Zobrazeno 1 - 10
of 66
pro vyhledávání: '"RNA-Binding Proteins/metabolism"'
Autor:
Magdalena Harakalova, Jolanthe Lingeman, Shahrzad Sepehrkhouy, Aryan Vink, Folkert W. Asselbergs, Dennis Dooijes, Albert J. H. Suurmeijer, Wouter P. te Rijdt, Roel Goldschmeding, Frederique S. A. M. Schuiringa, Johannes Peter van Tintelen, Zoë Joy van der Klooster
Publikováno v:
Journal of Cellular and Molecular Medicine
Journal of cellular and molecular medicine. Wiley
Journal of cellular and molecular medicine, 25(6), 3160-3166. Wiley-Blackwell
Journal of cellular and molecular medicine. Wiley
Journal of cellular and molecular medicine, 25(6), 3160-3166. Wiley-Blackwell
Genetic cardiomyopathy is caused by mutations in various genes. The accumulation of potentially proteotoxic mutant protein aggregates due to insufficient autophagy is a possible mechanism of disease development. The objective of this study was to inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83aee4a3967ee22ba0190854fd34685d
https://doi.org/10.1111/jcmm.16388
https://doi.org/10.1111/jcmm.16388
Autor:
Diana M. Dincã, Louison Lallemant, Anchel González-Barriga, Noémie Cresto, Sandra O. Braz, Géraldine Sicot, Laure-Elise Pillet, Hélène Polvèche, Paul Magneron, Aline Huguet-Lachon, Hélène Benyamine, Cuauhtli N. Azotla-Vilchis, Luis E. Agonizantes-Juárez, Julie Tahraoui-Bories, Cécile Martinat, Oscar Hernández-Hernández, Didier Auboeuf, Nathalie Rouach, Cyril F. Bourgeois, Geneviève Gourdon, Mário Gomes-Pereira
Publikováno v:
Nature Communications
Nature Communications, 2022, 13 (1), pp.3841. ⟨10.1038/s41467-022-31594-9⟩
Nature Communications, 2022, 13 (1), pp.3841. ⟨10.1038/s41467-022-31594-9⟩
Brain dysfunction in myotonic dystrophy type 1 (DM1), the prototype of toxic RNA disorders, has been mainly attributed to neuronal RNA misprocessing, while little attention has been given to non-neuronal brain cells. Here, using a transgenic mouse mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53a9936d2f875fcec726c6a77aaaa26
https://hal.sorbonne-universite.fr/hal-03715682
https://hal.sorbonne-universite.fr/hal-03715682
Publikováno v:
Cornelius, V A, Naderi-Meshkin, H, Kelaini, S & Margariti, A 2022, ' RNA-Binding Proteins: Emerging Therapeutics for Vascular Dysfunction ', Cells, vol. 11, no. 16, 2494 . https://doi.org/10.3390/cells11162494
Vascular diseases account for a significant number of deaths worldwide, with cardiovascular diseases remaining the leading cause of mortality. This ongoing, ever-increasing burden has made the need for an effective treatment strategy a global priorit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d270f80668c4331aaffff1a84a0c12
https://doi.org/10.3390/cells11162494
https://doi.org/10.3390/cells11162494
Autor:
Daan Dierickx, Philippe Gaulard, Carlos Graux, Koen Debackere, Laurence de Leval, Nicole Mentens, Jan Cools, Lucienne Michaux, Kris Jacobs, Thomas Tousseyn, Sofie Demeyer, Olga Gielen, Michaël Broux, Iwona Wlodarska, Marlies Vanden Bempt, Lukas Marcelis, Gregor Verhoef
Publikováno v:
Nature communications, vol. 12, no. 1, pp. 3705
Nature communications, Vol. 12, no.1, p. 3705 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature communications, Vol. 12, no.1, p. 3705 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Peripheral T-cell lymphoma (PTCL) is a heterogeneous group of non-Hodgkin lymphomas with poor prognosis. Up to 30% of PTCL lack distinctive features and are classified as PTCL, not otherwise specified (PTCL-NOS). To further improve our understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133ce4ef8eab96b32fc1be9ac3896731
https://doi.org/10.1038/s41467-021-24037-4
https://doi.org/10.1038/s41467-021-24037-4
Autor:
Paul Lasko, Julian König, Andrea Hildebrandt, Jean-Yves Roignant, Annabelle Dold, Petra Beli, Niankun Liu, Anke Busch, Cornelia Rücklé, Kathi Zarnack, Hong Han, Heike Hänel, Mirko Brüggemann
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 16, Iss 1, p e1008581 (2020)
Plos Genetics, 16
Plos Genetics, 16, 1
PLoS genetics, vol. 16, no. 1, pp. e1008581
PLoS Genetics, Vol 16, Iss 1, p e1008581 (2020)
Plos Genetics, 16
Plos Genetics, 16, 1
PLoS genetics, vol. 16, no. 1, pp. e1008581
Makorins are evolutionary conserved proteins that contain C3H-type zinc finger modules and a RING E3 ubiquitin ligase domain. In Drosophila, maternal Makorin 1 (Mkrn1) has been linked to embryonic patterning but the mechanism remained unsolved. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df129a2c659e01f8f85405e8f223bb5
http://publikationen.ub.uni-frankfurt.de/files/52553/container.zip
http://publikationen.ub.uni-frankfurt.de/files/52553/container.zip
Autor:
Miguel Angel de la Fuente, Paul A. Anderson, Johannes Popow, Alexis A. Jourdain, Maria Simarro, Jean-Claude Martinou
Publikováno v:
UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname
UVaDOC: Repositorio Documental de la Universidad de Valladolid
Universidad de Valladolid
Nucleic acids research, vol. 45, no. 19, pp. 10941-10947
Digital.CSIC. Repositorio Institucional del CSIC
Nucleic Acids Research
instname
UVaDOC: Repositorio Documental de la Universidad de Valladolid
Universidad de Valladolid
Nucleic acids research, vol. 45, no. 19, pp. 10941-10947
Digital.CSIC. Repositorio Institucional del CSIC
Nucleic Acids Research
Producción Científica
The FASTK family proteins have recently emerged as key post-transcriptional regulators of mitochondrial gene expression. FASTK, the founding member and its homologs FASTKD1–5 are architecturally related RNA-binding prot
The FASTK family proteins have recently emerged as key post-transcriptional regulators of mitochondrial gene expression. FASTK, the founding member and its homologs FASTKD1–5 are architecturally related RNA-binding prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bb511b150faf6e4c7dbd040aa3901e
https://doi.org/10.1093/nar/gkx772
https://doi.org/10.1093/nar/gkx772
Autor:
Martijn A. van der Ent, Grietje Molema, David Ginsburg, Kristina L. Hunker, William C. Aird, Audrey C. A. Cleuren, Santhi K. Ganesh, Hui Jiang, Andrew Yee, David R. Siemieniak
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 116(47), 23618-23624. NATL ACAD SCIENCES
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Endothelial cells (ECs) are highly specialized across vascular beds. However, given their interspersed anatomic distribution, comprehensive characterization of the molecular basis for this heterogeneity in vivo has been limited. By applying endotheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3844edf4e9540fe28c17ded36731085
https://doi.org/10.1101/708701
https://doi.org/10.1101/708701
Publikováno v:
Oncotarget, vol. 7, no. 37, pp. 58717-58727
Oncotarget
Oncotarget
// Seung-Hee Jo 1,2 , Dong Eun Kim 3 , Andrea Clocchiatti 1,2 and G. Paolo Dotto 1,3 1 Cutaneous Biology Research Center, Massachusetts General Hospital, Charlestown, MA, USA 2 Department of Dermatology, Harvard Medical School, Boston, MA, USA 3 Depa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea12f5aaed1cf56a0d17a8e7fc46ffdd
https://doi.org/10.18632/oncotarget.11227
https://doi.org/10.18632/oncotarget.11227
Autor:
Ivan Stamenkovic, Mario L. Suvà, Paolo Provero, Michalina Janiszewska, Nils Degrauwe, Tommy Beat Schlumpf, Alexandra Cauderay, Renato Paro, Patricia Martin, Nicolo Riggi
Publikováno v:
Genes and Development
Cell Reports
Cell Reports, Vol 15, Iss 8, Pp 1634-1647 (2016)
Cell reports, vol. 15, no. 8, pp. 1634-1647
Cell Reports, 15 (8)
Cell Reports
Cell Reports, Vol 15, Iss 8, Pp 1634-1647 (2016)
Cell reports, vol. 15, no. 8, pp. 1634-1647
Cell Reports, 15 (8)
Cancer stem cells (CSCs) can drive tumor growth, and their maintenance may rely on post-transcriptional regulation of gene expression, including that mediated by microRNAs (miRNAs). The let-7 miRNA family has been shown to induce differentiation by s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b70f1f268d7b92b94859d969d4856aa8
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, vol. 8, pp. e43400
eLife, Vol 8 (2019)
eLife, vol. 8, pp. e43400
Sleep depriving mice affects clock-gene expression, suggesting that these genes contribute to sleep homeostasis. The mechanisms linking extended wakefulness to clock-gene expression are, however, not well understood. We propose CIRBP to play a role b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::500f41320a647b907ec1298dc94fec97
https://pubmed.ncbi.nlm.nih.gov/30720431
https://pubmed.ncbi.nlm.nih.gov/30720431