Zobrazeno 1 - 10
of 34
pro vyhledávání: '"RNA regulatory pathways"'
Publikováno v:
Brain Circulation, Vol 9, Iss 4, Pp 228-239 (2023)
BACKGROUND: Ischemic stroke (IS) is a life-threatening condition with limited treatment options; thus, finding the potential key genes for novel therapeutic targets is urgently needed. This study aimed to explore novel candidate genes and pathways of
Externí odkaz:
https://doaj.org/article/87cc690dabd64a5e9363fd61b2f0edd3
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: Accumulating evidence suggests that postmenopausal osteoporosis (PMOP) is a common chronic systemic metabolic bone disease, but its specific molecular pathogenesis remains unclear. This study aimed to identify novel genetic diagnostic mar
Externí odkaz:
https://doaj.org/article/5a68909562244ba1b56b02c9c24a3225
Publikováno v:
PeerJ, Vol 11, p e15437 (2023)
Background Diabetic nephropathy (DN), the most intractable complication in diabetes patients, can lead to proteinuria and progressive reduction of glomerular filtration rate (GFR), which seriously affects the quality of life of patients and is associ
Externí odkaz:
https://doaj.org/article/942dbd232cfb4eeba76183d5ea7661cf
Autor:
Jingru Li, Chaozhong Li, Yulan Zhao, Xinyu Wu, Shuai Yu, Guihu Sun, Peng Ding, Si Lu, Lijiao Zhang, Ping Yang, Yunzhu Peng, Jingyun Fu, Luqiao Wang
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
In order to seek a more outstanding diagnosis and treatment of diabetic retinopathy (DR), we predicted the miRNA biomarkers of DR and explored the pathological mechanism of DR through bioinformatics analysis.Method: Based on public omics data and dat
Externí odkaz:
https://doaj.org/article/1ba90f799ac94363b684df318d920e88
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: The clinical value of the biomarkers of bladder cancer (BC) is limited due to their low sensitivity or specificity. As a biomarker, DLG associated protein 5 (DLGAP5) is a potential cell cycle regulator in cancer cell carcinogenesis. Howev
Externí odkaz:
https://doaj.org/article/2128dd7368a04ee9bcc76012d6d22be8
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Rheumatoid arthritis (RA) is the most common chronic autoimmune connective tissue disease. However, early RA is difficult to diagnose due to the lack of effective biomarkers. This study aimed to identify new biomarkers and mechani
Externí odkaz:
https://doaj.org/article/e891ca20007642108edf097e435d30a2
Publikováno v:
Frontiers in Neurology, Vol 12 (2022)
BackgroundFriedreich's ataxia (FRDA) is a familial hereditary disorder that lacks available therapy. Therefore, the identification of novel biomarkers and key mechanisms related to FRDA progression is urgently required.MethodsWe identified the up-reg
Externí odkaz:
https://doaj.org/article/eedb8d5762cd41c8a879340933432f6c
Akademický článek
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Autor:
Guoqing Li, Jun Zhang, Dechen Liu, Qiong Wei, Hui Wang, Yingqi Lv, Zheng Ye, Gaifang Liu, Ling Li
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Diabetic nephropathy (DN) is one of the most common microvascular complications in diabetic patients, and is the main cause of end-stage renal disease. The exact molecular mechanism of DN is not fully understood. The aim of this study was to identify
Externí odkaz:
https://doaj.org/article/50373e48570f48db960ce65196c4f156
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-15 (2021)
Journal of Translational Medicine
Journal of Translational Medicine
Background Rheumatoid arthritis (RA) is the most common chronic autoimmune connective tissue disease. However, early RA is difficult to diagnose due to the lack of effective biomarkers. This study aimed to identify new biomarkers and mechanisms for R