Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex

Autor: Zhang, Wen, Tam, Chun Pong, Walton, Travis, Fahrenbach, Albert C., Birrane, Gabriel, Szostak, Jack W.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2017 Jul . 114(29), 7659-7664.

Externí odkaz: https://www.jstor.org/stable/26486677

RNA catalysis, thermodynamics and the origin of life

Autor: Abraham Szöke, Sara M. O'Rourke, Josh Blaustein, Michael P. Robertson, William G. Scott

Publikováno v: Scott, WG; Szöke, A; Blaustein, J; O'Rourke, SM; & Robertson, MP. (2014). RNA catalysis, thermodynamics and the origin of life. Life, 4(2), 131-141. doi: 10.3390/life4020131. UC Santa Cruz: Retrieved from: http://www.escholarship.org/uc/item/3dg5r4bv
Life (Basel, Switzerland), vol 4, iss 2
Life : Open Access Journal
Life, Vol 4, Iss 2, Pp 131-141 (2014)

The RNA World Hypothesis posits that the first self-replicating molecules were RNAs. RNA self-replicases are, in general, assumed to have employed nucleotide 5'-polyphosphates (or their analogues) as substrates for RNA polymerization. The mechanism b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebca9b5840ea958cac746618a1b4e6c5
http://www.escholarship.org/uc/item/3dg5r4bv

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