gov/36292773
https://pubmed.ncbi.nlm.nih.gov/36292773
Autor:
Ronald L. Simons, Paulo B Pinho, Jeffrey D. Long, Timur Dogan, Douglas Ingle, Frederick X. Gibbons, James A. Mills, Steven R. H. Beach, Kelsey Dawes, Meg Gerrard, Robert A. Philibert, Meeshanthini V. Dogan
Publikováno v:
Epigenetics
Mortality assessments are conducted for both civil and commercial purposes. Recent advances in epigenetics have resulted in DNA methylation tools to assess risk and aid in this task. However, widely available array-based algorithms are not readily tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bdc9004bb108e12aa6e1d32606c0c4f
https://doi.org/10.1080/15592294.2020.1841874
https://doi.org/10.1080/15592294.2020.1841874