Zobrazeno 1 - 10
of 2 876
pro vyhledávání: '"RNA-SEQ DATA"'
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-5 (2024)
Abstract A recent study reported exaggerated false positives by popular differential expression methods when analyzing large population samples. We reproduce the differential expression analysis simulation results and identify a caveat in the data ge
Externí odkaz:
https://doaj.org/article/e89c8591e60d4256ad344552e73b1633
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background The widely adopted bulk RNA-seq measures the gene expression average of cells, masking cell type heterogeneity, which confounds downstream analyses. Therefore, identifying the cellular composition and cell type-specific gene expre
Externí odkaz:
https://doaj.org/article/62da124aee3640df834c477787b5d64c
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Background Current RNA-seq analysis software for RNA-seq data tends to use similar parameters across different species without considering species-specific differences. However, the suitability and accuracy of these tools may vary when analy
Externí odkaz:
https://doaj.org/article/3a51cfa367b9433ca3a5be7539e3f80a
Chronological transitions of hepatocyte growth factor treatment effects in spinal cord injury tissue
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-11 (2024)
Abstract Inflammatory responses are known to suppress neural regeneration in patients receiving stem cell-based regenerative therapy for spinal cord injury (SCI). Consequently, pathways involved in neurogenesis and immunomodulation, such as the hepat
Externí odkaz:
https://doaj.org/article/45cba96b58ff46dba544d69db81219fb
Autor:
Seungjun Ahn, Somnath Datta
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-7 (2023)
Abstract Background Advances in sequencing technology and cost reduction have enabled an emergence of various statistical methods used in RNA-sequencing data, including the differential co-expression network analysis (or differential network analysis
Externí odkaz:
https://doaj.org/article/c017579d5d8a424e8ca875c33050280f
Autor:
Jon Patrick T. Garcia, Lemmuel L. Tayo
Publikováno v:
Biology, Vol 13, Iss 10, p 787 (2024)
Bipolar disorder (BPD) is a serious psychiatric condition that is characterized by the frequent shifting of mood patterns, ranging from manic to depressive episodes. Although there are already treatment strategies that aim at regulating the manifesta
Externí odkaz:
https://doaj.org/article/79cba9635a1749bdb67efb2e86939c77
Publikováno v:
Translational Medicine Communications, Vol 8, Iss 1, Pp 1-8 (2023)
Abstract Deconvolution of RNA sequencing data is a computational method used to estimate the relative proportions of different cell types or subpopulations within a heterogeneous sample based on gene expression profiles. This technique is particularl
Externí odkaz:
https://doaj.org/article/1af306fd6b6148e9ac90d32a0a40f492
Autor:
Mostafa Rezapour, Stephen J. Walker, David A. Ornelles, Patrick M. McNutt, Anthony Atala, Metin Nafi Gurcan
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionOur study undertakes a detailed exploration of gene expression dynamics within human lung organ tissue equivalents (OTEs) in response to Influenza A virus (IAV), Human metapneumovirus (MPV), and Parainfluenza virus type 3 (PIV3) infection
Externí odkaz:
https://doaj.org/article/3aa893f9eca64910900f5de919545a0d
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27132- (2024)
In Catharanthus roseus, vital plant hormones, namely methyl jasmonate (MeJA) and ethylene, serve as abiotic triggers, playing a crucial role in stimulating the production of specific secondary compounds with anticancer properties. Understanding how p
Externí odkaz:
https://doaj.org/article/31b17dd0484e4bacab27db8478d8772d
Autor:
Sanjeena Subedi
Publikováno v:
Analytics, Vol 2, Iss 2, Pp 426-437 (2023)
Matrix variate longitudinal discrete data can arise in transcriptomics studies when the data are collected for N genes at r conditions over t time points, and thus, each observation Yn for n=1,…,N can be written as an r×t matrix. When dealing with
Externí odkaz:
https://doaj.org/article/80bc3828ce94430fb400720a5d2d962e