Zobrazeno 1 - 10
of 111
pro vyhledávání: '"RND-efflux pumps"'
Autor:
Anne-Aurélie Lopes, Sol Vendrell-Fernández, Julien Deschamps, Sonia Georgeault, Thomas Cokelaer, Romain Briandet, Jean-Marc Ghigo
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTBacteroides thetaiotaomicron is a prominent member of the human gut microbiota contributing to nutrient exchange, gut function, and maturation of the host’s immune system. This obligate anaerobe symbiont can adopt a biofilm lifestyle, and i
Externí odkaz:
https://doaj.org/article/a1c5e22701f341c6b062da72aadb1c88
Publikováno v:
Frontiers in Drug Discovery, Vol 4 (2024)
Antimicrobial resistance poses an urgent and formidable global public health threat. The escalation of bacterial multidrug resistance to antibiotics has the potential to become a leading cause of global mortality if there is no substantial improvemen
Externí odkaz:
https://doaj.org/article/98b89259e6634792861fe0e8f1549b49
Publikováno v:
Проблемы особо опасных инфекций, Vol 0, Iss 3, Pp 158-163 (2022)
The aim of the study was to identify and compare potential determinants of aminoglycoside resistance in gentamicin susceptible Burkholderia pseudomallei strains.Materials and methods. A bioinformatics analysis of whole genome shotgun sequences of thr
Externí odkaz:
https://doaj.org/article/e5c7cbedff13414783a4ab3951352341
Autor:
Pierpaolo Cacciotto, Andrea Basciu, Francesco Oliva, Giuliano Malloci, Martin Zacharias, Paolo Ruggerone, Attilio V. Vargiu
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 252-260 (2022)
Efflux pumps of the Resistance-Nodulation-cell Division (RND) superfamily contribute to intrinsic and acquired resistance in Gram-negative pathogens by expelling chemically unrelated antibiotics with high efficiency. They are tripartite systems const
Externí odkaz:
https://doaj.org/article/8853a43188d94088885459276f986732
Autor:
Andrea Catte, Venkata K. Ramaswamy, Attilio Vittorio Vargiu, Giuliano Malloci, Andrea Bosin, Paolo Ruggerone
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The secondary transporters of the resistance-nodulation-cell division (RND) superfamily mediate multidrug resistance in Gram-negative bacteria like Pseudomonas aeruginosa. Among these RND transporters, MexB, MexF, and MexY, with partly overlapping sp
Externí odkaz:
https://doaj.org/article/ea91245656ee42d0b21f894ae381c12b
Akademický článek
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Autor:
Haobin Yao, Siu-Ming Yiu
Publikováno v:
BMC Genomics, Vol 20, Iss S10, Pp 1-10 (2019)
Abstract Background Identification of antibiotic resistance genes from environmental samples has been a critical sub-domain of gene discovery which is directly connected to human health. However, it is drawing extraordinary attention in recent years
Externí odkaz:
https://doaj.org/article/4bfa16e611064b93b0993e627ec82934
Autor:
Yongzheng Zhang, Jesus D. Rosado-Lugo, Pratik Datta, Yangsheng Sun, Yanlu Cao, Anamika Banerjee, Yi Yuan, Ajit K. Parhi
Publikováno v:
Antibiotics, Vol 11, Iss 6, p 716 (2022)
Efflux pumps in Gram-negative bacteria such as Pseudomonas aeruginosa provide intrinsic antimicrobial resistance by facilitating the extrusion of a wide range of antimicrobials. Approaches for combating efflux-mediated multidrug resistance involve, i
Externí odkaz:
https://doaj.org/article/cc60c3c1b8bb45ecb9cfd0329a1a77ec
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Yi Yuan, Jesus D. Rosado-Lugo, Yongzheng Zhang, Pratik Datta, Yangsheng Sun, Yanlu Cao, Anamika Banerjee, Ajit K. Parhi
Publikováno v:
Antibiotics, Vol 11, Iss 1, p 30 (2021)
The ability to rescue the activity of antimicrobials that are no longer effective against bacterial pathogens such as Pseudomonas aeruginosa is an attractive strategy to combat antimicrobial drug resistance. Herein, novel efflux pump inhibitors (EPIs
Externí odkaz:
https://doaj.org/article/46998e2c549648709b36af9e2ace4bbf