Zobrazeno 1 - 10
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pro vyhledávání: '"RNP biogenesis"'
Akademický článek
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Autor:
Oeffinger, Marlene, Montpetit, Ben
Publikováno v:
In Current Opinion in Cell Biology June 2015 34:46-53
Autor:
Florence Schlotter, Salim Mérouani, Justine Flayac, Valentyne Kogey, Amani Issa, Maxime Dodré, Alexandra Huttin, Christiane Branlant, Edouard Bertrand, Stéphane Labialle, Franck Vandermoere, Céline Verheggen, Séverine Massenet
Publikováno v:
Nucleic Acids Research. 51:3357-3374
The conserved H/ACA RNPs consist of one H/ACA RNA and 4 core proteins: dyskerin, NHP2, NOP10, and GAR1. Its assembly requires several assembly factors. A pre-particle containing the nascent RNAs, dyskerin, NOP10, NHP2 and NAF1 is assembled co-transcr
Publikováno v:
In Current Opinion in Cell Biology 2009 21(3):387-393
Autor:
A. Gregory Matera, Rebecca E. Steiner, C. Allie Mills, Benjamin D. McMichael, Laura E. Herring, Eric L. Garcia
Publikováno v:
Frontiers in RNA Research, Vol 2 (2024)
IntroductionMolecular chaperones and co-chaperones are highly conserved cellular components that perform a variety of duties related to the proper three-dimensional folding of the proteome. The web of factors that carries out this essential task is c
Externí odkaz:
https://doaj.org/article/9428fafe243740aeb08226fc03eb62c2
Akademický článek
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Autor:
Ben Montpetit, Marlene Oeffinger
Publikováno v:
Current Opinion in Cell Biology. 34:46-53
RNA biology has recently seen an explosion of data due to advances in RNA sequencing, proteomic, and RNA imaging technologies. In this review, we highlight progress that has been made using these approaches in the area of nuclear RNP biogenesis and e
Publikováno v:
The EMBO Journal. 30:5010-5020
Shq1 is a conserved protein required for the biogenesis of eukaryotic H/ACA ribonucleoproteins (RNPs), including human telomerase. We report the structure of the Shq1-specific domain alone and in complex with H/ACA RNP proteins Cbf5, Nop10 and Gar1.
Publikováno v:
Current opinion in cell biology. 21(3)
Mutations that affect pre-mRNA processing are the cause for many genetic diseases. Most such mutations target cis-acting regulatory sequences in a given transcript, thus preventing its proper maturation. Only recently however, mutations in trans-acti
Autor:
Shpargel, Karl Bryan
The heart of genetics research lies in gaining knowledge and understanding of the effects that gene alterations have on human health and development. Ultimately, a thorough analysis of genetic diseases spanning from mutation identification to protein
Externí odkaz:
http://rave.ohiolink.edu/etdc/view?acc_num=case1152843710