Zobrazeno 1 - 10
of 1 229
pro vyhledávání: '"RNA-seq analysis"'
Autor:
Hongkai Yao, Weifang Tong, Yunping Song, Ruoyu Li, Xuerui Xiang, Wen Cheng, Yunjiao Zhou, Yijing He, Yi Yang, Yunxi Liu, Siguang Li, Lingjing Jin
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract The primary pathological change in Parkinson’s disease (PD) is the progressive degeneration of dopaminergic neurons in the substantia nigra. Additionally, excessive microglial activation and synaptic loss are also typical features observed
Externí odkaz:
https://doaj.org/article/3d44f0e51fd843db87f90dda4d717ec5
Autor:
Xingwang Zhou, Yuanguo Ling, Junshuan Cui, Xiang Wang, Niya Long, Wei Teng, Jian Liu, Xin Xiang, Hua Yang, Liangzhao Chu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Mitochondrial RNA modification (MRM) plays a crucial role in regulating the expression of key mitochondrial genes and promoting tumor metastasis. Despite its significance, comprehensive studies on MRM in lower grade gliomas (LGGs) remain unk
Externí odkaz:
https://doaj.org/article/82ad99fcdfc14648aa47ec7c46e00103
Publikováno v:
Guangdong nongye kexue, Vol 51, Iss 5, Pp 44-55 (2024)
【Objective】Auxin response factors (ARF) are key transcription factors engaged in the auxin signaling system and play significant roles in plant flower and fruit development, organ morphogenesis, hormone control, and stress responses. The study ai
Externí odkaz:
https://doaj.org/article/76ebf563302b43938c7299022d446e5a
Publikováno v:
PeerJ, Vol 12, p e18158 (2024)
Background Cervical cancer (CC) is a neoplasia with a high heterogeneity. We aimed to explore the characteristics of tumor microenvironment (TME) for CC treatment. Methods HPV positive (+) and negative (−) samples from cervical cancer (CC) patients
Externí odkaz:
https://doaj.org/article/b5e29540b2ee49c29e18c91cee112818
Publikováno v:
Frontiers in Microbiomes, Vol 3 (2024)
IntroductionLiquiritigenin (LQ), a natural flavonoid found in traditional Chinese medicine and often administered orally, holds potential to affect both the gut and its microbiota, that potentially mediating or influencing its biological and pharmaco
Externí odkaz:
https://doaj.org/article/81ca17dde9bb4c8493d9936d65512831
Autor:
Nan Li, Jiahao Miao, Yichao Li, Faru Ji, Min Yang, Kunyan Dai, Zixian Zhou, Die Hu, Haiyang Guo, Hong Fang, Hongyang Wang, Maohui Wang, Jing Yang
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37933- (2024)
Rice (Oryza sativa L.) is one of the most extensively farmed food crops, but its development and productivity are significantly impacted by cold stress during the budding period. In this study, transcriptome sequencing was conducted on two types of r
Externí odkaz:
https://doaj.org/article/5c49eb85b2ab4f53aea54d18c4aeec60
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundSenescence-accelerated mouse prone 8 (SAMP8) and age-matched SAMR1 mice are used to study the pathogenesis and therapeutics of Alzheimer’s disease (AD); however, the molecular mechanisms are not completely understood.ObjectiveThis study a
Externí odkaz:
https://doaj.org/article/0f28bf38c3e24ef6a9311d06c955bc64
Autor:
Xuan Lv, Jie Deng, Congying Zhou, Ahsan Abdullah, Ziqian Yang, Zhifang Wang, Lujia Yang, Baoqiang Zhao, Yuchen Li, Zhanhong Ma
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT Stripe rust of wheat is caused by the fungal pathogen Puccinia striiformis f. sp. tritici (Pst). Breeding durably resistant wheat varieties by disrupting the susceptibility (S) gene has an important impact on the control of wheat stripe rust
Externí odkaz:
https://doaj.org/article/fa71544859944f6d8ce847fcc0a2cc61
Autor:
Moemen Eltobgy, Finny Johns, Daniela Farkas, Laura Leuenberger, Sarah P. Cohen, Kevin Ho, Sarah Karow, Gabrielle Swoope, Sonal Pannu, Jeffrey C. Horowitz, Rama K. Mallampalli, Joshua A. Englert, Joseph S. Bednash
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe acute respiratory distress syndrome (ARDS) is a common complication of severe COVID-19 and contributes to patient morbidity and mortality. ARDS is a heterogeneous syndrome caused by various insults, and results in acute hypoxemic resp
Externí odkaz:
https://doaj.org/article/ed9738a1df224151a5403672d4e3582b
Autor:
Xiaoquan Zhang, Juxu Li, Xuexia Xing, Hongchen Li, Songtao Zhang, Jianbo Chang, Fengjie Wei, Yongfeng Zhang, Jinhui Huang, Xuelin Zhang, Zhaojun Wang
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Stigma exsertion is an essential agricultural trait that can promote cross-pollination to improve hybrid seed production efficiency. However, the molecular mechanism controlling stigma exsertion remains unknown. Results In this st
Externí odkaz:
https://doaj.org/article/54f2c2cf3bfc4d538aa628662bd90d85