Zobrazeno 1 - 10
of 264
pro vyhledávání: '"RNAi screening"'
Autor:
Khaista Rahman, Muhammad Jamal, Xi Chen, Wei Zhou, Bin Yang, Yanyan Zou, Weize Xu, Yingying Lei, Chengchao Wu, Xiaojian Cao, Rohit Tyagi, Muhammad Ahsan Naeem, Da Lin, Zeshan Habib, Nan Peng, Zhen F. Fu, Gang Cao
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 20, Iss 6, Pp 1180-1196 (2022)
Mycobacterium tuberculosis is the causative agent of tuberculosis (TB), which is still the leading cause of mortality from a single infectious disease worldwide. The development of novel anti-TB drugs and vaccines is severely hampered by the complica
Externí odkaz:
https://doaj.org/article/df56f89a67224f8494acba6d192a995b
Autor:
Sabine Bachmaier, Matthew K. Gould, Eleni Polatoglou, Radoslaw Omelianczyk, Ana E. Brennand, Maha A. Aloraini, Jane C. Munday, David Horn, Michael Boshart, Harry P. de Koning
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Cyclic AMP signalling in trypanosomes differs from most eukaryotes due to absence of known cAMP effectors and cAMP independence of PKA. We have previously identified four genes from a genome-wide RNAi screen for resistance to the cAMP phosphodiestera
Externí odkaz:
https://doaj.org/article/a23c0cd921084cd7b7799b4ed7628644
Autor:
Yajing Hao, Shuyang Zhang, Changwei Shao, Junhui Li, Guofeng Zhao, Dong-Er Zhang, Xiang-Dong Fu
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-31 (2022)
Abstract Two-dimensional high-throughput data have become increasingly common in functional genomics studies, which raises new challenges in data analysis. Here, we introduce a new statistic called Zeta, initially developed to identify global splicin
Externí odkaz:
https://doaj.org/article/672af65d14284e36a0eed3f2d359708a
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Advanced Science, Vol 7, Iss 17, Pp n/a-n/a (2020)
Abstract Colorectal cancer (CRC) has become a predominant cancer worldwide. To understand the process of carcinogenesis, a short hairpin RNA library screening is employed to search for candidate genes that promote proliferation in the CRC cell line H
Externí odkaz:
https://doaj.org/article/c82f100b30794aa4ae8212b917f4fae3
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/2c81159332ba4ed3b472ade134b17d89
Autor:
Dong-Shan Yu, Tian-Hao Weng, Chen-Yu Hu, Zhi-Gang Wu, Yan-Hua Li, Lin-Fang Cheng, Nan-Ping Wu, Lan-Juan Li, Hang-Ping Yao
Publikováno v:
Frontiers in Microbiology, Vol 10 (2020)
Externí odkaz:
https://doaj.org/article/371cd749d2444f3aadfdba0bd4cc5bdc
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1936 (2021)
Recurrent infection-inflammation cycles in cystic fibrosis (CF) patients generate a highly oxidative environment, leading to progressive destruction of the airway epithelia. The identification of novel modifier genes involved in oxidative stress susc
Externí odkaz:
https://doaj.org/article/74c94b71b3104c3f8ea2fb59f616692b
Autor:
Jangsoon Lee, Huey Liu, Troy Pearson, Toshiaki Iwase, Jon Fuson, Alshad S. Lalani, Lisa D. Eli, Irmina Diala, Debu Tripathy, Bora Lim, Naoto T. Ueno
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 740 (2021)
Human epidermal growth factor receptor (EGFR) 2 (HER2) is overexpressed/amplified in about 25% of all breast cancers, and EGFR is overexpressed in up to 76% and amplified in up to 24% of triple-negative breast cancers (TNBC). Here, we aimed to identi
Externí odkaz:
https://doaj.org/article/cedd88ae516042b3b4bd35ba6d3e15c2