Synthesis, biophysical properties, and RNase H activity of 6’-difluoro[4.3.0]bicyclo-DNA

Autor: Sibylle Frei, Adam K. Katolik, Christian J. Leumann

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 79-88 (2019)

Here we present the synthesis, the biophysical properties, and the RNase H profile of 6’-difluorinated [4.3.0]bicyclo-DNA (6’-diF-bc4,3-DNA). The difluorinated thymidine phosphoramidite building block was synthesized starting from an already know

Externí odkaz: https://doaj.org/article/e3084aaa34c649f890b890cf33cef2e4

An enzyme-initiated DNAzyme motor for RNase H activity imaging in living cell

Autor: Namin Hu, Qiaoqin Yu, Manman He, Chuan Zhao, Ting-Ting Chen, Juan Zhang, Yafang Wang, Xia Chu, Cunpeng Nie, Chang Liu

Publikováno v: Chemical Communications. 56:639-642

In this work, we have developed a novel DNAzyme motor initiated by endogenous enzyme for sensitive imaging of intracellular RNase H activity.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68e18c74c8bf2e2679f195c89e1a274
https://doi.org/10.1039/c9cc08692g

Ilimaquinone and 5-epi-Ilimaquinone: Beyond a Simple Diastereomeric Ratio, Biosynthetic Considerations from NMR-Based Analysis

Autor: Erwan Poupon, Sylvain Petek, David Lachkar, Mehdi A. Beniddir, Cécile Debitus, Dirk Erpenbeck, Asmaa Boufridi, Laurent Evanno

Publikováno v: Australian Journal of Chemistry
Australian Journal of Chemistry, CSIRO Publishing, 2017, ⟨10.1071/CH16455⟩
Australian Journal of Chemistry, CSIRO Publishing, 2017, 70 (6), pp.743-750. ⟨10.1071/CH16455⟩

00000; International audience; Dactylospongia metachromia and Dactylospongia elegans collected from French Polynesia were studied with a particular focus on the variation of the diastereomeric ratio between ilimaquinone (4) and 5-epi-ilimaquinone (5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5155b02e0cccfef18aea79ae16d3771
https://hal.archives-ouvertes.fr/hal-01483154

Iridium(iii) complexes with 1,10-phenanthroline-based N^N ligands as highly selective luminescent G-quadruplex probes and application for switch-on ribonuclease H detection

Autor: Tian-Shu Kang, Lihua Lu, Chung-Hang Leung, Chao Yang, Wanhe Wang, Dik-Lung Ma

Publikováno v: Journal of Materials Chemistry B. 4:6791-6796

A systematic study was performed to investigate the relationship between molecular structure and G-quadruplex sensing ability for a series of structurally related cyclometallated iridium(iii) complexes. The novel complex 7 was used to construct a lab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39810083e7566e8187df9633c37a4371
https://doi.org/10.1039/c6tb02316a

Chemical Synthesis of Boranophosphate Deoxy-ribonucleotides

Autor: Takeshi Wada, Yohei Nukaga

Publikováno v: Synthesis of Therapeutic Oligonucleotides ISBN: 9789811319112

Boranophosphate deoxyribonucleotides, in which a non-bridging oxygen atom of each phosphodiester internucleotidic linkage is replaced by a BH3 group, are useful as therapeutic agents owing to affinity for complementary RNA, nuclease resistance, RNase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f698a2ded627150d53ebbf932610e22
https://doi.org/10.1007/978-981-13-1912-9_16