Zobrazeno 1 - 10
of 27
pro vyhledávání: '"RNA sequence optimization"'
Autor:
Junfeng Jiang, Tao Zeng, Li Zhang, Xingfei Fan, Qishu Jin, Haitao Ni, Yusheng Ye, Lipeng Cheng, Li Li, Liujun Wang, Sha Xu, Yu Yang, Juan Gu, Bing Guo, Lei Wang, Xin Li, Yingyi Qin, Jiaxi Li, Jinjiang Wang, Xi Chen, Minjuan Wu, Qi-long Ying, Xingjun Qin, Yefei Wang, Yue Wang
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-8 (2022)
Highlights Cas9 RNA functions as a miRNA sponge. Let-7 is the dominant regulated miRNA by Cas9 RNA. RNA sequence optimization of Cas9 by synonymous mutation improves its safety.
Externí odkaz:
https://doaj.org/article/8fe7ac32766e436bb70ab060b5e9d6e8
Autor:
Jiang, Junfeng1,2 (AUTHOR), Zeng, Tao1,2,3 (AUTHOR), Zhang, Li4 (AUTHOR), Fan, Xingfei1,2 (AUTHOR), Jin, Qishu5 (AUTHOR), Ni, Haitao1 (AUTHOR), Ye, Yusheng1 (AUTHOR), Cheng, Lipeng1 (AUTHOR), Li, Li1 (AUTHOR), Wang, Liujun1 (AUTHOR), Xu, Sha1 (AUTHOR), Yang, Yu1 (AUTHOR), Gu, Juan1 (AUTHOR), Guo, Bing6,7,8 (AUTHOR), Wang, Lei6,7,8 (AUTHOR), Li, Xin6,7,8 (AUTHOR), Qin, Yingyi9 (AUTHOR), Li, Jiaxi10 (AUTHOR), Wang, Jinjiang10 (AUTHOR), Chen, Xi11 (AUTHOR)
Publikováno v:
Molecular Cancer. 6/24/2022, Vol. 21 Issue 1, p1-8. 8p.
Autor:
Tani, Hidenori1 (AUTHOR) hidenori.tani@yok.hamayaku.ac.jp
Publikováno v:
International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 22, p12284. 32p.
Autor:
Chehelgerdi, Mohammad1,2 (AUTHOR) Chehelgerdi1992@gmail.com, Chehelgerdi, Matin1,2 (AUTHOR)
Publikováno v:
Molecular Cancer. 7/7/2023, Vol. 22 Issue 1, p1-104. 104p.
Autor:
Zhao, Yan1,2 (AUTHOR), Li, Xiaomeng2 (AUTHOR), Xiang, Mei-Hao2 (AUTHOR), Gao, Feng1 (AUTHOR), Qu, Fengli1,2 (AUTHOR) fengliquhn@hotmail.com, Li, Mingfang1 (AUTHOR), Lu, Limin1 (AUTHOR) lulimin816@hotmail.com
Publikováno v:
Microchimica Acta. Jul2022, Vol. 189 Issue 7, p1-9. 9p.
Optimization of real-world black-box functions defined over purely categorical variables is an active area of research. In particular, optimization and design of biological sequences with specific functional or structural properties have a profound i
Externí odkaz:
http://arxiv.org/abs/2202.03712
Publikováno v:
Journal of Pharmaceutical Investigation (2093-5552); Nov2023, Vol. 53 Issue 6, p803-826, 24p
Autor:
Van Hoecke, Lien1,2 (AUTHOR), Verbeke, Rein3,4 (AUTHOR), Dewitte, Heleen3,4 (AUTHOR), Lentacker, Ine3,4 (AUTHOR), Vermaelen, Karim4,5 (AUTHOR), Breckpot, Karine6 (AUTHOR) karine.breckpot@vub.be, Van Lint, Sandra4,5 (AUTHOR) Sandra.vanlint@ugent.be
Publikováno v:
Molecular Cancer. 3/3/2021, Vol. 20 Issue 1, p1-14. 14p.
Autor:
Kouno, Takahide, Shibata, Satoshi, Shigematsu, Megumi, Hyun, Jaekyung, Kim, Tae Gyun, Matsuo, Hiroshi, Wolf, Matthias
Publikováno v:
Nature Communications; 7/7/2023, Vol. 14 Issue 1, p1-14, 14p
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Autor:
Leppek, Kathrin, Byeon, Gun Woo, Kladwang, Wipapat, Wayment-Steele, Hannah K., Kerr, Craig H., Xu, Adele F., Kim, Do Soon, Topkar, Ved V., Choe, Christian, Rothschild, Daphna, Tiu, Gerald C., Wellington-Oguri, Roger, Fujii, Kotaro, Sharma, Eesha, Watkins, Andrew M., Nicol, John J., Romano, Jonathan, Tunguz, Bojan, Diaz, Fernando, Cai, Hui
Publikováno v:
Nature Communications; 10/23/2022, Vol. 13 Issue 1, p1-22, 22p