Zobrazeno 1 - 10
of 174
pro vyhledávání: '"RNA-Seq–RNA sequencing"'
Autor:
Owen Dando, Jamie McQueen, Karen Burr, Peter C. Kind, Siddharthan Chandran, Giles E. Hardingham, Jing Qiu
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Rodent studies have shown that alternative splicing in neurons plays important roles in development and maturity, and is regulatable by signals such as electrical activity. However, rodent-human similarities are less well explored. We compared basal
Externí odkaz:
https://doaj.org/article/ce260b833ff24902a5ce953b3917db8a
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/55fb3997d85d47dbadb2f2fe1bcbb6a2
Autor:
Sajad A. Bhat, Mahmoud Elnaggar, Thomas J. Hall, Gillian P. McHugo, Cian Reid, David E. MacHugh, Kieran G. Meade
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Bovine tuberculosis (bTB), caused by infection with Mycobacterium bovis, continues to cause significant issues for the global agriculture industry as well as for human health. An incomplete understanding of the host immune response contributes to the
Externí odkaz:
https://doaj.org/article/12e73de268d8406192d5e21d3f30bf8f
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The Notch and Wnt signalling pathways play key roles in the formation of inner ear sensory organs, but little is known about their transcriptional effectors and targets in this context. Here, we perturbed Notch and Wnt activities in the embryonic chi
Externí odkaz:
https://doaj.org/article/dd1661b21cdd446e991b5375abe9121a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Epithelial ovarian cancer (EOC) is the most fatal gynaecological malignancy, accounting for over 200,000 deaths worldwide per year. EOC is a highly heterogeneous disease, classified into five major histological subtypes–high-grade serous (HGSOC), c
Externí odkaz:
https://doaj.org/article/3dfd16bfd0dd4c54923619755399d476
Autor:
Dhanasekaran Sivakumaran, Synne Jenum, Aashish Srivastava, Vidar M. Steen, Mario Vaz, Timothy Mark Doherty, Christian Ritz, Harleen M. S. Grewal
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
A large proportion of the global tuberculosis (TB) burden is asymptomatic and not detectable by symptom-based screening, driving the TB epidemic through continued M. tuberculosis transmission. Currently, no validated tools exist to diagnose incipient
Externí odkaz:
https://doaj.org/article/5cacf16ed76c48d981957f22c4c7f4ba
Autor:
Dandan Song, Huan He, Rajitha Indukuri, Zhiqiang Huang, Lina Stepanauskaite, Indranil Sinha, Lars-Arne Haldosén, Chunyan Zhao, Cecilia Williams
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The two estrogen receptors ERα and ERβ are nuclear receptors that bind estrogen (E2) and function as ligand-inducible transcription factors. They are homologues and can form dimers with each other and bind to the same estrogen-response element moti
Externí odkaz:
https://doaj.org/article/738a38fd4263449b9f8981899e871eb4
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The clam Ruditapes philippinarum is an important species in the marine aquaculture industry in China. However, in recent years, the aquaculture of R. philippinarum has been negatively impacted by various bacterial pathogens. In this study, the transc
Externí odkaz:
https://doaj.org/article/c892c0f9c94848aa82dc205c1dc493df
Publikováno v:
Frontiers in Plant Science, Vol 12 (2022)
Black pod rot, caused by Phytophthora palmivora, is a devastating disease of Theobroma cacao L. (cacao) leading to huge losses for farmers and limiting chocolate industry supplies. To understand resistance responses of cacao leaves to P. palmivora, S
Externí odkaz:
https://doaj.org/article/f3b2f0e4eac4404698ceea6741464bb1
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
We and many others have noted the advantages of using heterogeneous (HS) animals to map genes and gene networks associated with both behavioral and non-behavioral phenotypes. Importantly, genetically complex Mus musculus crosses provide substantially
Externí odkaz:
https://doaj.org/article/9fde4c9c622042a8b0eb75bfb8f7ae38